| sporothrix schenckii isolated from domestic cats with and without sporotrichosis in rio de janeiro, brazil. | a total of 148 cats with a clinical and mycologic diagnosis of sporotrichosis and 84 apparently healthy cats with domiciliary contact with the affected animals were studied. sporothrix schenckii was isolated from 148 (n = 148; 100%) clinical samples of cutaneous lesion (biopsy, swab or aspiration of purulent secretion), 47 (n = 71; 66.2%) nasal cavities, 33 (n = 79; 41.8%) oral cavities, and 15 (n = 38; 39.5%) nails of cats with sporotrichosis. histopathological examination revealed yeast-like s ... | 2002 | 12000130 |
| endemic of zoonotic sporotrichosis: profile of cases in children. | sporotrichosis in childhood is rare in most countries. isolated cases and small outbreaks related to recreational activities or without identification of the transmission mechanism have been reported. | 2008 | 18277928 |
| sporotrichosis: the main differential diagnosis with tegumentary leishmaniosis in dogs from rio de janeiro, brazil. | seventy-four dogs from the state of rio de janeiro with ulcerated cutaneous lesions were submitted to clinical, dermatological, parasitological, mycological, histopathological and cytopathological exams, a leishmanin skin test, an indirect immunofluorescence (iif) test for leishmaniosis, and nonspecific laboratory tests such as blood count and serum biochemistry. sporothrix schenckii was isolated from 41 dogs and leishmania (viannia) braziliensis was isolated from 33 animals. most dogs with spor ... | 2007 | 16973286 |
| positive montenegro skin test among patients with sporotrichosis in rio de janeiro. | we studied 52 patients with sporotrichosis confirmed by isolation of sporothrix schenckii and reactivity to the montenegro skin test (mst) during an ongoing outbreak of this mycosis in rio de janeiro. the objective was to emphasize the importance of parasitological confirmation and the possibility of incorrect diagnosis based on the lesion's appearance, epidemiological information, and immunological tests. the antigen used for the mst was conserved in either thimerosal 1:10,000 (group 1) or 0.4% ... | 2005 | 15589796 |
| cat-transmitted sporotrichosis epidemic in rio de janeiro, brazil: description of a series of cases. | sporotrichosis is the most common subcutaneous mycosis in south america. classic infection is associated with traumatic inoculation of soil, vegetables, and organic matter contaminated with sporothrix schenckii. zoonotic transmission has been described in isolated cases or in small outbreaks. since 1998, we have been observing an increasing number of cases of sporotrichosis in persons from the city of rio de janeiro, brazil, and surroundings. from 1998 to 2001, 178 cases of culture-proven sporot ... | 2004 | 14765346 |
| feline sporotrichosis: epidemiological and clinical aspects. | feline sporotrichosis, which is caused by species of the sporothrix schenckii complex, is endemic to rio de janeiro, brazil. more than 4000 cases of the disease were diagnosed at fundação oswaldo cruz, brazil, between 1998 and 2012. sporotrichosis in cats has been reported in several countries, but nowhere has an outbreak of animal sporotrichosis been as large as that seen in brazil. the clinical manifestations of the disease range from an isolated skin lesion that can progress to multiple skin ... | 2015 | 25477076 |
| transmission electron microscopy analysis of skin lesions from sporotrichosis epidemic in rio de janeiro, brazil. | transmission electron microscopy can yield useful information in a range of scientific fields; it is capable of imaging at a significantly higher resolution than light microscopes and has been a very useful tool in the identification of morphological changes of the dermis as well as assessment of changes in the extracellular matrix. our aim is to characterize by electron microscopy the cellular profile of lesions caused by sporothrix schenckii from the sporotrichosis epidemic in its zoonotic for ... | 2015 | 25653392 |
| diagnostic accuracy assessment of cytopathological examination of feline sporotrichosis. | sporotrichosis is an implantation mycosis caused by pathogenic species of sporothrix schenckii complex that affects humans and animals, especially cats. its main forms of zoonotic transmission include scratching, biting and/or contact with the exudate from lesions of sick cats. in brazil, epidemic involving humans, dogs and cats has occurred since 1998. the definitive diagnosis of sporotrichosis is obtained by the isolation of the fungus in culture; however, the result can take up to four weeks, ... | 2015 | 26092106 |
| sporotrichosis in rio de janeiro, brazil: sporothrix brasiliensis is associated with atypical clinical presentations. | there have been several recent changes in the taxonomy of sporothrix schenckii as well as new observations regarding the clinical aspects of sporotrichosis. in this study, we determined the identification of the sporothrix species associated with both classic and unusual clinical aspects of sporotrichosis observed in the endemic area of sporotrichosis in rio de janeiro, brazil. | 2014 | 25233227 |
| human sporotrichosis beyond the epidemic front reveals classical transmission types in espírito santo, brazil. | sporotrichosis has emerged as the main subcutaneous mycosis of humans and animals around the world. with particular differences in frequency, the major species includes sporothrix brasiliensis, s. schenckii, s. globosa and s. luriei. in brazil, the main aspect of this epidemic is based on the zoonotic transmission through the scratches and bites of diseased cats contaminated with s. brasiliensis. areas free of feline sporotrichosis are poorly characterised in brazil. we investigated by molecular ... | 2015 | 26156862 |
| sporothrix brasiliensis outbreaks and the rapid emergence of feline sporotrichosis. | sporotrichosis is the main subcutaneous mycosis in brazil, and is caused by sporothrix schenckii and allied species. sporothrix propagules present on soil and plant debris may be traumatically inoculated into the cutaneous/ subcutaneous tissues of the warm-blooded host. an alternative route involves direct animal-animal and animal-human transmissions through deep scratches and bites of diseased cats. sporotrichosis is much more common than previously appreciated with several cases emerging over ... | 2015 | 26404561 |
| molecular identification of sporothrix species involved in the first familial outbreak of sporotrichosis in the state of espírito santo, southeastern brazil. | sporotrichosis is a widespread subcutaneous mycosis caused by the dimorphic fungi now known as the sporothrix schenckii complex. this complex is comprised of at least six species, including sporothrix albicans, sporothrix brasiliensis, sporothrix globosa, sporothrix luriei, sporothrix mexicana and s. schenckii. cases of sporotrichosis have significantly increased in brazil over the past decade, especially in the state of rio de janeiro (rj), where an epidemic among cat owners has been observed. ... | 2013 | 24141957 |
| miltefosine is active against sporothrix brasiliensis isolates with in vitro low susceptibility to amphotericin b or itraconazole. | sporotrichosis is a common mycosis caused by dimorphic fungi from the sporothrix schenckii complex. in recent years, sporotrichosis incidence rates have increased in the brazilian state of rio de janeiro, where sporothrix brasiliensis is the species more frequently isolated from patients. the standard antifungals itraconazole and amphotericin b are recommended as first-line therapy for cutaneous/lymphocutaneous and disseminated sporotrichosis, respectively, although decreased sensitivity to thes ... | 2015 | 25681323 |
| treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin b and oral itraconazole. | objective to describe the use of intralesional amphotericin b in localised lesions for the treatment of 26 cats from rio de janeiro, brazil, with sporotrichosis refractory to oral itraconazole. design uncontrolled intervention study. method the 26 cats in this study were diagnosed with sporotrichosis, confirmed by isolation of sporothrix schenckii, and presented residual localised skin lesions refractory to treatment with oral itraconazole for a minimum period of 8 weeks. the animals received we ... | 2011 | 21864307 |
| treatment of cutaneous sporotrichosis with itraconazole--study of 645 patients. | background. itraconazole has become the first choice for treatment of cutaneous sporotrichosis. however, this recommendation is based on case reports and small series. the safety and efficacy of itraconazole were evaluated in 645 patients who received a diagnosis on the basis of isolation of sporothrix schenckii in rio de janeiro, brazil. methods. a standard regimen of itraconazole (100 mg/day orally) was used. clinical and laboratory adverse events were assessed a grades 1-4. a multivariate cox ... | 2011 | 21628477 |
| molecular characterisation of sporothrix schenckii isolates from humans and cats involved in the sporotrichosis epidemic in rio de janeiro, brazil. | an epidemic of sporotrichosis, a subcutaneous mycosis caused by the fungus sporothrix schenckii, is ongoing in rio de janeiro, brazil, in which cases of human infection are related to exposure to cats. in an attempt to demonstrate the zoonotic character of this epidemic using molecular methodology, we characterised by dna-based typing methods 19 human and 25 animal s. schenckii isolates from the epidemic, as well as two control strains. to analyse the isolates, the random amplified polymorphic d ... | 2009 | 19820840 |
| histopathology of canine sporotrichosis: a morphological study of 86 cases from rio de janeiro (2001-2007). | the present study reports the histopathological findings of 86 skin lesions of dogs with sporotrichosis from rio de janeiro. suppurative granulomatous inflammation was the predominant finding and was observed in 76 (88.37%) cases. plasma cells surrounding the suppurative granulomas were detected in 68 (89.5%) cases and an inflammatory infiltrate at the periphery of these granulomatous lesions was observed in 63 (82.9%). fungus-specific staining revealed yeast cells compatible with sporothrix sch ... | 2009 | 19360480 |
| molecular epidemiology and antifungal susceptibility patterns of sporothrix schenckii isolates from a cat-transmitted epidemic of sporotrichosis in rio de janeiro, brazil. | since 1998 a cat-transmitted epidemic of sporotrichosis has been observed in rio de janeiro (rj), brazil. besides the lymphocutaneous and fixed forms, other presentations, such as disseminated cutaneous and mucosal involvement, as well as for the first time, erythema nodosum and erythema multiforme have been reported associated with sporotrichosis. this study investigates the phenotypes and genotypes of sporothrix schenckii isolates recovered from different clinical forms of the disease noted as ... | 2008 | 18324493 |
| epidemic sporotrichosis. | epidemic sporotrichosis is rare and has been related to an environmental source of infection. there were no reports of epizootics before a cat-transmitted epidemic was reported in rio de janeiro, brazil. in the present paper we review the data published on this epidemic. | 2008 | 18317034 |
| mycological evaluation of bronchoalveolar lavage in cats with respiratory signs from rio de janeiro, brazil. | twenty-three cats with respiratory signs who had domiciliary contact with cats with sporotrichosis were studied. sneezing was the predominant extracutaneous sign. twelve cats had no skin lesions and 11 had ulcerated skin lesions. mycological culture of material obtained from the nasal cavity, oral cavity, bronchoalveolar lavage (bal) and skin lesions, when present, was performed for all cats. in the case of autopsy, lung fragments were cultured. sporothrix schenckii was isolated from four of the ... | 2007 | 17472619 |
| primary conjunctival sporotrichosis: two cases from a zoonotic epidemic in rio de janeiro, brazil. | to describe sporothrix schenckii conjunctivitis in 2 owners of cats with sporotrichosis. | 2005 | 15829813 |
| sporotrichosis with widespread cutaneous lesions: report of 24 cases related to transmission by domestic cats in rio de janeiro, brazil. | sporotrichosis most commonly presents as a localized lymphocutaneous infection following traumatic inoculation of soil, vegetables or organic substrates contaminated with the dimorphic fungus sporothrix schenckii. cases of widespread cutaneous lesions are rare. there have been isolated reports of household outbreaks of sporotrichosis involving cats and humans. | 2003 | 12956676 |
| phylogenetic analysis reveals a high prevalence of sporothrix brasiliensis in feline sporotrichosis outbreaks. | sporothrix schenckii, previously assumed to be the sole agent of human and animal sporotrichosis, is in fact a species complex. recently recognized taxa include s. brasiliensis, s. globosa, s. mexicana, and s. luriei, in addition to s. schenckii sensu stricto. over the last decades, large epidemics of sporotrichosis occurred in brazil due to zoonotic transmission, and cats were pointed out as key susceptible hosts. in order to understand the eco-epidemiology of feline sporotrichosis and its role ... | 2013 | 23818999 |
| sporotrichosis: part ii. | sporotrichosis is a subcutaneous mycosis of implantation. it is the only subcutaneous mycosis for which direct examination or histology is of little or no value for diagnosis. the diagnosis solely rests on the isolation of sporothrix schenckii in culture. on pathologic examination, causative organisms are rarely seen. staining with fluorescent-labeled antibodies may aid in visualizing the cigar-shaped yeast forms; however, the organisms are still difficult to identify. topical therapy is not eff ... | 2010 | 21137636 |