Publications

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[the influence of winter 2002 in pediatric health: dissociation between environmental factors and respiratory syncytial viruses, in santiago].the increase in winter related health pediatric demand is associated with three factors: cold and rainy weather, air pollution and respiratory viral epidemics. during the winter of 2002 there was, successively, heavy rain, air pollution, cold weather and a respiratory syncytial virus (rsv) epidemic in santiago.200314558245
[detection of human metapneumovirus in children hospitalized for acute lower respiratory infection in santiago, chile].human metapneumovirus (hmpv) has recently been described as a new causal agent of acute low respiratory infection (alri) in children. in south america, detection has been reported only in brazil and argentina.200516311698
role of neutralizing antibodies in adults with community-acquired pneumonia by respiratory syncytial virus.background. respiratory syncytial virus (rsv) has been implicated in the etiology of adult community-acquired pneumonia (cap). we investigated rsv infection in chilean adults with cap using direct viral detection, real-time reverse-transcription polymerase chain reaction (rtrt-pcr), and serology (microneutralization assay).methods. rsv, other respiratory viruses, and bacteria were studied by conventional and molecular techniques in adults aged ≥18 years presenting with cap to the healthcare faci ...201222238168
human respiratory syncytial virus genomic and antigenic variants isolated in two hospitals during one epidemic, in santiago, chile.human respiratory syncytial virus (hrsv) is a major cause of severe lower respiratory tract infection (lri) in children. distinct variants of the viruses have been described.200818485812
intragroup antigenic diversity of human respiratory syncytial virus (group a) isolated in argentina and chile.the intragroup antigenic diversity of the g glycoprotein of 226 human respiratory syncytial virus (hrsv) strains isolated in buenos aires (argentina) and santiago (chile) between 1995 and 2002 was evaluated by elisa with a panel of 14 anti-g monoclonal antibodies (mabs). out of 226 strains characterized, 172 (76%) belonged to group a and 54 (24%) to group b. strains from both groups cocirculated throughout the study period in both countries, except in 1996, 2000, and 2002 when only group a strai ...200516121383
adenovirus and respiratory syncytial virus-adenovirus mixed acute lower respiratory infections in chilean infants.in chile respiratory syncytial virus (rsv) and adenovirus (ad) are the principal viruses detected in acute lower respiratory infections (alri) in infants. an overview of ad pneumonia in chile to detect annual trends and to compare the severity of single ad or mixed rsv-ad infections is presented.200415071289
[influence of respiratory viruses, cold weather and air pollution in the lower respiratory tract infections in infants children].all winters, there is an increase in the number of pediatric consultations, associated to three factors: cold weather, air pollution and respiratory virus epidemics.199910752270
[hospital acute respiratory infections].to study the incidence of nosocomial respiratory tract infection along the first week after admission, 31 children under 2 years of age admitted to the pediatric wards of a general hospital at metropolitan santiago, chile, with the diagnosis of lower respiratory tract infection, were studied for viral agents by immunofluorescence tests, viral isolation from pharyngeal aspirates, paired serum viral antibodies and bacterial cultures, all of them performed at admission and 4 to 5 days later from ma ...19901965058
community- and hospital-acquired respiratory syncytial virus infections in chile.nasopharyngeal aspirates were obtained on admission from 614 patients younger than 2 years of age who were hospitalized in a ward for acute respiratory infections from june 1988 through october, 1989, in santiago, chile. patients in two rooms were followed during the cold seasons by sampling aspirates every other day during the child's entire hospital stay. clinical features were recorded daily. indirect monoclonal immunofluorescent assay and isolation in hep-2 were used for respiratory syncytia ...19911891287
genomic loads and genotypes of respiratory syncytial virus: viral factors during lower respiratory tract infection in chilean hospitalized infants.the clinical impact of viral factors (types and viral loads) during respiratory syncytial virus (rsv) infection is still controversial, especially regarding newly described genotypes. in this study, infants with rsv bronchiolitis were recruited to describe the association of these viral factors with severity of infection. rsv antigenic types, genotypes, and viral loads were determined from hospitalized patients at hospital roberto del río, santiago, chile. cases were characterized by demographic ...201728335547
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