| genetic diversity and molecular characterization of babesia motasi-like in small ruminants and ixodid ticks from china. | ovine babesioses, an important tick-borne disease of sheep and goats in china, is caused by the reproduction of intraerythrocytic protozoa of the babesia genus. babesia motasi-like is a babesia parasite that infects small ruminant in china, and two sub-groups of b. motasi-like can be subdivided based on differences in the rhoptry-associated-protein-1 gene. this study aimed to characterize the distribution, epidemiology and genetics of b. motasi-like in animals and ticks. a molecular investigatio ... | 2016 | 26976477 |
| a member of the hsp90 family from ovine babesia in china: molecular characterization, phylogenetic analysis and antigenicity. | heat shock protein 90 (hsp90) is a key component of the molecular chaperone complex essential for activating many signalling proteins involved in the development and progression of pathogenic cellular transformation. a hsp90 gene (bqhsp90) was cloned and characterized from babesia sp. bq1 (lintan), an ovine babesia isolate belonging to babesia motasi-like group, by screening a cdna expression library and performing rapid amplification of cdna ends. the full-length cdna of bqhsp90 is 2399 bp with ... | 2015 | 26156495 |
| strong conservation of rhoptry-associated-protein-1 (rap-1) locus organization and sequence among babesia isolates infecting sheep from china (babesia motasi-like phylogenetic group). | rhoptry-associated-protein 1 (rap-1) is considered as a potential vaccine candidate due to its involvement in red blood cell invasion by parasites in the genus babesia. we examined its value as a vaccine candidate by studying rap-1 conservation in isolates of babesia sp. bq1 ningxian, babesia sp. tianzhu and babesia sp. hebei, responsible for ovine babesiosis in different regions of china. the rap-1 locus in these isolates has very similar features to those described for babesia sp. bq1 lintan, ... | 2014 | 25200723 |