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high human bocavirus viral load is associated with disease severity in children under five years of age.human bocavirus (hbov) is a parvovirus and detected worldwide in lower respiratory tract infections (lrtis), but its pathogenic role in respiratory illness is still debatable due to high incidence of co-infection with other respiratory viruses. to determine the prevalence of hbov infection in patients with lrti in shanghai and its correlation with disease severity, we performed a 3-year prospective study of hbov in healthy controls, outpatients and inpatients under five years of age with x-ray d ...201323638038
detection and genome analysis of human bocavirus 1-4 from hospitalized children with acute lower respiratory tract infection and symptoms of wheezing in shanghai.the aim of this study was to elucidate the clinical and molecular epidemiology of human bocavirus (hbov)1-4 in hospitalized children in shanghai suffering from acute lower respiratory tract infection with symptoms of wheezing. hbov1-4 was detected by nested pcr from 275 nasopharyngeal secretion samples collected from hospitalized children. the hbov-positive dna sequences were aligned and phylogenetic trees were constructed. the detection rate of hbov1 was 5.45% (15/275), which was second only to ...201324085194
epidemiological and clinical characteristics of respiratory viral infections in children in shanghai, china.acute respiratory tract infections (artis) due to various viruses are not only the most common causes of upper and lower respiratory infection but are also major causes of morbidity and mortality in children. in this study, we investigated the prevalence and clinical characteristics of children with virus-related artis and determined the spectrum of respiratory viruses and their correlation with meteorological variables in jiading district, shanghai, china. nasopharyngeal swabs from 2819 childre ...201627138548
genetic variation of human respiratory syncytial virus among children with fever and respiratory symptoms in shanghai, china, from 2009 to 2012.human respiratory syncytial virus (hrsv) of genus pneumovirus is one of the most common pathogens causing severe acute lower respiratory tract infection in infants and children. no information on the genotype distribution of hrsv is available in east china (e.g. shanghai). from august 2009 to december 2012, 2407 nasopharyngeal swabs were collected from outpatient children with fever and respiratory symptoms in shanghai. hrsv infection was determined using a multiplex rt-pcr assay. the second hyp ...201425046173
viral pathogens among elderly people with acute respiratory infections in shanghai, china: preliminary results from a laboratory-based surveillance, 2012-2015.acute respiratory infections (aris), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. the clinical and pathological features of elderly people with aris need to be identified for disease intervention. from january 1(st) , 2012 through december 31(st) , 2015, respiratory specimens from patients above 60 years old with aris were collected from the outpatient and inpatient settings of six ...201627943329
high incidence of multiple viral infections identified in upper respiratory tract infected children under three years of age in shanghai, china.upper respiratory tract infection (urti) is a major reason for hospitalization in childhood. more than 80% of urtis are viral. etiological diagnosis of urtis is important to make correct clinical decisions on treatment methods. however, data for viral spectrum of urtis are very limited in shanghai children.201222970251
molecular monitoring of causative viruses in child acute respiratory infection in endemo-epidemic situations in shanghai.numerous viruses are responsible for respiratory infections; however, both their distribution and genetic diversity, in a limited area and a population subgroup, have been studied only rarely during a sustained period of time.201020855230
[molecular epidemiology of human metapneumovirus in children with acute lower respiratory tract infections in shanghai.].to understand the clinical and molecular epidemiologic features of human metapneumovirus (hmpv) in children with acute lower respiratory tract infection (alrti) from oct. 2006 to feb. 2008 in shanghai.201020513294
human bocavirus in children with respiratory tract infection in shanghai: a retrospective study.human bocavirus (hbov) was first reported in 2005. the worldwide presence of hbov in children with acute respiratory tract infection (arti) has been confirmed. this study aimed to understand the prevalence and clinical features of hbov in children with arti in shanghai and explore the causative implication of hbov in arti.201020143214
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