Publications

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bluetongue in cyprus. 1975169792
brucellosis in sheep and goats in cyprus. 1979544169
q fever and animal abortion in cyprus.seventy-eight british soldiers stationed in the eastern sovereign base area (esba) in cyprus contracted q fever in the period december 1974 to june 1975. pneumonia developed in 59% of cases. of 31 patients tested, 81% had biochemical evidence of hepatitis although only one became clinically jaundiced. three patients (4%) suffered pericarditis. treatment with tetracycline had no apparent effect on the course of the disease. investigation revealed an abortion epidemic involving 21 mixed flocks of ...1977558666
the anti-echinococcosis campaign in cyprus.a national anti-echinococcosis campaign was started in 1971, in which education of the public, the control of dogs and the control of slaughter were emphasised. the campaign has already achieved almost total elimination of infection in food animals born subsequent to its initiation. stray dogs are rare and all others are registered and examined three or four times a year. infection in dogs has decreased by over 80 per cent (from 6-8 in 1972 to 1-1 in 1976). legislation governing abattoir functio ...1977910299
abortion in sheep and goats in cyprus. 1976982780
abortion in sheep and goats in cyprus caused by coxiella burneti. 1976986099
abortions in sheep and goats in cyprus. 1976997202
zoonoses in cyprus. past and present including a comment on the public health. 19761025037
scrapie in cyprus.scrapie was first recorded in cyprus in 1985 in two flocks of sheep and subsequently the disease was diagnosed in dairy goats kept in mixed flocks with affected sheep. by 1989 scrapie had been diagnosed in 23 flocks. epidemiological data presented in the present study are essentially from clinicopathological investigations between 1985 and 1989. a total of 356 out of 957 sheep and 10 out of 30 goats examined from flocks in nicosia, larnaca and limassol districts showed histopathological lesions ...19911868319
q-fever control in cyprus--recent progress. 19854027560
letter: "fog fever" in goats. 19734270652
a helminth survey of sheep and goats in cyprus. i. the seasonal distribution and prevalence of gastro-intestinal parasites. 19734270861
a helminth survey of sheep and goats in cyprus. ii. age distribution and the severity of infection with gastro-intestinal parasites. 19734751389
q fever in cyprus report of cases and a survey of united nations personnel. 19744838715
parabronema skrjabini in cyprus. 19715103996
anthrax eradication in cyprus: an historical survey. 19836346620
echinococcosis in cyprus: observations on the distribution by site of infection in sheep, cattle and goats. 19827082244
neutralising antibodies to akabane virus in ruminants in cyprus.neutralising antibodies to akabane virus, a cause of arthrogryposis and hydranencephaly, were demonstrated in serum samples from 33 sheep, 3 goats and 1 bovine among 285 serum samples collected in south-eastern cyprus from december 1970 onwards. twenty-four of the 29 sheep having positive antibodies came from one farm in liopetri. no positive sera came from animals born after 1969, no association with abortions or stillbirths was noted and no arthrogryposis or hydranencephaly was observed in cyp ...19817256874
the control of enzootic abortion in sheep and goats in cyprus. 19817284747
q fever in cyprus: a short review. 19817306776
moderate reduction of beta-globin gene transcript by a novel mutation in the 5' untranslated region: a study of its interaction with other genotypes in two families.we have identified two individuals of greek cypriot origin with thalassemia intermedia. molecular analysis has shown that each individual is a compound heterozygote for a previously described beta zero thalassemia allele and a novel mutation, c-->g in position +33, in the 5' untranslated region of the beta globin gene. in both families the beta +33 allele is associated with the same beta haplotype (-++- ) suggesting that it is likely to be of a single origin, beta-cdnas from normal and mutant be ...19968562944
control of echinococcus granulosus in cyprus and comparison with other island models.a control programme directed against echinococcus granulosus was introduced into the republic of cyprus in 1971. in 1974, this was restricted to the areas controlled by the government of the island. the force used in the 'attack' phase included a major dog control programme. this and other measures led to the rapid 'disappearance' of the parasite and control was terminated in 1985. subsequent studies during 1993-1996 revealed that the parasite was present in 82 (20%) villages in either dogs or f ...19989806495
detection and identification of the aetiological agent of mediterranean spotted fever (msf) in two genera of ticks in cyprus. 199910717741
evaluation of control programmes for echinococcosis/hydatidosis in cyprus.in cyprus, echinococcosis (echinococcus granulosus) was an important public and animal health problem until the 1970s. in 1971, the department of veterinary services instigated a control programme, which was based on an island model, using arecoline testing, euthanasia of positive dogs, control of dog breeding, elimination of stray dogs and control measures in slaughterhouses. the first programme ended in 1985 with excellent results and e. granulosus was considered to have been eradicated from b ...200011107621
a scrapie epidemic in cyprus.scrapie is endemic in the sheep flocks of many countries, but good epidemiological information on this disease is scarce. data on the initial stages of an epidemic are even more rare. we describe the ongoing epidemic of scrapie in cyprus that has been tracked since it began in the mid-1980s. the early stages of the spread of scrapie from farm to farm, between 1985 and 2000, is analysed with a simple mathematical model. the flock-to-flock basic reproductive number (r0) for the spread of scrapie w ...200415310178
novel polymorphisms at codons 146 and 151 in the prion protein gene of cyprus goats, and their association with natural scrapie.to discern whether an association exists between specific combinations of polymorphisms of the prion protein (prp) and natural scrapie in cyprus goats, 250 goats were examined, including 164 histologically positive cases. previously reported amino acid polymorphisms were detected at codons 154 (r-->h), 168(p-->q), 220(q-->h) and 240 (s-->p) and nucleotide alterations at codons 42 (a-->g) and 138 (c-->t). additionally, novel amino acid polymorphisms were detected at codons 146 (n-->s or d) and 15 ...200716314132
active surveillance of q fever in human and animal population of cyprus.a long-term active surveillance of q fever was conducted in cyprus organized in two phases.200616539741
epidemiological study of q fever in humans, ruminant animals, and ticks in cyprus using a geographical information system.a cross-sectional study of q fever was conducted in a representative sample of the human and animal population in cyprus in order to assess the seroprevalence of q fever and the prevalence of related risk factors. a total of 583 human and 974 ruminant animal serum samples were collected and tested for the detection of antibodies against coxiella burnetii phase ii antigen using an indirect immunofluorescent assay. one hundred forty-one ticks were collected from the infested animals examined; the ...200616915398
in vitro susceptibilities of brucella melitensis isolates to eleven antibiotics.brucellosis is an endemic disease present in many countries worldwide, but it is rare in europe and north america. nevertheless brucella is included in the bacteria potentially used for bioterrorism. the aim of this study was the investigation of the antibiotic susceptibility profile of brucella isolates from areas of the eastern mediterranean where it has been endemic.200617014707
[rumen ciliate, ophryoscolex purkynjei stein, 1858 (sensu göçmen, 1999) of the domestic goats (capra hircus) in northern cyprus].the ciliate protozoon that lives in the rumen of cypriot domestic goats and belongs to the genus ophryoscolex from the (capra hircus) was investigated. as the result of our investigation, a species [ophryoscolex purkynjei] including four formae [o. p. f. purkynjei, o. p. f. bifidobicinctus, o. p. f. bicoronatus and o. p. f. tricoronatus] were detected. the present study reports for the first time the presence of ophryoscolex purkynjei f. bifidobicinctus in the rumen of goats. all of the formae d ...200617160862
[morphometric variations of the rumen ciliate, ophryoscolex purkynjei stein, 1858 (ciliophora: entodiniomorphida) from cypriot domestic goats].the species ophryoscolex purkynjei and its four formae [o. p. f. purkynjei, o. p. f. bifidobicinctus, o. p. f. bicoronatus and o. p. f. tricoronatus] from the cypriot domestic goats (capra hircus) have been investigated from the viewpoint of the diagnostic morphometrical characteristics. moreover, it was demonstrated that there was significant morphometrical variations among the same formae in different host animals. as the result of our investigation, it has been suggested that all of the morph ...200617160863
prevalence of anaplasma sp. in goats and sheep in cyprus.a seroprevalence study of anaplasma infection was conducted in a stratified random sample of goats and sheep in cyprus in which the sample locations were recorded using a geographical information system (gis). the aim of the study was to estimate the prevalence of anaplasma phagocytophilum and other anaplasma species in sheep and goats, and to identify high-risk regions. a total of 689 serum samples (343 from sheep and 346 from goats) were randomly collected and tested for the detection of antib ...200918945185
acute anaplasmosis in humans in cyprus. 200919456807
design and validation of a high-throughput assay to detect codon 146 polymorphisms in the caprine prion protein gene.in sheep, scrapie susceptibility is so strongly associated with single nucleotide polymorphisms (snps) in the gene encoding the prion protein (prp) that this linkage constitutes the basis for selective breeding strategies directed toward controlling the disease. for goats, in contrast, the association between scrapie susceptibility/resistance and variations in the prp gene is far weaker, with only a few identified snps showing an influence on scrapie susceptibility. a recent survey of prp genoty ...200919559665
investigations into the cause of foot-and-mouth disease virus seropositive small ruminants in cyprus during 2007.in 2007, serological evidence for foot-and-mouth disease (fmd) infection was found as a result of differential diagnostic testing of cypriot sheep suspected to be infected with bluetongue or contagious ecthyma. seropositive sheep and goats were subsequently uncovered on ten geographically clustered flocks, while cattle and pigs in neighbouring herds were all seronegative. these antibodies were specific for serotype-o fmd virus, reacting with both structural and non-structural (ns) fmd viral prot ...200919744234
prp gene polymorphisms in cyprus goats and their association with resistance or susceptibility to natural scrapie.in contrast to scrapie in sheep, the genetic basis of susceptibility to scrapie in goats is not well understood. to study the association of prion protein (prp) alleles with susceptibility to scrapie in goats in cyprus, the coding sequence of the caprine prp gene was determined in 717 goats, including 218 scrapie positive animals. several novel polymorphisms were detected, such as a novel octarepeat variant and a stop codon mutation. amino acids at codons 146 and 154 were associated with suscept ...201120093056
rapid detection methods for viable mycobacterium avium subspecies paratuberculosis in milk and cheese.mycobacterium avium subsp. paratuberculosis (map) may have a role in the development of crohn's disease in humans via the consumption of contaminated milk and milk products. detection of map from milk and dairy products has been reported from countries on the european continent, argentina, the uk and australia. in this study three different methods (quantitative real time pcr, combined phage is900 pcr and conventional cultivation) were used to detect the presence of map in bulk tank milk (btm) a ...201020381185
q fever abortions in ruminants and associated on-farm risk factors in northern cyprus. 201121414196
spotted fever group rickettsiae in ticks in cyprus.in two surveys conducted from march 1999 to march 2001 and from january 2004 to december 2006, a total of 3,950 ticks (belonging to ten different species) were collected from seven domestic and wild animals (goat, sheep, cattle, dog, fox, hare, and mouflon) from different localities throughout cyprus. in order to establish their infection rate with spotted fever rickettsiae (sfg), ticks were pooled and tested by polymerase chain reaction targeting glta and ompa genes, followed by sequencing anal ...201121833539
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