Publications

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sexual patterns and human immunodeficiency virus infection among homosexuals in taiwan.between 1988 and 1991, 64 homosexual men and 43 bisexual men were screened for human immunodeficiency virus (hiv) in southern taiwan; 5 of them were found to carry hiv antibodies. according to a self-administered questionnaire completed before screening, the average age of the men in the study group was 27 years, and the average duration of practiced homosexuality was 3.8 years. occupations included student, merchant, laborer, officer, and soldier, and many of the men (45/107) had some junior co ...19921492260
molecular subtypes of env sequences around v3 region of human immunodeficiency virus type 1 in taiwan.samples of peripheral blood mononuclear cells (pbmc) were collected during 1990-91 from seropositive healthy, male hiv-1 carriers visiting taipei venereal disease control center, and a male aids patient admitted to a general hospital. the v3 and its flanking nucleotide (nt) sequences in their dna were amplified by polymerase chain reaction (pcr) and compared with those of known hiv-1 prototypes. the nt sequences obtained from 21 individuals (e.g., tw92) clustered as group a, which were highly ho ...19947859833
needlestick and sharps injuries among health-care workers in taiwan.sharps injuries are a major cause of transmission of hepatitis b and c viruses and human immunodeficiency virus in health-care workers. to determine the yearly incidence and causes of sharps injuries in health-care workers in taiwan, we conducted a questionnaire survey in a total of 8645 health care workers, including physicians, nurses, laboratory technicians, and cleaners, from teaching hospitals of various sizes. the reported incidence of needlestick and other sharps injuries was 1.30 and 1.2 ...199910355790
determination of human immunodeficiency virus type 1 subtypes in taiwan by vpu gene analysis.the genetic diversity of human immunodeficiency virus (hiv) type 1 (hiv-1) has been characterized mainly by analysis of the env and gag genes. information on the vpu genes in the hiv sequence database is very limited. in the present study, the nucleotide sequences of the vpu genes were analyzed, and the genetic subtypes determined by analysis of the vpu gene were compared with those previously determined by analysis of the gag and env genes. the vpu genes were amplified by nested pcr of proviral ...200010878027
detection of elevated serum beta-chemokine levels in seronegative chinese individuals exposed to human immunodeficiency virus type 1.the mutations in the ccr5 coding region, such as ccr5delta32 and ccr5m303, that suppress the transmission of human immunodeficiency virus (hiv) type 1 do not exist in chinese people. however, 9 chinese subjects in taiwan with histories of multiple sexual exposures to hiv remained uninfected, suggesting that certain anti-hiv factors do indeed exist. experiments were therefore designed to investigate the immune mechanism that protects this cohort against hiv infection. peripheral blood samples fro ...200111438889
development and verification of validity and reliability of a short screening instrument to identify psychiatric morbidity.the accurate identification of minor mental disorders associated with depression and anxiety in non-psychiatric medical settings is an important component of mental health care. the present study aimed to develop a reliable and valid short screening tool to improve the identification of psychiatric morbidity.200314691593
analysis of the influence of therapy and viral suppression on high-risk sexual behaviour and sexually transmitted infections among patients infected with human immunodeficiency virus in taiwan.this study examined the effects of certain characteristics of human immunodeficiency virus (hiv)-infected patients related to the risks of practising unprotected sex (ups) among 919 hiv-infected patients who attended the sexually transmitted disease (std) clinic of the taipei city std control center, taiwan, during the period january-july 2004. after learning that they were hiv-positive, 517 (56%) subjects had practised ups, 476 (52%) had a new std diagnosis, and 106 (12%) had used some form of ...200616774563
personality traits as predictors of intentions to seek online information about stds and hiv/aids among junior and senior college students in taiwan.the purpose of this cross-sectional study is to examine how personality traits such as sensation- seeking and impulsive decision-making affect taiwanese college students' intentions to seek online information about sexually transmitted diseases (stds) and human immunodeficiency virus/acquired immune deficiency syndrome (hiv/aids). five hundred thirty-five (n = 535) junior and senior college students in taiwan were recruited and completed self-report questionnaires. this study found high sensatio ...200617034325
risk of recurrent nontyphoid salmonella bacteremia in hiv-infected patients in the era of highly active antiretroviral therapy and an increasing trend of fluoroquinolone resistance.risk of recurrent nontyphoid salmonella (nts) bacteremia and trends of antimicrobial resistance of nts remain unknown in human immunodeficiency virus (hiv)-infected patients receiving highly active antiretroviral therapy (haart).200717682981
prevalence status and association with human papilloma virus of anal squamous proliferative lesions in a patient sample in taiwan.anal squamous proliferative lesions, including condyloma, anal high-grade squamous intraepithelial lesion (ahsil) and squamous cell carcinoma (scc), are associated with human papilloma virus (hpv) infection. the objectives of the study were to investigate the hpv prevalence of anal squamous proliferative lesion in taiwan.200818650771
a pilot study of hiv education on readiness to change on substance use, aids knowledge, self-efficacy for risk reduction among male drug-dependent inmates.taiwan is experiencing an outbreak of human immunodeficiency virus infection among injection drug users. the purpose of the study was to determine the impact of a transtheoretical model-based hiv education program among drug-dependent inmates. a single group pre/post design was used to evaluate shortened impacts among 136 inmates who were arrested for illicit drug use and had attended a brief hiv education program in 2005. a repeated-measures analysis of variance indicated positive changes in ai ...200919212924
molecular epidemiology of hcv genotypes among injection drug users in taiwan: full-length sequences of two new subtype 6w strains and a recombinant form_2b6w.human immunodeficiency virus type 1 (hiv-1) circulating recombinant form (crf) 07_bc strain has caused serious outbreaks among injection drug users in taiwan since 2004. the objective of this study was to conduct a molecular epidemiological study of hcv genotypes in intravenous drug users in taiwan. blood samples and questionnaires from 591 intravenous drug users infected with hiv-1 were collected nationwide. in total, 180 samples were selected for hcv genotyping using multiplex pcr and phylogen ...201019950240
characteristics of amebic liver abscess in patients with or without human immunodeficiency virus.amebic liver abscess (ala) is the most common extra-intestinal amebiasis. this study was performed to review the clinical features of patients with amebic liver abscesses and compare them in taiwanese patients with or without human immunodeficiency virus (hiv).200920422135
cryptococcosis and tuberculosis co-infection at a university hospital in taiwan, 1993-2006.the human immunodeficiency virus (hiv) epidemic and increasing use of immunosuppressive agents have increased the prevalence of both cryptococcosis and tuberculosis (tb). however, the status of co-infection with both pathogens remains unknown.201020661622
molecular epidemiology of hepatitis d virus infection among injecting drug users with and without human immunodeficiency virus infection in taiwan.an outbreak of human immunodeficiency virus (hiv) infection occurred among injecting drug users (idu) in taiwan between 2003 and 2006, when an extremely high prevalence of hepatitis c virus (hcv) infection was also detected. to determine whether clusters of hepatitis d virus (hdv) infection occurred in this outbreak, 4 groups of subjects were studied: group 1, hiv-infected idu (n = 904); group 2, hiv-infected non-idu (n = 880); group 3, hiv-uninfected idu (n = 211); and group 4, hiv-uninfected n ...201021191061
clinical characteristics and risk behavior as a function of hiv status among heroin users enrolled in methadone treatment in northern taiwan.methadone treatment was introduced in taiwan in 2006 as a harm-reduction program in response to the human immunodeficiency virus (hiv), which is endemic among taiwanese heroin users. the present study was aimed at examining the clinical and behavioral characteristics of methadone patients in northern taiwan according to their hiv status.201121473789
comparisons of clinical features and mortality of cryptococcal meningitis between patients with and without human immunodeficiency virus infection.background: cryptococcosis is a systemic infection caused by cryptococcus neoformans, and cryptococcal meningitis can occur in patients with late-stage human immunodeficiency virus (hiv) infection and other forms of immunosuppressive status. this study was designed to compare clinical features and laboratory findings of cryptococcal meningitis in hiv-positive and hiv-negative patients. methods: from january 1, 2000 to december 31, 2009, all patients aged more than 18 years hospitalized at nation ...201121524972
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