Publications

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high seroprevalence of human metapneumovirus infection in children in chongqing, china.the human metapneumovirus (hmpv) is a newly discovered respiratory viral pathogen that was first isolated in 2001 in the netherlands. its global distribution and long history of infection in humans have been well documented. in this study, we assessed the seropositivity of hmpv igg antibodies in children in chongqing, china.200819080178
[isolation of human metapneumovirus from children with acute respiratory tract infection in chongqing, china].to isolate and characterize the newly discovered human metapneumovirus (hmpv) in chongqing, china and elucidate the clinical manifestations of hmpv infection.200717349150
the genetic variability of glycoproteins among respiratory syncytial virus subtype a in china between 2009 and 2013.human respiratory syncytial virus (rsv) is the leading cause of acute lower respiratory tract infections in infants and children under 5years of age. the novel genotype on1 has a 72-nucleotide duplication, which is the largest duplicated genome portion of rsv. whether the on1 genotype will follow the pattern of the ba genotype, which has a 60-nucleotide duplication, and become the predominant rsv-a strain is a global concern. to obtain information regarding the prevalence of the on1 genotype in ...201425109878
[analysis of viral etiology of severe pneumonia in infants and young children in chongqing area].to investigate the prevalence of viral infections and putative association of viral infection with illness severity in young children with severe lower respiratory tract infection (lrti) in chongqing.201020426941
molecular characterization of human respiratory syncytial virus subtype b: a novel genotype of subtype b circulating in china.human respiratory syncytial virus (hrsv) is major pathogen of lower respiratory tract infections in infants and young children worldwide. there have been many studies regarding hrsv subgroup a (hrsv-a) g protein genetic variability but little information about hrsv subtype b (hrsv-b) g protein genetic diversity and molecular evolution in china. thus, a survey of the molecular epidemiology and evolution of the g protein in china is of high importance. in this study, the circulation and genetic di ...201524910250
genetic variability of respiratory syncytial viruses (rsv) prevalent in southwestern china from 2006 to 2009: emergence of subgroup b and a rsv as dominant strains.respiratory syncytial virus (rsv) is the most commonly identified viral agent in young children with acute respiratory tract infections (aris) and often causes repeated infections throughout life. this study investigated the genetic variability of the attachment (g) protein gene among rsv strains prevalent in southwestern china. reverse transcription-pcr (rt-pcr) for a fragment of the rsv g gene was performed with nasopharyngeal aspirates (npas) collected from children with aris hospitalized in ...201020147636
detection of viral and bacterial pathogens in hospitalized children with acute respiratory illnesses, chongqing, 2009-2013.acute respiratory infections (aris) cause large disease burden each year. the codetection of viral and bacterial pathogens is quite common; however, the significance for clinical severity remains controversial. we aimed to identify viruses and bacteria in hospitalized children with ari and the impact of mixed detections.hospitalized children with ari aged ≤16 were recruited from 2009 to 2013 at the children's hospital of chongqing medical university, chongqing, china. nasopharyngeal aspirates (n ...201525906103
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