| junin virus activity in rodents from endemic and nonendemic loci in central argentina. | small mammals were trapped during a 21-month period at 27 farm sites in 15 localities within and beyond the known endemic area for argentine hemorrhagic fever (ahf). prevalence of junin virus (jv) was assessed by antigen-capture enzyme immunoassay (elisa) on samples of body fluids and/or organs from 3, 282 captured rodents. infection in rodent populations was variable (0-3.7%) among localities but, in all cases, was lower than previously reported rates. overall prevalence was 1.4% in the ahf epi ... | 1991 | 1650148 |
| hantavirus infection in laboratory and wild rodents in argentina. | serum samples from urban and laboratory rats, laboratory mice and wild and laboratory cricetids in argentina were tested by immunofluorescence and plaque reduction neutralization tests to investigate prevalence of anti-hantavirus antibodies. a total of 102 sera were obtained from laboratory rodents in 4 different animal-rooms, 31 from harbor rats and 30 from wild cricetids in 1985-1987. anti-hantavirus antibodies were detected in 22.5% of rattus norvegicus in 3 of the animal-rooms but harbor rat ... | 1990 | 1981381 |
| epidemiology of argentine hemorrhagic fever. | present knowledge points to horizontal transmission as the most significant mechanism for junín virus maintenance in the main natural reservoirs, namely calomys musculinus and calomys laucha. the existence of naturally infected akodon azarae, both within and outside the endemic area, as well as the finding that other species, ecologically and phylogenetically related to the main reservoirs, such as akodon molinae and calomys callidus, can experimentally develop persistent infections with virus s ... | 1988 | 2841151 |
| experimental infection of akodon molinae (rodentia, cricetidae) with junín virus. | experimental infection with the xj-clone 3 strain of junín virus in laboratory bred akodon molinae, a cricetid rodent inhabiting the borders of endemic argentine hemorrhagic fever areas, was studied. suckling animals inoculated intracerebrally proved sensitive and became chronically infected. sixty percent of the rodents showed neurologic involvement, with mortality reaching 60%. virus was recovered from the brain at 7, 15, 21, 37, and 57 days postinfection (pi). by immunofluorescence (if), vira ... | 1986 | 3009705 |
| geographic patterns of allele frequencies in calomys musculinus reservoir-host of junin virus. | | 1986 | 3543610 |
| [present status of zoonotic hemorrhagic fevers of south america]. | since 1958, the geographical distribution of argentine hemorrhagic fever (ahf) has especially extended non only into the province of buenos aires but also towards the provinces of santa fe and cordoba, leading to an estimated population at risk of about 1.2 m inhabitants. recent epidemiological field studies has confirmed the major role of calomys musculinus and c. laucha rodents in both transmission to man and conservation of junin virus in nature. however, the human infection may result essent ... | 1993 | 7819800 |
| prevalence of infection with junin virus in rodent populations in the epidemic area of argentine hemorrhagic fever. | we report the results of indirect fluorescent antibody screening for antibody to junin virus in 1,101 sera from small mammals captured on two mark-recapture grids in the epidemic area of argentine hemorrhagic fever. twenty-six of 29 seropositive animals were the cricetid rodent calomys musculinus, for a 30-month prevalence of 7.9% in that species. combining these data with previously published data on antigen detection provided an estimated total prevalence of infection of 10.9% for this, the pr ... | 1994 | 7985747 |
| recent range expansion and low levels of contemporary gene flow in calomys musculinus: its relationship with the emergence and spread of argentine haemorrhagic fever. | the geographic distribution of haplotype diversity in the rodent calomys musculinus, sampled from 16 wild populations of argentina, was analysed on two geographical scales. the species is the natural reservoir of the junin virus, the etiological agent of the argentine haemorrhagic fever (ahf). in all, 24 composite haplotypes were recognised in the mtdna d-loop region. haplotypes 1 and 2, internal in the network, were the most frequent and were present in almost all populations. the absence of la ... | 2004 | 15316554 |
| restricted gene flow in calomys musculinus (rodentia, muridae), the natural reservoir of junin virus. | random amplified polymorphic dna polymerase chain reaction (rapd-pcr) markers were used to evaluate the relative contribution of gene flow as a determinant of the population genetic structure of the wild rodent calomys musculinus (the reservoir of argentine hemorrhagic fever [ahf]) in central argentina. one hundred eighty-seven individuals from 13 populations (9 of them from the endemic zone of ahf and 5 from areas outside it) were analyzed using 78 polymorphic rapd loci. genetic variation withi ... | 2003 | 14691315 |
| gene flow among calomys musculinus (rodentia, muridae) populations in argentina. | calomys musculinus is a sigmodontinae rodent inhabiting periodically disturbed habitats in the central eastern plains of argentina. it is the natural reservoir host of junin virus, the etiological agent of argentine hemorrhagic fever (ahf). in order to analyze the levels of gene flow among populations of this species, allozymic variability at 26 loci was studied in 291 individuals from the endemic zone of ahf and localities outside it. all populations showed high levels of polymorphism (he betwe ... | 2002 | 11990761 |
| genetic diversity of the junin virus in argentina: geographic and temporal patterns. | rna was purified from 39 strains of cell-cultured junin virus (jun) from central argentina, which included both human- and rodent-derived isolates (a total of 26 and 13, respectively), as well as from 2 laboratory jun strains, xj cl3 and xj #44. jun-specific primers were used to amplify a 511-nucleotide (nt) fragment of the nucleocapsid protein gene and a 495-nt fragment of the glycoprotein 1 (gp1) gene. genetic diversity among jun strains studied was up to 13% at the nt level and up to 9% at th ... | 2000 | 10873755 |