Publications

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proceedings of the international embryo transfer society. fifth annual conference - 14-16 january, 1979. 197933864
characterization of fort morgan virus, an alphavirus of the western equine encephalitis virus complex in an unusual ecosystem.an alphavirus isolated from nestling cliff swallows (petrochelidon pyrrhonota) and house sparrows (passer domesticus) and from cimicid bugs (oeciacus vicarius) in eastern colorado, for which we propose the name fort morgan (fm) virus, is sensitive to the action of sodium deoxycholate, unstable at ph 2.0-4.0, and demonstrates no characteristics of temperature-sensitive mutants. unpassaged field strains are nonpathogenic, or of low pathogenicity, for suckling mice; however, plaque-purified fm viru ...19807446830
use of polymerase chain reaction in an epidemiologic investigation of pontiac fever.in june 1992, 13 (38%) of 34 resort guests experienced illness that met a symptom-based case definition of pontiac fever. each ill guest reported using an indoor hot tub compared with 6 (29%) of 21 nonill guests (p < .001). water samples from the indoor hot tub were culture-negative for legionellae using standard techniques, coculture with amebae, and intraperitoneal inoculation of guinea pigs. however, polymerase chain reaction (pcr) testing of the water samples indicated the presence of legion ...19938354920
seroprevalence of and risk factors for toxoplasma gondii in the us swine herd using sera collected during the national animal health monitoring survey (swine 2006).the united states department of agriculture (usda) initiated the national animal health monitoring system (nahms) in 1983 to collect, analyse and disseminate data on animal health, management and productivity in us domestic livestock populations, including swine. the programme includes an on-farm serological sampling component which can be used to monitor seroprevalence of various pathogens, including toxoplasma gondii. the purpose of this study was to determine the seroprevalence of t. gondii i ...201019744304
spatial and phylogenetic analysis of vesicular stomatitis virus over-wintering in the united states.from 2004 through 2006, 751 vesicular stomatitis (vs) outbreaks caused by vesicular stomatitis virus serotype new jersey (vsnjv) were reported in nine states of the southwestern united states. the normal model of the spatial scan statistic and phylogenetic techniques were used to assess whether the spatial and genetic relations among vsnjv outbreaks were consistent with the hypothesis that vsnjv over-wintered in specific regions of the southwestern united states infected in 2004 and 2005, respec ...201019962205
geographic variations, cloning, and functional analyses of the venom acidic phospholipases a2 of crotalus viridis viridis.geographic venom samples of crotalus viridis viridis were obtained from south dakota, wyoming, colorado, oklahoma, texas, new mexico, and arizona. from these samples, the phospholipases a(2) (pla(2)s) were purified and their n-terminal sequences, precise masses, and in vitro enzymatic activities were determined. we purified two to four distinct acidic pla(2)s from each sample; some of them displayed different inhibition specificities toward mammalian platelets. one of the acidic pla(2)s induced ...200312623078
cardiomegaly at high altitudes: pathogenetic considerations. 19734270966
development of a syndromic surveillance system for detection of disease among livestock entering an auction market.to develop a syndromic surveillance system based on visual inspection from outside the livestock pens that could be used for detection of disease among livestock entering an auction market.200919250046
nih pre-clinical screening program: overview and current status.the increase in the number of cases of mycobacterium tuberculosis around the world has lead to a greater need for a more efficacious vaccine than the currently used m. bovis bcg. despite the relative success of this attenuated vaccine there are multiple examples where alternative strategies are desperately needed. in 1996, the national institutes of health published a request calling for applications to test newly developed vaccines against tuberculosis. the current screening program at colorado ...200515687024
emergence and re-emergence of vesicular stomatitis in the united states.vesicular stomatitis (vs) is an important disease of cattle, horses and pigs. the causal agent is an arbovirus; vesicular stomatitis virus (vsv) of which two distinct serotypes new jersey (nj) and indiana (in) have been described. the clinical signs in cattle and pigs are undistinguishable from foot-and-mouth disease (fmd), one of the most devastating viral infections of livestock. vsv is the most important cause of vesicular disease in fmd-free countries in the americas, causing thousands of ou ...200212034487
bioavailability of lead to juvenile swine dosed with soil from the smuggler mountain npl site of aspen, colorado.bioavailability of lead (pb) has become an issue in quantifying exposure of sensitive populations and, where necessary, establishing cleanup levels for contaminated soil. immature swine were used as a model for young children to estimate the degree to which pb from two fully characterized composite samples from the smuggler mountain superfund site in aspen, colorado may be bioavailable to resident children. the composite soils contained 14,200 and 3870 micrograms pb/g of soil. relative and absol ...19979143487
characterization of new jersey vesicular stomatitis virus isolates from horses and black flies during the 1982 outbreak in colorado.vesicular stomatitis viruses isolated from horses, afflicted during the recent outbreak in the western united states, and from black flies (simuliidae) were characterized with respect to the homology of their genomic rnas and the mobility of their proteins in polyacrylamide gels. all the isolates were very similar, if not identical, with respect to these two parameters. when the black fly isolate was compared to other vsv isolates, this virus appeared to belong in the hazelhurst subgroup of the ...19852997995
cured and broiled meat consumption in relation to childhood cancer: denver, colorado (united states)the association between cured and broiled meat consumption by the mother during pregnancy and by the child was examined in relation to childhood cancer. five meat groups (ham, bacon, or sausage; hot dogs; hamburgers; bologna, pastrami, corned beef, salami, or lunch meat; charcoal broiled foods) were assessed. exposures among 234 cancer cases (including 56 acute lymphocytic leukemia [all], 45 brain tumor) and 206 controls selected by random-digit dialing in the denver, colorado (united states) st ...19948167261
spontaneous mutations leading to antigenic variations in the glycoproteins of vesicular stomatitis virus field isolates.strains of vesicular stomatitis virus, new jersey serotype (vsv-nj), isolated from diseased cattle or swine were examined by genomic rna sequencing for genetic diversity potentially leading to antigenic variations in their type-specific glycoproteins as determined by reactivity with epitope-specific monoclonal antibodies (mabs). seven field isolates recovered in colorado, new mexico, georgia, and mexico during the widespread 1982-1985 epizootic in the western united states resembled the prototyp ...19901688475
heterogeneity and seroprevalence of a newly identified avian hepatitis e virus from chickens in the united states.we recently identified and characterized a novel virus, designated avian hepatitis e virus (avian hev), from chickens with hepatitis-splenomegaly syndrome (hs syndrome) in the united states. avian hev is genetically related to but distinct from human and swine hevs. to determine the extent of genetic variation and the seroprevalence of avian hev infection in chicken flocks, we genetically identified and characterized 11 additional avian hev isolates from chickens with hs syndrome and assessed th ...200212409397
scavenging by mammalian carnivores on prairie dog colonies: implications for the spread of plague.plague causes mass mortality of prairie dogs (cynomys ludovicianus) in shortgrass steppe. although the pathogen, the bacterium yersinia pestis, is spread within colonies by flea bites or contact between infected hosts, it is unclear how y. pestis is transported over long distances between isolated colonies. one possibility is that wideranging, plague-resistant mammalian carnivores pick up fleas when scavenging prairie dog carcasses. using guinea pigs as surrogates for prairie dogs, we compared h ...200918945188
epizootic vesicular stomatitis in colorado, 1982: epidemiologic studies along the northern colorado front range.epidemiologic evaluations were made of farm personnel on vesicular stomatitis-affected premises along the front range of the rocky mountains in colorado during the 1982 epizootic. a similar antibody prevalence was noted to that of veterinarians and research and regulatory personnel who were involved with the same epizootic. risk of infection resulted from intimate physical contact with infected horses or cows. incidence and infection rates in horses were 45%; rates in cows were much lower, only ...19873028193
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