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autosomal inheritance of deltamethrin resistance in field populations of triatoma infestans (heteroptera: reduviidae) from argentina.triatoma infestans (klug) is the major chagas disease vector in the southern cone area of south america, and its chemical control is based on the use of pyrethroid insecticides. resistance to deltamethrin in salta province, argentina, has been detected in field populations since 2002, causing the failure of vector control campaigns in this disease-endemic area. the inheritance of deltamethrin resistance in t. infestans was evaluated through reciprocal crosses conducted between resistant and susc ...201020205232
etiological treatment of young women infected with trypanosoma cruzi, and prevention of congenital transmission.the objective was to detect trypanosoma cruzi infection in 32 children in salta, argentina, born to 16 chronically infected young women who were treated with benznidazole. tests were performed to assess the efficacy of treatment after 14 years. at the end of the follow up, 87.5% of the women were non-reactive to eia tests, 62.5% to iha and 43.8% to ifa. 62.5% of the women were non-reactive according to two or three serological tests. no infected children were detected among the newborns of mothe ...200919967227
congenital chagas disease involves trypanosoma cruzi sub-lineage iid in the northwestern province of salta, argentina.trypanosoma cruzi is genetically classified into six discrete phylogenetic lineages on the basis of different genetic markers. identifying lineages circulating among humans in different areas is essential to understand the molecular epidemiology of chagas disease. in the present study, 18 t. cruzi isolates from congenitally infected newborns in the northwestern province of salta-argentina were studied by multilocus enzyme electrophoresis (mlee) and random amplified polymorphic dna (rapd). all is ...200919162237
high prevalence of congenital trypanosoma cruzi infection and family clustering in salta, argentina.trypanosoma cruzi, the causative agent of chagas' disease, is transmitted mainly by insect vectors, but congenital and transfusion-borne infections occasionally occur. the factors that are involved in transmission from mother to offspring are not well understood. the objective of this study was to study the presence of t cruzi infection in children who were born to infected mothers and in the children's siblings to evaluate the epidemiologic risk factors associated with congenital transmission o ...200515930194
clinical status and parasitic infection in a wichí aboriginal community in salta, argentina.in a study, carried out in 2000, of the clinical and parasitological status of a wichi aboriginal community living in the suburbs of tartagal, northern salta, argentina, 154 individuals were screened for parasitic infections. ninety-five faecal samples were also obtained from the same population. ninety-three percent of the subjects were positive for 1 or more of the parasites investigated by direct test and 70.5% of them had parasitic superinfection. the most frequent helminths were strongyloid ...200315307425
canine infection and the possible role of dogs in the transmission of american tegumentary leishmaniosis in salta, argentina.some leishmania species affect humans in two principal forms: visceral and cutaneous leishmaniosis (cl). several studies have identified dogs as the main reservoirs of the visceral leishmaniosis (vl) caused by leishmania infantum. the purpose of this work was to carry out a survey of the canine population associated with human cases of american tegumentary leishmaniosis (atl), in order to establish the clinical, parasitological, serological and immunological characteristics of the canine disease ...200212446084
[mucocutaneous leishmaniasis in naturally infected dogs in salta, argentina].the objective of the present study is to describe two cases of dogs with mucocutaneous lesions caused by leishmania spp. both dogs presented destruction of the nasal septum, hyperemia with soft palate edema and barking alteration due to laryngeal compromise. biopsies were taken from the lesion border and leishmania spp. amastigotes were seen in the imprints. the dogs presented positive serology when complex soluble antigen from leishmania mexicana was used. one of the dogs was also suspected to ...200011008704
[the transmission de chagas disease in salta and the detection of congenital cases].data on the prevalence of trypanosoma cruzi infection is presented for the province of salta, argentina. special emphasis is given to the detection of congenital transmission and to the economic benefits of preventing chagas' disease. seroepidemiological data obtained from 20 year old army draftees revealed a reduction, from 22.7 to 11.11% between 1964 and 1985. in university students, a rate of 0.96% was found in 1998. surveys carried out during 1996 showed that more than 15% of the pregnant wo ...199910668257
endemic trypanosoma cruzi infection in indian populations of the gran chaco territory of south america: performance of diagnostic assays and epidemiological features.the relative specificities and sensitivities of several serological assays for the diagnosis of trypanosoma cruzi infection were estimated in indian populations of argentina and paraguay. the results obtained with the assays, which proved to be most reliable, were used to study the distribution of the parasite in these populations. serological evidence of t. cruzi infection was demonstrated in 256 (37.7%) of 679 indians living in relatively small and isolated communities in the salta province of ...199910492670
[study of cases of leishmaniasis in the province of salta: evidences of mixed infection with trypanosoma cruzi and leishmania spp].in many regions of south america there are overlapping endemic areas for american trypanosomiasis (chagas' disease) and leishmaniasis. t. cruzi and leishmania spp, the causative agents of these parasitoses belong to the trypanosomatidae family and share various antigens that cause cross-reactivity in serological diagnosis when complex antigenic mixtures are used. we studied patients who sought medical attention because of cutaneous or mucocutaneous lesions typical of leishmaniasis infection. the ...19969035482
[congenital chagas disease in the city of salta, argentina].the immune response to trypanosoma cruzi was studied in our hospital in 937 pregnant women(pw) and their 929 newborns(nb), group i; 4 nb from this center not included in the first group, group ii and 35 nb derived from other centers, group iii. two positive results among indirect hemagglutination (iha), complement fixation(cf) and indirect hemagglutination(iha), complement fixation(cf) and indirect immunofluorescence(iif) tests were considered as the criterion of previous infection with t. cruzi ...19938278744
a cost-benefit analysis of chagas disease control in north-western argentina.chagas disease has been controlled in the department of anta, province of salta, argentina, through a series of vector control interventions beginning in 1983. based on data from this programme, together with estimates of the value of benefits accruing to the programme due to avoidance of new cases of chagas disease, we present an analysis of costs and benefits of the vector control interventions. under all assumptions, the interventions have been highly profitable from a societal point of view, ...20069764315
[congenital chagas' disease in the province of salta, argentina, from 1980 to 1997].this is the experience of 18 years of attending newborn infants suffering from congenital chagas' disease. from a variety of sources in the provincial health system, the mother-child hospital in the city of salta, country hospitals and out-patient care, 102 newborn and infants were detected and diagnosed. the newborn were classified into two main groups, one being sub-classified according to diagnostic opportunity. the diagnostic methodology, clinical presentation, treatment and follow-up of the ...200610881107
[congenital chagas-mazza disease in salta, argentina].a study was carried out on t. cruzi infection in pregnant women in the guemes area in salta province; the rate of infection was 12.3%. of newborn children studied by the microhematocrit technique, 8.8% were diagnosed with chagas' disease. all of them were treated with benznidazol (5mg/kg/day) for one month; all of them presented anemia, which was interpreted to be an adverse drug reaction. the microhematocrit technique is believed to represent the best option for diagnosis of this disease in new ...200610881099
[consideration of chagas' disease in salta]. 201114197543
inheritance of resistance to pyrethroids in triatoma infestans, the main chagas disease vector in south america.an outbreak of pyrethroid resistance was recently detected in triatoma infestans from northern argentina. to analyze the inheritance of the resistant phenotype, we carried out experimental crosses between resistant (r) and susceptible (s) strains captured in argentina during 2005. the r strain was collected from sprayed houses in the north of the province of salta while the s strain was collected in the province of chaco. both strains were bred in the laboratory for reciprocal crosses (f1), inte ...201020674788
epidemiology of american tegumentary leishmaniasis and trypanosoma cruzi infection in the northwestern argentina.background. endemic areas of tegumentary leishmaniasis (tl) in salta, argentina, present some overlap zones with the geographical distribution of chagas disease, with mixed infection cases being often detected. objectives. the purpose of this study was to determine the magnitude of leishmania sp. infection and potential associated risk factors, the serologic prevalence of t. cruzi, and the presence of t. cruzi-leishmania sp. mixed infection in a region of the northwest of argentina. methods. cro ...201627777950
microgeographical study of insecticide resistance in triatoma infestans from argentina.chagas disease is a chronic parasitic infection restricted to america where it is currently estimated that 90 million people are at risk of acquiring the infection. chemical control with pyrethroid insecticides has been effective to reduce disease transmission in several areas of the southern cone, although insecticide resistance has evolved and diminished the campaigns' results. considering previous reports on the different levels of resistance between triatoma infestans from different geograph ...201323962389
clinical and epidemiological features of leishmaniasis in northwestern-argentina through a retrospective analysis of recent cases.leishmaniasis is a parasitic disease caused by hemoflagellates of the genus leishmania and is transmitted to humans by the bite of infected phlebotomine sandflies. depending on the leishmania species, the disease has different clinical forms including cutaneous, mucocutaneous, and visceral manifestations. previous studies performed in endemic zones of northwestern-argentina, during epidemic outbreaks, have been important for detecting patients suffering from the acute phase of the disease, but h ...201626611809
[immunoenzymatic evaluation of the recombinant sapa protein of trypanosoma cruzi in naturally infected dogs].we evaluated the recombinant antigen sapa (shed acute phase antigen) for the detection of trypanosoma cruzi antibodies in sera from naturally infected dogs. the technique used was elisa and the antigens were a homogenate of parasite t. cruzi (elisa-h) and the recombinant sapa (elisa-sapa). we analyzed 93 sera from dogs by elisa-h and elisa-sapa, which were grouped as follows: g1: 11 negative control sera from the city of salta, g2: 11 positive control sera from dogs naturally infected with t. cr ...201223102466
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