Publications

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efficacy and cost of a hepatocellular carcinoma screening program at an australian teaching hospital.western countries are seeing an increasing prevalence of chronic viral hepatitis and a subsequent rise in the incidence of hepatocellular carcinoma (hcc). screening patients at high risk of hcc has become standard practice. the aim of this study was to assess the efficacy and cost of screening high-risk individuals for hcc in an australian tertiary hospital.201020546449
mutation pattern of lamivudine resistance in relation to hepatitis b genotypes: hepatitis b genotypes differ in their lamivudine resistance associated mutation pattern.little is known about differences between individual hepatitis b genotypes and mutation patterns associated with lamivudine resistance. this study analyses the lamivudine-associated mutation pattern in relation to the four major hbv genotypes a-d. the pubmed database was screened for keywords "hbv or hepatitis b," "ymdd," "genotype," and "lamivudine"; all identified publications published till june 2009 were analyzed for differences in mutation pattern. to confirm the literature-based findings t ...201020872711
markers of hepatitis b virus infection and immunity in victoria, australia, 1995 to 2005.estimating the prevalence of chronic hepatitis b virus (hbv) infection in generally low-prevalence populations containing communities with a higher disease burden is difficult. this study was conducted to estimate the prevalence of serological markers of infection with, and immunity to, hbv in the victorian population and to analyse trends in these estimates over time.201020920109
b alert: hepatitis b virus infection in children in victoria.the aim of this study is to determine the demographic, clinical and serological patterns of hepatitis b in children in victoria over a 17-year period.201323480052
increasing hepatitis b viral load is associated with risk of significant liver fibrosis in hbeag-negative but not hbeag-positive chronic hepatitis b.to evaluate the association between demographical features, serum alt and hbv dna and the prevalence of significant fibrosis and inflammation on liver biopsy in patients with chronic hepatitis b.201020492511
markers and risk factors for hcv, hbv and hiv in a network of injecting drug users in melbourne, australia.current injecting drug users (idu) in major street drug markets within greater melbourne were recruited to a longitudinal study on blood borne viruses. here we investigated risk factors for hepatitis c virus (hcv), hepatitis b virus (hbv) and hiv infection in these idu at the time of their recruitment.200919328555
isolated core antibody hepatitis b in sub-saharan african immigrants.chronic hepatitis b virus (hbv) infection is a major health problem in sub-saharan africa, where prevalence is > or =8%, and is increasingly seen in african immigrants to developed countries. a retrospective audit of the medical records of 383 immigrants from sub-saharan africa attending the infectious diseases clinics at the royal melbourne hospital was performed from 2003 to 2006. the hbv, human immunodeficiency virus (hiv) and hepatitis c virus (hcv) serological results are reported, with a f ...200818649341
hepatitis b immunity in a population of drug and alcohol users.the objective of this study was to determine the level of immunity from hepatitis b infection in an australian population of drug and alcohol users, and the validity of self-reported immune status. a cross-sectional survey was employed of drug and alcohol users presenting for treatment, who were clients of de paul house, a community-based drug and alcohol withdrawal service in victoria. outcome measures were: hepatitis b serology and personal reports of hepatitis b immunity. a total of 118 peopl ...200717564878
the prevalence and risk behaviours associated with the transmission of blood-borne viruses among ethnic-vietnamese injecting drug users.to measure the prevalence and determinants of blood-borne virus (bbv) transmission in ethnic vietnamese injecting drug users (idus).200617209266
knowledge about hepatitis and previous exposure to hepatitis viruses in immigrants and refugees from the mekong region.infection with hepatitis b (hbv) and hepatitis c (hcv) viruses is relatively common throughout south-east asia and chronic infection can lead to severe consequences. this study assesses knowledge about hbv and hcv and estimates the seroprevalence of markers for these viruses in immigrants from laos and cambodia.200515782875
pumping iron, risking infection? exposure to hepatitis c, hepatitis b and hiv among anabolic-androgenic steroid injectors in victoria, australia.to measure exposure to the hepatitis c and b viruses and hiv among victorian steroid injectors and evaluate associations between exposure and risk behaviour, and report other characteristics of the study group.200211841901
exposure to hepatitis b and c of tattooists in victoria in 1984.although tattooing is recognized as a risk factor for transmission of hepatitis c, the efficiency with which transmission occurs is unknown. sera stored from a serosurvey of tattooists undertaken in 1984 to test for human immunodeficiency virus (hiv) provided the opportunity to determine the prevalence of serological markers of hepatitis b virus (hbv) and hepatitis c virus (hcv) in tattooists at that time. the stored sera had been obtained from five unregistered and 36 of 37 (97%) of the registe ...19979097270
incidence of bloodborne virus infection and risk behaviours in a cohort of injecting drug users in victoria, 1990-1995.to assess changes in risk behaviours for transmission of bloodborne viruses and incidences and prevalences of these viruses in a field-recruited cohort of injecting drug users.19979236754
risk factors associated with hepatocellular carcinoma notified to the anti-cancer council of victoria in 1991-1992.the study aimed to estimate the prevalence of risk factors for liver disease, particularly hepatitis b virus (hbv) and hepatitis c virus (hcv) infection, in a population-based series of hepatocellular carcinoma, and to assess the feasibility of retrospective surveys in determining risk factors for hepatocellular carcinoma. a survey of all cases of hepatocellular carcinoma diagnosed in 1991 and 1992 documented the high contribution of alcoholic cirrhosis, particularly in australian-born men. low ...19979470270
prevalence of hepatitis c antibodies in patients with clotting disorders in victoria. relationship with other blood borne viruses and liver disease.to elucidate the seroepidemiology of hepatitis c in patients with clotting disorders in comparison with other blood borne infections; to examine the effects of hepatitis c on liver function; and to assess the effectiveness of current screening and inactivation procedures used in preventing the transmission of blood borne viruses by clotting factor preparations.19921321326
australia antigen in acute hepatitis in melbourne. 19715545974
hepatitis c infection in children: a melbourne perspective.to examine the clinical spectrum of hepatitis c virus (hcv) infected children in our care by determining presentation, mode of acquisition, degree of co-infection, biochemical evidence of persisting hepatitis and treatment outcome.200010940177
prevention of vertical transmission of hepatitis b. the place of routine screening in antenatal care, and the case for immunization of infants at risk.many chronic carriers of hepatitis b virus acquire the infection from their mothers at birth; the risk is greatest if the mother either has acute hepatitis b or is a hepatitis be antigen (hbeag)-positive hbsag carrier, but there is some risk also to the infants of mothers who do not carry hbeag. at the royal women's hospital, melbourne, nearly 2% of women attending antenatal clinics are found to be carriers and, without immunization, approximately five infants per 1000 infants delivered (up to 1 ...19846482756
prevalence of antibody to hepatitis b virus in melbourne. 1978739922
early evolving epidemiology of australia antigen hepatitis in melbourne. 19725027547
an assessment of the prevalence of hepatitis b among health care personnel in victoria.the prevalence of past infection with hepatitis b virus in health care personnel was investigated by questionnaire and by a serological survey of personnel in a representative selection of victorian hospitals and institutions. according to the available data, hepatitis b does not appear to have been a major infection problem among health care personnel in victoria. the only occupational group that clearly is at an increased risk of acquiring the infection is the dental profession. nursing staff ...19854069046
antenatal screening practice for infectious diseases by general practitioners in australia.this study aimed to assess self-reported screening practice in the antenatal setting, factors associated with screening, barriers to universal testing for hiv and follow-up for infants born to hepatitis c virus (hcv)-infected women.200919281578
blood-borne virus infections among australian injecting drug users: implications for spread of hiv.to describe the epidemiology of infection with hepatitis c virus (hcv), hepatitis b virus (hbv) and human immunodeficiency virus (hiv) among injecting drug users (idus) in australia, in relation to the potential for further spread of hiv in idus, a cross-sectional analysis was performed on data from a sample of injecting drug users, correlating markers of exposure to blood-borne viruses with sex, age, sexual orientation, primary current drug injected and duration of injecting in rural and metrop ...19947672048
the risk of transmitting hcv, hbv or hiv by blood transfusion in victoria.to report the incidence rate of hepatitis b virus (hbv), hepatitis c virus (hcv) and hiv in victorian repeat blood donors and to derive the residual risk of transmission of the viruses by screened blood transfusion.19979201178
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