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[meningococcal disease in spain, 1990-1997. change in its epidemiological pattern].in spain, the presentation of meningococcal disease in the 1980s was closely linked to the predominance of n. meningitidis serogroup b. this situation changed at the beginning of the 1990s, observing a growing trend of serogroup c strains in the isolation procedures carried out in some areas of the country, together with an increase in the incidence of the disease starting in the 1995-1996 season. the purpose of this study is to characterise the epidemiological pattern of meningococcal disease i ...200011031848
[haemophilus influenzae type b invasive disease and meningococcal disease: incidence and characteristics in barcelona, 1994-1995. work group ims-iuspc for surveillance and control of meningitis].the purpose of the study is to estimate the incidence of haemophilus influenzae type b invasive disease (hibid) and meningococcal disease (md) in barcelona (catalonia, spain) for the years 1994-1995.199910027177
neisseria meningitidis w-135 in the basque country, northern spain.neisseria meningitidis w-135 accounted for nine (1.6%) of 562 cases of invasive meningococcal disease and 17 (3.9%) of 430 meningococcal isolates from healthy carriers. there was no mortality associated with the invasive nine isolates, which belonged to subtype p1.6 and geno-subtype p1.18-1. all invasive isolates and 15 of the 17 isolates from healthy carriers belonged to sequence type 22 by multilocus sequence typing, and showed a similarity of > 85% by pulsed-field gel electrophoresis followin ...200616842582
Fatal Neisseria meningitidis serogroup X sepsis in immunocompromised patients in Spain. Virulence of clinical isolates.BACKGROUND: Neisseria meningitidis X (NmX) is a minority meningococcus serogroup for which no vaccine is available. Huge meningococcus X outbreaks occurred in West Africa but developed countries have reported only sporadic cases. Two invasive fatal cases are presented. METHODS: Isolates were characterized by serogrouping (latex agglutination and genogroup X-specific polymerase-chain-reaction), PorA and FetA typing, multilocus sequence typing and pulsed-field gel electrophoresis. Immunocompetent ...201122108049
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