Publications

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polymerase chain reaction evidence of ehrlichia chaffeensis, an etiologic agent of human ehrlichiosis, in dogs from southeast virginia.to ascertain whether dogs are naturally infected with ehrlichia chaffeensis.19968836370
granulocytic ehrlichiosis in dogs from north carolina and virginia.medical records of 3 dogs from north carolina and 3 dogs from virginia with ehrlichial morulae in circulating neutrophils were studied retrospectively. two clinically distinct disease syndromes, including chronic, moderate to severe anemia (n = 3) and polyarthritis (n = 2) were associated with canine granulocytic ehrlichiosis (cge) in these dogs. one dog was clinically healthy, and abnormalities were not detected during physical examination. clinical signs were nonspecific and included fever, le ...19989560760
sequential evaluation of dogs naturally infected with ehrlichia canis, ehrlichia chaffeensis, ehrlichia equi, ehrlichia ewingii, or bartonella vinsonii.historically, disease manifestations in dogs seroreactive to ehrlichia canis antigens by indirect immunofluorescent antibody testing have been attributed to infection with either e. canis or ehrlichia ewingii. a 1996 study by dawson and colleagues provided pcr evidence that healthy dogs from southeastern virginia could be naturally infected with ehrlichia chaffeensis. this observation stimulated us to determine which ehrlichia spp. infected sick dogs that were referred to our hospital from the s ...19989705408
characterization of the major antigenic protein 2 of ehrlichia canis and ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis.canine monocytic ehrlichiosis, caused by ehrlichia canis or ehrlichia chaffeensis, can result in clinical disease in naturally infected animals. coinfections with these agents may be common in certain areas of endemicity. currently, a species-specific method for serological diagnosis of monocytic ehrlichiosis is not available. previously, we developed two indirect enzyme-linked immunosorbent assays (elisas) using the major antigenic protein 2 (map2) of e. chaffeensis and e. canis. in this study, ...200312853379
natural and experimental infection of white-tailed deer (odocoileus virginianus) from the united states with an ehrlichia sp. closely related to ehrlichia ruminantium.an ehrlichia sp. (panola mountain [pm] ehrlichia sp.) closely related to ehrlichia ruminantium was recently detected in a domestic goat experimentally infested with lone star ticks (lsts, amblyomma americanum) collected from georgia, usa. the infected goat exhibited pyrexia and mild clinical pathologic abnormalities consistent with ehrlichiosis. at least two other ehrlichia species (ehrlichia chaffeensis and ehrlichia ewingii) are maintained in nature by a cycle involving lsts as the primary vec ...200818436670
prevalence of ehrlichia chaffeensis and ehrlichia ewingii in amblyomma americanum and dermacentor variabilis collected from southeastern virginia, 2010-2011.amblyomma americanum is the most commonly encountered tick species in southeastern virginia, representing approximately 95% of the human-biting tick population in this area. here we investigated the prevalence of ehrlichia chaffeensis and ehrlichia ewingii in questing amblyomma americanum and dermacentor variabilis ticks collected from multiple sites in southeastern virginia from 2010 to 2011. although both ehrlichia species were detected in amblyomma americanum, no evidence of either pathogen w ...201425155340
a naval academy midshipman with ehrlichiosis after summer field exercises in quantico, virginia.a case of human ehrlichiosis (caused by infection with ehrlichia chaffeensis) is presented. the patient was a female naval academy midshipman with a 26-day history of daily field training with the u.s. marines near quantico, virginia. she presented with a several-day history of myalgias, fever, and frontal headache. during her clinical course, she developed fever to 104 degrees f, dry cough, dyspnea on exertion, arthralgias, and nephrotic syndrome. she did not develop a rash. laboratory studies ...200111272720
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