Publications

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aetiological studies of diarrhoeal diseases in infants and young children in iran.the aetiology of diarrhoeal diseases was investigated among 715 patients admitted to four children's hospitals in tehran, during february 1986 to march 1987, and also among 443 patients attending the central out-patient clinic in sanandaj, state of kordestan, during october 1986. enteropathogenic escherichia coli (epec) were the most common pathogens found in both areas. almost 26.7% of the patients in tehran and 20.1% of the patients in sanandaj were infected with epec. enterotoxigenic e. coli ...19902406458
genetic relatedness of clinical and environmental vibrio cholerae isolates based on triple housekeeping gene analysis.sequence analysis of dnae, hlya, and asd housekeeping genes were used to determine the genetic relatedness of our collection of vibrio cholerae isolated from patients and surface waters over a 5-year period in iran. the results showed 41, 17, and 9 variable sites throughout the sequenced fragments of dnae (837 bp), hlya (495 bp), and asd (295 bp), respectively. the results from sequence typing showed that all our clinical isolates were grouped in the same cluster. eleven genotypes were identifie ...201323397220
high prevalence of multidrug-resistant strains of vibrio cholerae, in a cholera outbreak in tehran-iran, during june-september 2008.following the occurrence of suspected cases of vibrio cholerae in karaj in 2008, this study was conducted in order to determine whether or not the cases were infected with cholera and, if so, to describe the prevalence of serotypes, route of transmission and the antimicrobial resistance profile. in this cross-sectional study, 6505 rectal swabs were collected from patients with acute gastroenteritis. serotypes and biotypes of the isolates were determined by standard procedures. the antimicrobial ...201020709810
a molecular survey on virulence associated genotypes of non-o1 non-o139 vibrio cholerae in aquatic environment of tehran, iran.thirty-seven vibrio cholerae strains were isolated from surface water sources at 5 different locations in tehran, iran during 2006 and were identified as non-o1 and non-o139 isolates. pcr for sxt element and class 1 integron was positive for 19% and 5.4% of isolates, respectively. pcr for virulence associated-genes within the vibrio pathogenicity island (vpi) gene cluster showed the presence of lj, int and rj in 8, 59 and 30% of the isolates, respectively. none of the v. cholerae isolates contai ...200919157484
molecular epidemiological study of vibrio cholerae isolates from infected patients in teheran, iran.a total of 110 clinical isolates of vibrio cholerae o1 biotype el tor serotype ogawa isolated in a recent outbreak from different districts of teheran, iran, was subjected to 99 carbon source utilisation tests, ribotyping and toxinogenotyping. pcr showed that the genes encoding cholera toxin (ctxa), toxin co-regulated pilus (tcp), accessory cholera enterotoxin (ace) and zonula occludens toxin (zot) were present in 100%, 100%, 97.3% and 99.1% of the isolates, respectively. restriction fragment le ...200011129720
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