| screening for cd8 cytotoxic t lymphocytes specific for gag of human immunodeficiency virus type 1 subtype b' henan isolate from china and identification of novel epitopes restricted by the hla-a2 and hla-a11 alleles. | the human immunodeficiency virus type 1 (hiv-1) epidemic in china is increasing rapidly at an irrepressible rate. it is caused by hiv-1 subtype b' in central china. after the full-length genome sequencing of the henan isolate was performed, the definition of optimal cytotoxic t-lymphocyte (ctl) epitopes across the henan isolate genome has become crucial for vaccine design. in this study, by using elispot assays with synthetic peptides corresponding to the sequence of the henan isolate, the ident ... | 2006 | 16361427 |