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a genome-wide association study with dna pooling identifies the variant rs11866328 in the grin2a gene that affects disease progression of chronic hbv infection.host genetics play a vital role in determining clinical outcomes of hepatitis b virus (hbv) infection. to identify novel susceptibility loci to hbv progression, we carried out a genome-wide association study with dna pooling. this study assessed the relationship between 8 highly-ranked snps selected from our dna pool and disease progression of hbv infection in two independent case-control studies. the first population included 628 asymptomatic hbv carriers (asc) and 1729 progressed hbv carriers ...201122004137
[the analysis of "a" dominant mutation of hepatitis b virus in community-based population of shandong province, china].to determine the rate and type of "a" dominant mutation of hepatitis b virus (hbv) in community-based population of shandong province and the possible effect of hepatitis b vaccination upon "a" dominant mutation.201021604565
[estimation on disease burden related to hepatitis b virus infection in shandong province of china].to comprehensively measure the burden of hepatitis b, liver cirrhosis and liver cancer in shandong province, using disability-adjusted life years (dalys) to estimate the disease burden attribute to hepatitis b virus (hbv) infection.200919957589
a significant reduction in hepatitis b virus infection among the children of shandong province, china: the effect of 15 years of universal infant hepatitis b vaccination.to evaluate the effect of the universal infant hepatitis b vaccination program on hepatitis b infection in china.201019939719
[distribution of hepatitis b virus genotypes in patients with chronic hepatitis b virus infection among 12 cities in china].to investigate the distribution of hepatitis b virus (hbv) genotypes in patients with chronic hbv infection among 11 cities of china.200717850692
[distribution and clinical significance of hepatitis b virus genotypes and subgenotypes in hbeag positive shandong patients with chronic hepatitis b]. 200717362648
[epidemiological feature of hepatitis b in zaozhuang city, shandong province].to study the prevalence and the epidemiological feature of hepatitis b in the population of zaozhuang and the seroepidemiology of hepatitis b virus infection.200212665937
urban-rural comparison of hbv and hcv infection prevalence in eastern china.the present study was initiated to make an urban-rural comparison of the prevalence of cases positive to hepatitis b and c virus (hbv and hcv, respectively) infection markers in densely populated eastern half of china. for this purpose, 10 survey siles were selected, i.e., six sites in urban areas (the city group; beijing, shanghai and four provincial capitals) and four sites in rural areas (the village group; one village each in jilin and shandong provinces, and two villages in shaanxi province ...200011351857
hepatitis b and c virus infection among adult women in jilin province, china: an urban-rural comparison in prevalence of infection markers.twin seroepidemiological surveys on prevalence of hepatitis b and c virus (hbv and hcv, respectively) infection were conducted on 100 adult women in total, 50 each in the provincial capital of changchun and in a farming village in the vicinity in jilin province, northeast china. positivity to three markers on hbv (ie hbsag+, anti-hbs+, and anti-hbc+) was examined by ria methods, and to one on hcv (anti-hcv+) by eia. the results were evaluated in combination with two foregoing studies in shandong ...200011289015
[study on hepatitis g virus infection].to find out the situation of hgv infection in shandong province, and to explore the relations between hgv infection and hcv or hbv infection.199910682539
urban-rural comparison of hbv and hcv infection prevalence among adult women in shandong province, china.in order to make urban-rural comparison of the prevalence of hepatitis b and c virus (hbv and hcv, respectively) infection in china, a twin survey was conducted in 1996 on two groups (50 subjects each) of 21-55 year-old, apparently healthy women for infection markers and serum enzyme levels; one group (the urban group) was in jinan, the provincial capital of shandong province, and the other (the rural group) was in a farming village in zhangqiu area some 30 km away from jinan city. comparison be ...19979561599
direct economic burden of hepatitis b virus related diseases: evidence from shandong, china.although the expenses of liver cirrhosis are covered by a critical illness fund under the current health insurance program in china, the economic burden associated with hepatitis b virus (hbv) related diseases is not well addressed. in order to provide evidence to address the economic disease burden of hbv, we conducted a survey to investigate the direct economic burden of acute and chronic hepatitis b, cirrhosis and liver cancer caused by hbv-related disease.201323368750
seroprevalence of hepatitis c, hepatitis b virus and syphilis in hiv-1 infected patients in shandong, china.to determine the seroprevalence of hepatitis c virus (hcv), hepatitis b virus (hbv) and syphilis in hiv-1-infected patients and related risk factors in shandong province, china, we tested all eligible participants between 2000 and 2010 for the presence of anti-hcv antibody, hepatitis b surface antigen (hbsag) and non-treponemal antibodies for syphilis after informed consent. among 2087 hiv-infected patients, anti-hcv antibody was present in 41.2%, hbsag in 12.6% and rapid plasma reagin (rpr) rea ...201223033517
[hepatitis b prevalence among women in child-bearing age in shandong province, china, 2014].objective: to know the prevalence of hepatitis b virus (hbv) among women in child-bearing age in shandong province, china, providing references to the improvement of hbv control strategy. methods: the participants were randomly selected by two-stage sampling method from 12 counties which were representative for the whole province. firstly two townships were selected from each county by probability proportional to size sampling (pps) method. then participants aged 1-4 years, 5-14 years, 15-29 yea ...201728592088
comparison between two population-based hepatitis b serosurveys with an 8-year interval in shandong province, china.tremendous progress has been made in hepatitis b virus (hbv) prevention and control in the last 30 years in china, but it continues to be a major public health problem. the most recently reported population-based seroepidemiological survey on hbv in shandong province in china was published in 2006, and an updated baseline for hbv prevalence was badly needed in the province to identify the change in hbv epidemiology in the last decade.201728577994
[economic burden and related factors on inpatients with hbv-related diseases in shandong province].to investigate the economic burden of patients with acute and chronic hepatitis b, cirrhosis and liver cancer caused by hepatitis b virus (hbv).201323759235
[preliminary analysis on the prevalence and causes of breakthrough hepatitis b virus infection among children in shandong province, china].to know the prevalence and probable causes of breakthrough hepatitis b virus (hbv) infection among children born after the introduction of universal infant hepatitis b vaccination in shandong province, china.201324378135
perinatal hepatitis b prevention program in shandong province, china. evaluation and progress.post-exposure prophylaxis with hepatitis b vaccine (hepb) alone is highly effective in preventing perinatal hepatitis b virus (hbv) transmission and the world health organization recommends administering hepb to all infants within 24 h after delivery. maternal screening for hbsag and administration of hepatitis b immune globulin (hbig) in addition to hepb for infants born to hbsag-positive pregnant women can increase the effectiveness of post-exposure prophylaxis for perinatal hbv transmission. ...201425483482
cost-effectiveness analysis of a hepatitis b vaccination catch-up program among children in shandong province, china.the aim of the study was to estimate long-term cost‑effectiveness of a hepatitis b vaccination catch-up program among children born between 1994 and 2001 (when they were 8‑15 y old) in shandong province, china, to provide information for nationwide evaluation and future policy making.201425483678
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