Publications

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hiv infection in healthy persons in uganda.the results of several serological surveys, carried out in uganda in the last 2 years, show that hiv infection is present in a number of different groups of individuals. there is a wide range of seropositivity (0 to 67.7%) seen within uganda. in the sexually inactive, whether primary school pupils or residents of old people's homes, no serological evidence of hiv infection was found. in young adults in kampala the hiv seropositivity ranged from 10.6 to 24.1%, whereas in rural adults the range wa ...19873126769
verbal autopsy as a tool for diagnosing hiv-related adult deaths in rural uganda.in general, information on the causes of adult deaths in developing countries is scarce. more specifically, relatively little is known about the effect of hiv-1 associated disease on adult mortality in general populations. in this study we have used a verbal autopsy technique to ascertain whether adult deaths were associated with hiv-1 in a rural population with a prevalence of hiv-1 infection of 8%, and used hiv-1 antibody status to validate the verbal autopsy findings.19968671573
the effect of human immunodeficiency virus-1 infection and stunting on measles immunoglobulin-g levels in children vaccinated against measles in uganda.measles is an important public health problem in developing nations and there is concern that immune response to measles vaccination may be compromised by paediatric human immunodeficiency virus (hiv) infection. therefore, this study investigated the relationship of immunoglobulin-g (ig-g) antibody levels in children vaccinated against measles and hiv-1 infection. further analysis was done to assess the influence of nutritional status on this relationship.199910342701
comparison of intestinal function in human immunodeficiency virus-seropositive patients in kampala and london.white homosexual men with human immunodeficiency virus (hiv) show progressive impairment of intestinal function assessed in terms of intestinal permeability and absorptive capacity. in this study we aimed to determine the effects of heterosexually acquired hiv on small-intestinal function in native africans, among whom there is a high prevalence of tropical enteropathy.199910423065
community-based trials of sexually transmitted disease treatment: repercussions for epidemiology and hiv prevention.this paper reviews the scientific basis for trials exploring the relation between sexually transmitted diseases (stds) and human immunodeficiency virus (hiv) infection in mwanza in the united republic of tanzania and rakai and masaka in the republic of uganda. the importance of a study's location and explanations for the divergent results of these trials are discussed. the modest effect on stds seen in the trial of syndromic management in mwanza, in contrast to the 38% reduction in the incidence ...200311217667
prevalence of kaposi sarcoma-associated herpesvirus compared with selected sexually transmitted diseases in adolescents and young adults in rural rakai district, uganda.kaposi sarcoma-associated herpesvirus (kshv) is transmitted by routes such as homosexual intercourse and is associated with hiv infection in industrialized countries. however, there is little information about its transmission in developing countries where kaposi sarcoma is an endemic disease.200111234789
cost-effectiveness of including tuberculin skin testing in an ipt program for hiv-infected persons in uganda.tuberculosis (tb) is the most common opportunistic infection among persons with human immunodeficiency virus or the acquired immune-deficiency syndrome (hiv/aids). isoniazid preventive therapy (ipt) effectively treats latent tb infection (ltbi) and prevents progression to active tb.200616776453
outcomes of cryptococcal meningitis in uganda before and after the availability of highly active antiretroviral therapy.cryptococcal meningitis (cm) is the proximate cause of death in 20%-30% of persons with acquired immunodeficiency syndrome in africa.200818433339
hiv-1 transmission, by stage of infection.the epidemiological impact of public health interventions targeted at reducing transmission of human immunodeficiency virus type 1 (hiv-1) during early or late-stage infection depends on the contribution of these disease stages to transmission within a particular epidemic.200818662132
geographic hiv type 1 subtype distribution in rakai district, uganda.to analyze hiv-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the rakai health sciences community cohort in uganda. portions of gag-p24 and env-gp41 were sequenced and hiv subtype was determined for 773 subjects residing in 10 community clusters in rural uganda. subtypes a (17%) and d (70%) were the most common strains in the population. subtype distribution varied by geographic region with significantly more subtype a in northern community clust ...200919803713
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