| in vitro antimicrobial activity of piperacillin/tazobactam in comparison with other broad-spectrum beta-lactams. | combining tazobactam, a beta-lactamase inhibitor, with the ureidopenicillin, piperacillin, successfully restores the activity of piperacillin against beta-lactamase producing bacteria. thus, piperacillin/tazobactam is highly active against most clinically important species of gram-negative and gram-positive bacteria, including anaerobes. we evaluated the in vitro activity of piperacillin/tazobactam against clinical isolates from a tertiary university hospital located in sao paulo, brazil. its ac ... | 2000 | 11063554 |
| multicenter evaluation of resistance patterns of klebsiella pneumoniae, escherichia coli, salmonella spp and shigella spp isolated from clinical specimens in brazil: resistnet surveillance program. | surveillance programs are essential to detect the increase of antimicrobial resistance, and several different programs are being conducted in many countries. the resistnet is a surveillance program for bacterial resistance against several antimicrobial agents initiated in 1998 among latin american countries. in brazil, several centers were invited to join this surveillance and a total of 11 centers (6 from são paulo and 5 from other states) participated in the study. all results were analyzed us ... | 2001 | 11290309 |
| multiclonal outbreak of klebsiella pneumoniae producing extended-spectrum beta-lactamase ctx-m-2 and novel variant ctx-m-59 in a neonatal intensive care unit in brazil. | an outbreak of cephalosporin-resistant klebsiella pneumoniae occurred in a neonatal intensive care unit in são paulo, brazil. of the 10 pulsotypes identified during the outbreak and follow-up periods, nine produced ctx-m-2 or its new variant ctx-m-59 and one produced shv-5. bla(ctx-m-2/59) genes were located on closely related plasmids that were transferable. | 2008 | 18347108 |
| dissemination of bla(imp-1)-carrying integron in86 among klebsiella pneumoniae isolates harboring a new trimethoprim resistance gene dfr23. | the genetic context of the bla(imp-1) gene was evaluated in 9 klebsiella pneumoniae isolates recovered from 2 hospitals in são paulo, brazil. all isolates harbored a copy of in86 carrying bla(imp-1), aac(6')-31, and aada1. eight strains from the same hospital also carried another class 1 integron harboring a new trimethoprim resistance gene (dfr23) that was chromosomally embedded. in86 was likely to be in a 30-kb nontransferable plasmid and was flanked upstream by a sequence identical to one ide ... | 2009 | 18990526 |
| prevalence and genetic characterization of blactx-m among klebsiella pneumoniae isolates collected in an intensive care unit in brazil. | thirteen (44.8%) ctx-m-2-producing k. pneumoniae clinical isolates were identified among 29 strains collected from single patients with serious infection hospitalized in an intensive care unit of a tertiary hospital located in são paulo, brazil. these isolates belonged to 9 different typing clusters and showed great diversity of plasmid content. their bla(ctx-m-2)was carried in an iscr1/sul1-type integron structure located in transferable plasmids of different sizes or in the chromosome. | 2008 | 19028623 |
| diversity of hydrocarbon-degrading klebsiella strains isolated from hydrocarbon-contaminated estuaries. | to investigate the diversity and the catabolic capacity of oil-degrading klebsiella strains isolated from hydrocarbon-contaminated sediments in santos-são vicente estuary systems in brazil. | 2009 | 19187158 |
| extended-spectrum beta-lactamases among enterobacteriaceae isolated in a public hospital in brazil. | extended-spectrum beta-lactamases (esbl) in enterobacteria are recognized worldwide as a great hospital problem. in this study, 127 esbl-producing enterobacteriaceae isolated in one year from inpatients and outpatients at a public teaching hospital at são paulo, brazil, were submitted to analysis by pcr with specific primers for bla shv, bla tem and bla ctx-m genes. from the 127 isolates, 96 (75.6%) klebsiella pneumoniae, 12 (9.3%) escherichia coli, 8 (6.2%) morganella morganii, 3 (2.3%) proteus ... | 2009 | 19739000 |
| clinical and microbiological characterization of kpc-producing klebsiella pneumoniae infections in brazil. | in 2008 isolates of kpc-producing klebsiella pneumoniae (kpc-kpn) were detected for the first time at hospital heliópolis, são paulo, brazil. the aim of this study was to characterize the clinical and microbiological outcomes of infections caused by kpc-kpn. a historical cohort of patients from whom kpc-kpn strains were isolated was performed. isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified hodge t ... | 2011 | 21412593 |
| dissemination of blakpc-2 by the spread of cc258-klebsiella pneumoniae clones (st258, st11, st437) and plasmids (incfii, incn, incl/m) among enterobacteriaceae species in brazil. | this study reports the spread of bla(kpc-2) in são paulo and rio de janeiro states facilitated by globally spread cc258-k. pneumoniae clones (st258, st11, st437) and a diversity of plasmids (incfii, incn, incl/m, two untypeable plasmids carrying tn4401a or tn4401b) successfully disseminated among enterobacteriaceae species (enterobacter cloacae, serratia marcescens and citrobacter freundii). it also constitutes the first description of st258 in brazil which was associated with a nosocomial hospi ... | 2011 | 21576442 |
| spread of carbapenem-resistant klebsiella pneumoniae in a tertiary hospital in sao paulo, brazil. | | 2011 | 21798628 |
| frequency and antimicrobial susceptibility of pathogens at tertiary public hospital, sao paulo, brazil. | nosocomial infections are one of the leading causes of morbidity and mortality. this study determined both prevalence and antimicrobial susceptibility of microorganisms identified during january to december 2012 at a tertiary public hospital, sao paulo, brazil. data, hospital length of stay, age, identity of microorganisms, and antimicrobial susceptibilities were obtained from patients' records. a total of 724 positive strains were obtained from different body sites. gram-negative microorganisms ... | 2015 | 26513931 |