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a respiratory syncytial virus outbreak in a transitional care nursery. 1979517481
severe respiratory syncytial virus infection in older children.serious respiratory syncytial virus (rsv) disease requiring hospitalization occurs primarily in infants younger than 12 months. the incidence, risk factors, and clinical features in older children have not been studied extensively. of 282 children hospitalized at our institution with severe rsv disease during a 3-year period, 62 (22%) were older than 12 months. these 62 older children were matched for sex, onset of illness, and hospital location with 62 hospitalized children younger than 12 mont ...19902305743
validation of disease diagnoses reported to the national animal health monitoring system from a large colorado beef feedlot.clinical observation and collection of biological specimens from a large beef feedlot (approximately 30,0000 animals) were used to evaluate 6 approaches for validation of a disease reporting system. data collected during a 12-month period were used to evaluate each approach. a subsample of disease cases reported to the national animal health monitoring system (nahms) was compared with the clinical observations of the investigators. although the agreement between clinical diagnosis by the nahms v ...19883372333
isolation and serologic evidence of a respiratory syncytial virus in bighorn sheep from colorado. 19863735590
respiratory virus immunization. i. a field trial of two inactivated respiratory virus vaccines; an aqueous trivalent parainfluenza virus vaccine and an alum-precipitated respiratory syncytial virus vaccine. 19694305199
preterm twins and triplets. a high-risk group for severe respiratory syncytial virus infection.to assess the impact of multiple births and crowded homes on the severity of respiratory syncytial virus illness in preterm infants with bronchopulmonary dysplasia.19938438813
use of an internet-based community surveillance network to predict seasonal communicable disease morbidity.we designed an internet-based surveillance network that linked community clinic diagnoses with viral isolation rates and admission patterns at a related children's hospital. we hypothesized that community surveillance would successfully predict subsequent hospital admissions and laboratory viral isolations. secondarily, we expected the network to monitor trends in disease and that posting this information on a web site would be useful to physicians in daily practice.200211875134
nucleotide and predicted amino acid sequence-based analysis of the avian metapneumovirus type c cell attachment glycoprotein gene: phylogenetic analysis and molecular epidemiology of u.s. pneumoviruses.a serologically distinct avian metapneumovirus (ampv) was isolated in the united states after an outbreak of turkey rhinotracheitis (trt) in february 1997. the newly recognized u.s. virus was subsequently demonstrated to be genetically distinct from european subtypes and was designated ampv serotype c (ampv/c). we have determined the nucleotide sequence of the gene encoding the cell attachment glycoprotein (g) of ampv/c (colorado strain and three minnesota isolates) and predicted amino acid sequ ...200312682171
morbidity patterns among low-income wheezing infants.this study describes morbidity attributable to wheezing illness in a multi-ethnic sample of low-income infants younger than age 2, and examines biological, environmental, and psychosocial correlates of morbidity indexes.200312837867
microbiologic findings in feedlot cattle with acute interstitial pneumonia.to test the hypothesis that feedlot cattle with acute interstitial pneumonia (aip) have bacterial infection of the lung or liver and concurrent bovine respiratory syncytial virus (brsv) infection significantly more often than pen mates without aip animals: 39 feedlot cattle with signs consistent with aip and no history of treatment with antimicrobials and 32 healthy control cattle from the same pens.200415566091
effect of altitude on hospitalizations for respiratory syncytial virus infection.respiratory syncytial virus (rsv) infection is the foremost cause of serious lower respiratory tract infection in young children and infants. because higher rates of hospitalization for bronchiolitis and pneumonia have been noted in high-altitude regions, we hypothesized that physiologic responses to altitude would predispose children to more severe illness from rsv infection. this study examined the effect of residential altitude on hospitalizations for rsv infection in colorado from 1998 throu ...200616452353
predictors of the duration of the respiratory syncytial virus season.data from national surveillance shows significant regional variation in the respiratory syncytial virus (rsv) season. to enable accurate recommendations for surveillance and prophylaxis at a local level, we examined this variation in detail and determined predictors for the duration of the rsv season.200919710584
hospitalizations due to respiratory syncytial virus in children with congenital malformations.statewide respiratory syncytial virus (rsv) lower respiratory tract infection hospitalization data of colorado children with congenital malformations was used to estimate the population-based risk and severity of disease of rsv hospitalizations. spina bifida without anencephaly, cleft palate, lung agenesis or dysgenesis, and biliary atresia were associated with a higher risk of being hospitalized with rsv lower respiratory tract infection and an increased severity of disease when hospitalized.201121127456
down syndrome and hospitalizations due to respiratory syncytial virus: a population-based study.objective: to assess the risk estimates for respiratory syncytial virus (rsv) hospitalization in children with down syndrome (ds) and the clinical features and severity of rsv lower respiratory tract infection (lrti) in hospitalized children. study design: statewide hospitalization data for children with ds for 1995 through 2006 from the colorado health and hospital association database were combined with birth data from the colorado department of public health and environment to obtain populati ...201122177993
vaccination strategies against respiratory syncytial virus.respiratory syncytial virus (rsv) is the most common cause of us infant hospitalization. additionally, rsv is responsible for 10,000 deaths annually among the elderly across the united states, and accounts for nearly as many hospitalizations as influenza. currently, several rsv vaccine candidates are under development to target different age groups. to evaluate the potential effectiveness of age-specific vaccination strategies in averting rsv incidence, we developed a transmission model that int ...201627799521
rsv disease in the pediatric population: epidemiology, seasonal variability, and long-term outcomes.infants younger than 1 year, and especially premature infants, are susceptible to severe rsv disease, which accounts for up to 126,000 hospitalizations each year. in the united states, the rsv season generally extends from november though march, but varies considerably both temporally and geographically. studies, such as the one we have conducted in colorado, indicate that the rsv season can even vary among local communities. in addition to seasonal variability, other independent risk factors al ...200819097556
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