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longitudinal studies of the immune response of colombian patients infected with trypanosoma cruzi and t. rangeli.two groups of patients were examined for anti-trypanosoma cruzi antibodies by immunofluorescence and elisa (i) inhabitants of the village and surrounding rural area of tibu, norte de santander, columbia (n = 327) and (ii) employees of the empresa colombiana de petroleos (ecopetrol, n = 849). the latter group had a lower rate of positive serology (12 as compared to 29%) but the distributions of antibody titres were very similar in the two groups. a total of 119 serum samples (37 village and 82 ec ...19883136418
comparison of four serological tests for the diagnosis of chagas disease in a colombian endemic area.the performance of 4 serological tests for the diagnosis of chagas disease was evaluated in santander, colombia, a region still presenting active transmission. serum samples from 638 individuals were submitted to an enzyme immunoassay test (eia), using total lysate of a local trypanosoma cruzi strain and 52.5% were positive (335/638). a subset of this group (94 positive individuals and 90 seronegatives) was randomly selected for further serological confirmation. three additional tests were used- ...200415521632
[first report of triatoma nigromaculata (stål, 1859) (hemiptera, reduviidae, triatominae) for colombia].the presence of triatoma nigromaculata was recorded for the first time in colombia in the rural village la playa in the province of cauca. a single female was captured from an outdoor area near a household. the presence of trypanosoma parasites in the specimen was not established due to the poor condition of the specimen. the epidemiological importance of this finding is discussed with respect to the potential for transmission of chagas disease in the province of cauca and, more broadly, in colo ...200516276689
[acute chagas disease in colombia: a rarely suspected disease. report of 10 cases presented during the 2002-2005 period].in colombia, reported cases of acute chagas disease are sporadic.200718154241
its-rflp- and rapd-based genetic variability of trypanosoma cruzi i, human and vector strains in santander, colombia.chagas disease is a severe public health problem in latin-american countries. in colombia, the predominance of trypanosoma cruzi i has been described in the literature, with a broad heterogeneity between strains. however, most of the studies carried out centered on isoenzyme analysis, with a smaller number that focus on other molecular methods. in this report, we discuss the results of a molecular analysis of t. cruzi i strains, isolated from the domestic cycle, from the department of santander, ...200919347363
feeding behaviour of belminus ferroae (hemiptera: reduviidae), a predaceous triatominae colonizing rural houses in norte de santander, colombia.belminus ferroae (hemiptera: reduviidae) was collected from houses in the localities of san alberto and santa catalina in the municipality of toledo, department of norte de santander, colombia. precipitin tests revealed that the main hosts of b. ferroae are insects belonging to the order blattodea, whose haemolymph serves as food (89.43%). a low rate of haematophagy was indicated on rodents, dogs and humans (7.32%) and no natural infection with trypanosoma cruzi was found by either microscopic e ...201020408957
in vitro susceptibility of trypanosoma cruzi strains from santander, colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole.the current chemotherapy for chagas disease is unsatisfactory with only two drugs available for treatment. research to discover new drugs for chagas disease is urgent. hexadecyl-phosphocholine (hpc, miltefosine) has been demonstrated to have in vitro activity against trypanosoma cruzi parasites, but its activity on different colombian t. cruzi strains is not known.200920436996
colombian trypanosoma cruzi major genotypes circulating in patients: minicircle homologies by cross-hybridization analysis.here we present compelling evidence of trypanosoma cruzi genotypes infecting 77 human cases of chagas disease in santander department of colombia. the patients were clinically studied and classified according to the presence of cardiac symptoms. we describe the distribution of the major t. cruzi genotypes circulating in this area by means of direct pcr analysis of blood samples. pcr was directed to minicircles and amplified dnas were hybridized using genotype-specific dna probes. these samples w ...201020709067
[Triatoma dimidiata populations' (Hemiptera: Reduviidae: Triatominae) feeding behaviour in an endemic zone and related epidemiological implications].Determining Triatoma dimidiata's feeding behaviour in domiciliary and extra-domiciliary habitats in an endemic area of the Santander department in Colombia.201122030799
[infection by trypanosoma cruzi in man versus chagas' disease in tibu, north of santander, colombia]. 19714253500
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