Publications

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evolutionary pattern of human respiratory syncytial virus (subgroup a): cocirculating lineages and correlation of genetic and antigenic changes in the g glycoprotein.the genetic and antigenic variability of the g glycoproteins from 76 human respiratory syncytial (rs) viruses (subgroup a) isolated during six consecutive epidemics in either montevideo, uruguay, or madrid, spain, have been analyzed. genetic diversity was evaluated for all viruses by the rnase a mismatch cleavage method and for selected strains by dideoxy sequencing. the sequences reported here were added to those published for six isolates from birmingham, united kingdom, and for two reference ...19948057427
role of rhinovirus in hospitalized infants with respiratory tract infections in spain.rhinovirus is a recognized cause of common cold, proven to cause asthma exacerbations in children. in spain, no description exists, as yet, as to the degree of burden rhinovirus infections represent among hospitalized infants. our aim was to describe rhinovirus infections in hospitalized children, under 2 years of age, and to compare these with patients infected with respiratory syncytial virus (rsv).200717901795
ten years of global evolution of the human respiratory syncytial virus ba genotype with a 60-nucleotide duplication in the g protein gene.the emergence of natural isolates of human respiratory syncytial virus group b (hrsv-b) with a 60-nucleotide (nt) duplication in the g protein gene in buenos aires, argentina, in 1999 (a. trento et al., j. gen. virol. 84:3115-3120, 2003) and their dissemination worldwide allowed us to use the duplicated segment as a natural tag to examine in detail the evolution of hrsv during propagation in its natural host. viruses with the duplicated segment were all clustered in a new genotype, named ba (a. ...201020504933
clinical characteristics of human bocavirus infections compared with other respiratory viruses in spanish children.human bocavirus (hbov) can be found in a substantial proportion of children with respiratory tract diseases. the relative importance of hbov in viral respiratory tract illnesses is not yet well known.200818574440
[influenza virus infections in infants aged less than two years old].influenza is a major cause of respiratory tract illness in infants. the clinical characteristics of these infections are non-specific and the burden of influenza is frequently underestimated in very young children. the objective of this study was to describe confirmed influenza infections in infants < 2 years attended in a level ii public hospital. a second-rate aim was to compare influenza infections in hospitalized infants with respiratory syncytial virus (vrs) infection in the same population ...200515989867
acute respiratory disease in spain: seven years of experience.the clinical and epidemiologic features of viral and nonviral pathogens involved in acute respiratory diseases are described in the context of cases of infection (especially atypical pneumonia and bronchiolitis) studied at the centro nacional de microbiología, virología e immunología sanitarias in madrid during a 7-year period (1979-1986). these etiologies were demonstrated in 1,637 (36.2%) of 4,521 cases. among viruses, respiratory syncytial virus most frequently infected children; influenza vi ...19902237112
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