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rugulotrosins a and b: two new antibacterial metabolites from an australian isolate of a penicillium sp.two new antibacterial agents, rugulotrosin a (1) and b (2), were obtained from cultures of a penicillium sp. isolated from soil samples acquired near sussex inlet, new south wales, australia. rugulotrosin a (1) is a chiral symmetric dimer, and its relative stereostructure was determined by spectroscopic and x-ray crystallographic analysis. rugulotrosin b (2) is a chiral asymmetric dimer isomeric with 1. its structure was determined by spectroscopic analysis with comparison to the co-metabolite 1 ...200415104517
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