| respiratory syncytial virus and ribavirin therapy: winter 1987-spring 1988. a report of 74 cases treated at providence hospital, anchorage, alaska. | seventy-four pediatric cases of respiratory syncytial virus lower respiratory tract infection were treated at providence hospital, anchorage, alaska between september 1, 1987 and april 30, 1988. these patients are described with illustrative case reports. twenty-one patients were treated with ribavirin and these patients are further analyzed as a special interest group. a disproportionate number of the ribavirin treated group were alaskan natives. in the discussion we address concerns of possibl ... | 1990 | 2353740 |
| hospitalizations for respiratory syncytial virus infection in alaska native children. | to characterize the epidemiology of alaska native children hospitalized for respiratory syncytial virus infections, we reviewed records of hospitalizations during the winter seasons of 1991 to 1992 and 1992 to 1993 at a hospital in anchorage and a rural hospital in the yukon kuskokwim delta (ykd) region of southwestern alaska. the median age of hospitalization for respiratory syncytial virus infection was 2 months of age for ykd residents and 4.5 months for anchorage residents. sixteen percent o ... | 1995 | 7715985 |
| association between maternal smoking and severe respiratory syncytial virus infections and sudden infant death syndrome. | | 1996 | 8936101 |
| rsv-associated hospitalizations in alaska native infants. | retrospective reviews for 1986-1992 suggested that alaska native children experience high rates of respiratory syncytial virus (rsv)-associated hospitalization; however, the epidemiology of rsv infections has been poorly characterized. | 1998 | 10093285 |
| severe respiratory syncytial virus disease in alaska native children. rsv alaska study group. | hospitalization rates for respiratory syncytial virus (rsv) infection range from 1 to 20/1000 infants. to determine the rate and severity of rsv infections requiring hospitalization for infants in the yukon-kuskokwim (yk) delta of alaska, a 3-year prospective surveillance study was conducted. the annual rate of rsv hospitalization for yk delta infants <1 year of age was 53-249/1000. rsv infection was the most frequent cause of infant hospitalization. rsv disease severity did not differ among non ... | 1999 | 10353859 |
| bronchiolitis-associated hospitalizations among american indian and alaska native children. | respiratory syncytial virus (rsv) is the leading cause of lower respiratory tract illness among infants and young children. respiratory system diseases account for a large proportion of hospitalizations in american indian and alaska native (ai/an) children; however, aggregate estimates of rsv-associated hospitalizations among ai/an children have not been made. | 2000 | 10643844 |
| respiratory syncytial virus: current status and hope for the future. | | 1999 | 10710796 |
| risk factors for severe respiratory syncytial virus infection among alaska native children. | the incidence of hospitalization for respiratory syncytial virus (rsv) infection among alaska native children is much higher than among non-native populations in the united states. we conducted this study to better understand factors associated with hospitalization attributable to rsv infection in this high-risk population. | 2002 | 11826197 |
| respiratory syncytial virus infection in navajo and white mountain apache children. | the hospitalization rate for bronchiolitis of any cause among us children younger than 1 year is estimated at 31.2 per 1000. no data exist on respiratory syncytial virus (rsv)-specific hospitalization rates among high-risk native americans other than alaska natives, for whom the incidence of rsv hospitalization was estimated at 150 per 1000 among infants younger than 1 year. we aimed to estimate rsv hospitalization rates among navajo and white mountain apache children younger than 2 years. | 2002 | 12165619 |
| impact of palivizumab prophylaxis on respiratory syncytial virus hospitalizations in high risk alaska native infants. | alaska native children experience extremely high rates of hospitalization for respiratory syncytial virus (rsv) infection. we evaluated the effect of palivizumab prophylaxis on the incidence of rsv hospitalizations in high risk alaska native children. | 2003 | 12799511 |
| bronchiolitis-associated outpatient visits and hospitalizations among american indian and alaska native children--united states, 1990-2000. | respiratory syncytial virus (rsv) is the most common cause of lower respiratory tract infection (lrti) in young children worldwide. approximately half of all lrti-associated hospitalizations are caused by bronchiolitis, with rsv accounting for 50%-80% of all bronchiolitis cases. bronchiolitis is an infection of the bronchial and bronchiolar epithelial cells, with subsequent inflammation and edema resulting in airway obstruction. this process manifests clinically as cough, wheezing, tachypnea, an ... | 2003 | 12894058 |
| sequelae of severe respiratory syncytial virus infection in infancy and early childhood among alaska native children. | in 1993-1996, we conducted a nested case-control study to determine risk factors for hospitalization with respiratory syncytial virus (rsv) infection among alaska native infants and young children. in the current study, we returned to former rsv case-patients and their control subjects during 1999-2001 to determine whether children who are hospitalized with rsv at <2 years of age are more likely to develop chronic respiratory conditions. | 2003 | 12897275 |
| early radiographic and clinical features associated with bronchiectasis in children. | bronchiectasis among children living in developing regions is associated with respiratory infections during early childhood, but specific risk factors that precede childhood bronchiectasis are not fully characterized. we hypothesized that severe respiratory syncytial viral (rsv) infection in infancy would increase the risk of bronchiectasis among alaska native children in rural alaska. this was a follow-up cohort study of a 1993-1996 case-control study of rsv-hospitalized case patients and their ... | 2004 | 15022125 |
| respiratory syncytial virus hospitalizations among american indian and alaska native infants and the general united states infant population. | to determine the burden of respiratory syncytial virus (rsv) disease among american indian (ai) and alaska native (an) infants, by examining rsv-associated hospitalizations. | 2004 | 15466069 |
| relationship between ige and specific aeroallergen sensitivity in alaskan native children. | the relationship between atopic disease and serum ige levels varies among populations and geographic regions. the close association of atopy with ige may not occur in subarctic populations as it does in developed countries in temperate climates. | 2006 | 16937753 |
| hospitalization for respiratory syncytial virus among california infants: disparities related to race, insurance, and geography. | to evaluate population-based rates of respiratory syncytial virus (rsv)-associated infant hospitalizations related to race/ethnicity, payer source, and geography in california. | 2006 | 16939750 |
| decline in respiratory syncytial virus hospitalizations in a region with high hospitalization rates and prolonged season. | during 1993 to 1996, alaska native infants <1 year of age from the yukon kuskokwim (yk) delta in alaska experienced a respiratory syncytial virus (rsv) hospitalization rate 5 times the u.s. general infant population rate. we describe trends in lower respiratory tract infection (lrti) and rsv hospitalizations in yk children from 1994 to 2004. | 2006 | 17133156 |
| respiratory syncytial virus season and hospitalizations in the alaskan yukon-kuskokwim delta. | from 1993 to 1996, alaska native infants younger than 1 year of age from the yukon-kuskokwim delta region in alaska experienced a respiratory syncytial virus (rsv) hospitalization rate 5 times higher than the u.s. general infant population rate. this article describes the trends in hospitalization and prolonged annual season of rsv hospitalizations in yukon-kuskokwim children from 1993 to 2004 and discusses factors associated with high rates of rsv hospitalization and the impact of interventions ... | 2007 | 18090200 |
| the relationship between in-home water service and the risk of respiratory tract, skin, and gastrointestinal tract infections among rural alaska natives. | we investigated the relationship between the presence of in-home piped water and wastewater services and hospitalization rates for respiratory tract, skin, and gastrointestinal tract infections in rural alaska. | 2008 | 18382002 |
| viral respiratory infections in hospitalized and community control children in alaska. | respiratory syncytial virus (rsv) in alaska native children from the yukon kuskokwim (yk) delta is associated with a hospitalization rate five times higher than that reported for the general us child population. the role of other viral respiratory pathogens has not been studied in this population. yk delta children <3 years of age hospitalized with respiratory infections and same aged community control children were prospectively enrolled between october 2005 and september 2007. polymerase chain ... | 2010 | 20513097 |
| performance of a rapid antigen test (binax now® rsv) for diagnosis of respiratory syncytial virus compared with real-time polymerase chain reaction in a pediatric population. | infants from alaska's yukon-kuskokwim delta (ykd) have a high respiratory syncytial virus (rsv) hospitalization rate (104/1000/yr). appropriate patient management requires rapid and accurate rsv diagnosis. antigen-based methods are often used in clinical settings, but these tests can lack sensitivity. | 2010 | 21163694 |
| disease complexity in a declining alaskan muskox (ovibos moschatus) population. | the muskox ( ovibos moschatus ) population inhabiting the eastern north slope (ens) of alaska, us declined dramatically during 1999-2006, whereas populations in western alaska (wa) were stable or increasing. to understand morbidity and mortality factors contributing to the decline, alaska department of fish and game conducted pathologic investigations of carcasses from 2005 until 2008. additionally, archived sera from both ens and wa muskoxen collected during 1984-92, before the documented begin ... | 2017 | 28099077 |
| risk factors for hospitalization with lower respiratory tract infections in children in rural alaska. | lower respiratory tract infections (lrtis) are a major cause of morbidity for children worldwide and particularly for children from developing and indigenous populations. in this study, we evaluated risk factors for hospitalization with lrti in a region in southwest alaska. | 2012 | 22508919 |
| association of a genetic variant of carnitine palmitoyltransferase 1a with infections in alaska native children. | to evaluate whether the arctic variant (c.1436c→t) of carnitine palmitoyltransferase type 1a (cpt1a) is associated with a higher incidence of adverse health outcomes in alaska native infants and children. | 2013 | 23992672 |
| eighteen years of respiratory syncytial virus surveillance: changes in seasonality and hospitalization rates in southwestern alaska native children. | alaska native infants from the yukon-kuskokwim delta (ykd) experienced respiratory syncytial virus (rsv) hospitalization rates 5 times higher and an rsv season twice as long as the general us infant population. we describe trends in hospitalization rates and seasonality during 18 years of continuous rsv surveillance in this population and explore contributions of climate and sociodemographic factors. | 2015 | 26065863 |