| in vivo chloroquine sensitivity tests of plasmodium falciparum in some parts of uttar pradesh and haryana states. | | 1979 | 398332 |
| clinical profile of malaria in children--a prospective study from aligarh (n. india). | in a prospective, hospital-based study in north india, malaria accounted for 1.5% of paediatric outpatient attendances during 1 year. a marked increase in the prevalence of malaria was noted during the post-monsoon months. plasmodium falciparum was the causative species in 44.4% of cases, contrary to previous reports of low prevalence of this parasite in the area. pyrexia with or without chills or rigor, vomiting, pallor and hepatosplenomegaly were the common presenting clinical features. spleni ... | 1987 | 2441656 |
| malaria situation in meerut district villages (u.p.). | | 1986 | 2883032 |
| anopheles culicifacies: siblings species composition and its relationship to malaria incidence. | entomological and epidemiological surveys in may, august and november 1985 and march 1986 were conducted in villages in bulandshahr, a western district in uttar pradesh and in three eastern districts, jaunpur, ballia and saran. in bulandshahr, anopheles culicifacies sibling species a and b were found, with a predominance of species a. both plasmodium vivax and p. falciparum were present and the malaria incidence remained high (spr, 6-50%) indicating an active transmission. in contrast, in three ... | 1988 | 3057115 |
| susceptibility of anopheles culicifacies species a and b to plasmodium vivax and plasmodium falciparum as determined by immunoradiometric assay. | we have used a two-site immunoradiometric assay and species-specific antisporozoite monoclonal antibodies to determine the relative roles that sibling species a and b of the anopheles culicifacies complex play in malaria transmission in western uttar pradesh, india. the results unequivocally establish species a as the primary vector of both plasmodium vivax and p. falciparum in this area. our results indicate active transmission of p. vivax from may to october and of p. falciparum from august to ... | 1988 | 3068854 |
| quantitative assessment of malaria morbidity based on longitudinal data in 10 indian villages. | house-to-house visits were made at weekly intervals to investigate malaria morbidity. the survey covered 7337 individuals in 10 villages in jhansi district, uttar pradesh. incidence rates of 252 spells of sickness from fever and six symptomatic cases of malaria per 1000 population were recorded. the incidence rates of unhealthy periods due to fever, of people sick and of spells of sickness per person were significantly higher in males. morbidity from fever was highest in the 15-24 year age group ... | 1986 | 3534281 |
| the use of peptide elisa in determining malaria endemicity. | a study was undertaken with the objective to find out whether a reliable transmission index could be established by a simple peptide elisa. this would be important to evaluate the success of the bioenvironmental malaria control programmes implemented in endemic areas like the haldwani and shankargarh districts of uttar pradesh, india. we have estimated antimalarial antibodies against three synthetic peptides derived from blood stage antigens of plasmodium falciparum and against p. falciparum cru ... | 1994 | 8308272 |
| in-vivo and in-vitro sensitivity of plasmodium falciparum to chloroquine at indian oil corporation, mathura (u.p.). | in vivo and in vitro susceptibility of plasmodium falciparum to chloroquine were conducted at indian oil corporation (ioc), mathura, india. 18 out of 31 cases showed resistance [minimum inhibitory concentration (mic) 8 pmol] in in vitro study. ec50 and ec90 values estimated from log-probit analysis for resistant isolates were 0.66 and 1.44 microm/litre, and for sensitive isolates 0.28 and 0.96 microm/litre blood respectively. in vivo tests identified 13 cases (40.62%) as resistant and 19 cases ( ... | 1993 | 8319813 |
| investigation of malaria prevalence at national thermal power corporation, shaktinagar, sonbhadra district (uttar pradesh), india. | malaria in industrial complexes is promoted by extensive mosquitogenic potential generated by excavations and importation of parasite through migratory labor. the national thermal power corporation (ntpc), shaktinagar, sonbhadra district was surveyed for malariogenic conditions from 1994 to 1996. the major mosquito breeding sites were drains, storm-water drains, lakes, outside tanks, overhead tanks, sluice-valve chambers, ornamental tanks, wells, pit wells and water reservoirs, etc. anopheles cu ... | 2000 | 11414434 |
| investigation of malaria outbreak in bahraich district, uttar pradesh. | based on the reports of 139 fever related deaths in jarwal primary health centre (phc) of bahraich district, uttar pradesh (up) during april to september 1999, a study was undertaken to explore the possibility of outbreak of plasmodium falciparum malaria in the area and reasons of outbreak. | 2001 | 11968953 |
| prevalence of malaria in aligarh. | in aligarh plasmodium vivax and plasmodium falciparum infections during 1998 and 1999 were 69.6% and 62.2%, and 30.4% and 37.8%, respectively. peak transmission of malaria with highest slide positivity rates (38-44.6%) and slide p. falciparum rates (13 to 16%) were recorded during the months of september and october. about 7.5 to 10% cases showed resistance to chloroquine in p. falciparum infections while 11.3 to 16% p. vivax cases relapsed after getting required doses of chloroquine. about 75% ... | 2002 | 12718345 |
| malaria outbreak in bhojpur phc of district moradabad, uttar pradesh, india. | based on the reports of 18 fever related deaths in bhojpur primary health centre (phc) of moradabad district (up), a study was undertaken during september and october, 2000 to explore the possibility of outbreak of malaria in the area and the reasons of the outbreak. the slide positivity rate (spr) and slide falciparum rate (sfr) in active fever surveys were found to be 84.7% and 82.2% respectively. among children the average enlarged spleen and spleen rate were 1.9 and 27.4 per cent respectivel ... | 2002 | 14768829 |
| impact of residual spraying of bendiocarb against the malaria vector anopheles culicifacies in selected villages of the ghaziabad district, uttar pradesh, india. | a longitudinal study was carried out to evaluate the bioefficacy of indoor residual spraying of bendiocarb 80% wettable powder (wp) at 0.2 and 0.4 g/m2 against anopheles culicifacies, a principle malaria vector, and the impact of bendiocarb use on malaria incidence in selected villages of the ghaziabad district, uttar pradesh, india. the control village was sprayed with malathion at 1 g/m2 in 2001. two rounds of bendiocarb spraying were carried out in each year from 1999 to 2001. bendiocarb appl ... | 2004 | 15669384 |
| impact of ddt spraying on malaria transmission in bareilly district, uttar pradesh, india. | impact of indoor residual spraying of ddt on malaria transmission and vector density was evaluated in six villages of shergarh phc, bareilly district, uttar pradesh under the operational condition of national vector borne disease control programme (nvbdcp) from july 2001 to march 2002 (one transmission season only). | 2005 | 16161701 |
| prevalence of mutations associated with higher levels of sulfadoxine-pyrimethamine resistance in plasmodium falciparum isolates from car nicobar island and assam, india. | to assess sulfadoxine and pyrimethamine resistance (spr), we describe here the dihydropteroate synthetase (dhps) mutations among the plasmodium falciparum isolates in which dihydrofolate reductase (dhfr) mutations had recently been described by us (a. ahmed, m. k. das, v. dev, m. a. saifi, wajihullah, and y. d. sharma, antimicrob. agents chemother. 50:1546-1549, 2006). a majority of isolates from car nicobar island showed double dhps mutations, whereas a majority of isolates from uttar pradesh ( ... | 2006 | 16982787 |
| evaluation of malaria endemicity by peptide elisa. | interest in mapping the malaria transmission has motivated a need to develop a simple serological assay in a defined population. evaluation of coded samples by peptide elisa provided a framework to estimate the malarial impact. comparison of field data and elisa od values in different malariogenic areas shows how the disease has been more correctly interpreted. here we provide an empirical approach to estimate annual parasite index (api) as well as equivalent transmission index (eti) using a com ... | 2005 | 17080701 |
| sequence diversity and natural selection at domain i of the apical membrane antigen 1 among indian plasmodium falciparum populations. | the plasmodium falciparum apical membrane antigen 1 (ama1) is a leading malaria vaccine candidate antigen. the complete ama1 protein is comprised of three domains where domain i exhibits high sequence polymorphism and is thus named as the hyper-variable region (hvr). the present study describes the extent of genetic polymorphism and natural selection at domain i of the ama1 gene among indian p. falciparum isolates. | 2007 | 18031585 |
| characteristics of genetic hitchhiking around dihydrofolate reductase gene associated with pyrimethamine resistance in plasmodium falciparum isolates from india. | sulfadoxine-pyrimethamine (sp) resistance in plasmodium falciparum has been widespread across continents, causing the major hurdle of controlling malaria. resistance is encoded mainly by point mutations in p. falciparum dihydrofolate reductase (pfdhfr) and dihydropteroate synthase (pfdhps) target genes. to study the origin and evolution of pyrimethamine resistance on the indian subcontinent, microsatellite markers flanking the pfdhfr gene were mapped. here we describe the characteristics of gene ... | 2009 | 19786603 |
| changing trends in prevalence of different plasmodium species with dominance of plasmodium falciparum malaria infection in aligarh (india). | to determine the prevalence of malaria in aligarh and analyze species dominance in different years over a decade. | 2011 | 21771419 |