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serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus.extensive serologic changes occur in systemic lupus erythematosus (sle) which are probably secondary to unknow primary cause(s). the new zealand hybrid mouse model most likely has a viral-induced disease and does not show many of the clinical features of the human disease. the best example of human sle which provides a clue to etiology is the drug-induced type, particularly that due to procainamide. in these patients it is possible to study the development of serologic changes prior to the onset ...197550452
naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class.a new class of murine leukemia viruses, isolated from wild mus musculus trapped in california, is described. these viruses, designated "amphotropic," replicate in mouse, rabbit, mink, human, guinea pig, and rat cells, but not in hamster, quail, or duck cells. they show n-tropism for mouse cells, and do not trigger the xc cell response. they are distinct by interference and virus neutralization testing from the previously recognized mouse-tropic and xenotropic mulv classes. mouse-tropic viruses o ...197659816
patterns of sexually transmitted enteric diseases in a city.in the past three years cases of shigellosis, amoebiasis, and viral hepatitis a and b have increased fourfold to tenfold in san francisco. these diseases were most common in people who had adopted "alternative life-styles", especially in young men, in many cases there was a history of frequent orogenital and oral-anal sexual contact between men with no common source. despite energetic public-health measures and intensive efforts by physicians treating these cases, the increase has not yet been b ...197769111
co-circulation of two influenza a (h3n2) antigenic variants detected by virus surveillance in individual communities.from march through june 1977 a total of 31 influenza a (h3n2) viruses were isolated from students with respiratory disease who were seen at the student health service on the berkeley campus of the university of california, and 32 influenza a (h3n2) viruses were isolated from persons who participated in a city-wide febrile respiratory disease surveillance program in seattle. the antigenic specificity of the hemagglutinin was determined for each isolate by hemagglutination inhibition testing with ...197883107
a serologic survey of mule deer and elk in utah.sera from mule deer (odocoileus hemionus) and elk (cervus canadensis) in central and northern utah were tested for the prevalence of antibodies to 11 diseases communicable to man or domestic livestock. antibodies to francisella tularensis (at 1:20) were found in 47 of 88 (53.4%) elk and 1 of 89 (1.1%) deer. a screening slide agglutination test for titers to brucella (at 1:20) showed two reactors in elk but none in deer sera. no positive antibody titers were obtained in tests for anaplasmosis, co ...1978105153
diocytophymatid larval nematode in a subcutaneous nodule from man in california.a nematode in a subcutaneous nodule excised from the chest of a man in central california is described and identified as a third-stage larval dioctophymatid, probably dioctophyma renale, though a eustrongylides species could not be excluded. in all well-documented previously reported cases of d. renale infection in man, none of which was from north america, adult worms were discovered in the kidney at autopsy (5 cases), or were observed migrating or being expelled through the urethra (6 cases), ...1979156507
occupational exposures to pesticides containing organoarsenicals in california.the only organic arsenicals used in agriculture are methanearsonic acid (msma) and its sodium and ammonium salts and dimethylarsinic acid (cacodylic acid) and its sodium salt. they have an oral ld50 in the rat of 700-1,000 mg/kg and are classified as toxicity category 3 pesticides. during the three-year period 1975, 1976 and 1977 in california there were 34 reports by physicians of injury due to exposure to pesticides containing organic arsenicals of which nine resulted in systemic symptoms and ...1979161110
epidemiologic study of a leukocyte-transforming agent in a general population.studies by others have demonstrated a leukocyte-transforming agent(s) (lta) in the oropharyngeal secretions of a significant number of individuals with epstein-barr virus-associated infectious mononucleosis, cancer, and, to a lesser extent, an outpatient population. this present study determines by systematic sampling the prevalence of lta in 27 families of a semirural community. throat swab inoculums from three of 54 adults and none of 44 children induced transformation of umbilical cord lympho ...1975173738
amphotropic host range of naturally occuring wild mouse leukemia viruses.seven murine leukemia virus field isolates (uncloned) from wild mice (musmusculus) of four widely separated areas in southern california show an unusually wide in vitro host range. they replicate well in human, feline, canine, guinea pig, rabbit, rat, and mouse cells, whereas bovine, hamster, and avian cells are resistant. since this host range includes that of both mouse tropic (ecotropic) and xenotropic murine leukemia viruses, they are designated as "amphotropic". no purely xenotropic virus c ...1976181592
some secular changes in the growth of american-born and native japanese children.three hundred and sixteen (35%) of the american-born japanese children whose height, weight, and skeletal age were recorded in 1956-57 were reexamined as young adults between 1968 and 1974, when they were found to be taller, heavier and shorter legged than men and women in japan who were born in the same years as they. these differences between the american-born and the native japanese adults were relatively smaller than they had been during childhood, due to both an acceleration in the growth r ...1976187065
primary epstein-barr virus infections in children.during a serioepidemiologic survey of a community, 13 (6.2%) of 209 children were found to be experiencing a current or recent primary epstein-barr virus (ebv) infection. the sera contained elevated antibody titers to viral capsid antigen of ebv, antibodies to early antigen (ea) of ebv, and specific igm. the frequency of primary infections was highest in the first decade of life. the primary ebv infections were usually asymptomatic. the antibody to ea was directed predominantly to the r componen ...1977190581
viral hepatitis: enzyme assays and serologic procedures in the study of an epidemic.an epidemic of viral hepatitis beginning in late 1975 in a residence for multiply handicapped children, recognized very early in its course, was investigated prospectively to permit comparison of enzymatic and serologic tests. thirty-three residents of the institution and 46 full- and part-time employees were studied by the immune adherence hemagglutination procedure for antibody (anti-hav) to hepatitis a virus (hav). of these, 31 residents and 37 staff members were susceptible at the beginning ...1977201170
tonsillectomy and infectious mononucleosis.tonsillar tissue may be the primary site of infection with epstein-barr virus (ebv), the etiologic agent of classical infectious mononucleosis (im). therefore, a retrospective study of the association between tonsillectomy and im was performed in a college student population. in the first part of the study, tonsillectomy rates were compared between 164 im-positive students and 164 student controls who attended ucla in 1972-1975. although it was determined that the development of im during colleg ...1978203187
selected observations on the epidemiology of pharyngeal cancers.the epidemiology of nasopharyngeal cancer (npc) has been compared with that of other pharyngeal cancers in los angeles county. epstein-barr virus (ebv) antibody titers were elevated in caucasians with pharyngeal squamous cell carcinomas regardless of subsite. as expected, an excess of npc cases was found among chinese. the role of various etiologic factors in npc including ebv, inhaled carcinogens, and salted fish was discussed.1977206840
venereal aspects of gastroenterology. 1979218367
comparative pathology of silicate pneumoconiosis.a simple pneumoconiosis with lamellar birefringent crystals was observed in animals dying in the san diego zoo. we studied 100 autopsies from 11 mammalian and eight avian species. in mammals, mild pulmonary lesions comprised crystal-laden macrophages in alveoli and lymphatics. interstitial fibrosis was present in 20% of cases. there were no nodules. in birds, dust retention produced large granulomas around tertiary bronchi without fibrosis. mineralogic analysis using scanning and transmission el ...1979223447
incidence of infectious mononucleosis at the universities of california and hawaii.the observed rates of heterophil-positive infectious mononucleosis at the university of california at davis and the university of hawaii at manoa were 1,212 and 37 per 100,000 students per academic year, respectively. the data collected suggest that the extraordinarily low incidence at the university of hawaii may be due to the following factors: (1) underutilization of the student health service by students with infectious mononucleosis; (2) low proportion of epstein-barr virus-seronegative stu ...1979229170
the feds are coming. 1977274196
dental caries and trace element composition of whole human enamel: western united states.samples of whole enamel prepared from 83 teeth were analyzed for the concentrations of 30 trace elements. samples were from lifelong residents, younger than 20 years of age, of a high-caries area (oregon) and a low-caries area (california). all samples were caries-free, prepared by standardized methods, and analyzed by spark source mass spectrometry by one laboratory. elements strongly associated with a high prevalence of caries were copper, and, to a lesser extent, aluminum, sulfur, titanium, c ...1978274496
control of graft arteriosclerosis in human heart transplant recipients. 1977320695
an evolving pattern of human hydatid disease transmission in the united states.echinococcus granulosus infection was being acquired in the contiguous united states by virginia sharecroppers and small-holders by the turn of the century. the last recorded human infection from that general area was diagnosed in 1947. by 1920 human infections were also being acquired in the lower mississippi valley. apparently, infection in both of these areas was maintained chiefly in swine. by 1940 a third transmission area definitely existed in the central valley of california, with its res ...1977329700
health care cost containment experiments: policy, individual rights, and the law.in a climate of increasing pressure to contain health care costs, legislators and health services researchers from time to time have proposed experiments involving reductions in benefits currently authorized under the medicare and medicaid programs. this paper examines three court challenges to the conduct of such experiments in california, new york, and georgia. the rulings on the california and new york cases were in favor of continuing the experiments on the grounds that the secretary of heal ...1978365931
the limits of excellence: what one man can do. first annual niels bjorn jorgensen memorial lecture. 1978373510
rudolf schindler, pioneer endoscopist. glimpses of the man and his work. 1979376393
epidemiologic survey of sylvatic plague by serotesting coyote sentinels with enzyme immunoassay.the geographic distribution and areas of high sylvatic plague activity in california were verified by using coyotes (canis latrans) as sentinel animals. antibody levels against yersinia pestis were tested using the enzyme-labelled antibody (ela) test and the microtiter passive hemagglutination and hemagglutination inhibition. a survey using the ela test indicated that the overall antibody prevalence among 143 coyotes was 21%. by geographic regions, the highest antibody prevalence was 27% among c ...1979382839
[chemical synthesis of human insulin gene and its expression in the cells of escherichia coli]. 1979388393
social networks, host resistance, and mortality: a nine-year follow-up study of alameda county residents.the relationship between social and community ties and mortality was assessed using the 1965 human population laboratory survey of a random sample of 6928 adults in alameda county, california and a subsequent nine-year mortality follow-up. the findings show that people who lacked social and community ties were more likely to die in the follow-up period than those with more extensive contacts. the age-adjusted relative risks for those most isolated when compared to those with the most social cont ...1979425958
epidemiologic and clinical aspects of animal bite injuries.during 1975, 332 animal bite injuries accounted for 1.2% of all surgical problems treated at the ucla hospital emergency department. data on 307 bite injuries were available and analyzed for environmental, animal, human, interaction, and clinical factors. more than half of the dog bites and almost three fourths of the cat bites-scratches happened at or near the victims' homes. dog bites were almost twice as common among men, while cat bites-scratches were twice as common among women. of the inci ...1979430939
human services workers: a study of perceptions of their role.human services workers at the veterans administration hospital, brentwood, are involved with patients from the time they are admitted to the hospital until they are discharged and adjust to the community. as part of an evaluation of their role, a study was done of their tasks as perceived by themselves, by their supervisors, by other paraprofessionals, and by patients. in general, human services workers were perceived to be most involved in assisting patients in the hospital, followed by involve ...1979447232
correlation of culex tarsalis population indices with the incidence of st. louis encephalitis and western equine encephalomyelitis in california.mosquito population indices from california for the period 1953-1973 were analyzed to determine their association with activity of st. louis encephalitis (sle) and western equine encephalomyelitis (wee) viruses. culex tarsalis female populations, as measured by new jersey light trap indices (lti), correlated positively with the incidence rates of encephalitis in humans, and were a reliable means of forecasting the years of highest incidence. the critical level of c. tarsalis in urban areas below ...1979453436
research and experimentation in hospitals. 1979468176
association between raw milk and human salmonella dublin infection.between 1971 and 1975 the mean annual incidence of human salmonella dublin infection in california increased more than five-fold. investigation of the increase showed an association with exposure to raw milk in 44 out of 113 cases. of these 44 patients, 35 had used certified raw milk from a single dairy. faecal swabs confirmed s dublin infection in the dairy herd and the milk, and so a pasteurisation order was issued. s dublin appears to be an unusually invasive and life-threatening salmonella s ...1979476402
government regulations on lens implantation. 1979489459
poisoning of man and animals due to ingestion of the rodent poison, vacor. 1979494485
symptomatic coccidioidomycosis following a severe natural dust storm. an outbreak at the naval air station, lemoore, calif.eighteen newly diagnosed cases of symptomatic cocidioidomycosis developed two to four weeks following exposure to a severe natural dust storm. the population at risk consisted of 26,000 residents of the san joaquin valley with access to health care at the naval hospital, lemoore, calif. eight patients were white, and ten were nonwhite. the number of cases per 100,000 was estimated to be 36 for the white group and 254 for the nonwhite group. the disease was disseminated in four patients, and all ...1979498830
arsenic levels in human blood, urine, and hair in response to exposure via drinking water. 1979499171
sales of nonprescription cold remedies: a unique method of influenza surveillance.in 1976, the national institute of allergy and infectious disease sponsored a nationwide network for influenza surveillance. in this paper, in addition to reporting the surveillance findings in los angeles, sales of nonprescription cold remedies in a large supermarket chain were evaluated as an indicator of influenza activity in the community. twenty-seven isolates of influenza b occurred between february 17 and april 26, 1977. peak influenza b activity occurred from mid-march to early april, 19 ...1979503653
human intestinal parasites in a farm community. 1979506225
yersiniosis in california.thirty-three strains of yersinia enterocolitica representing 11 different serotypes were identified from human isolates in california between 1968 and mid-1977. the most frequently encountered serotype, 0:5,27, was identified in 8 cases. twenty-one strains, representing five serotypes, were esculin- and salicin-negative, and were considered to be the primary cause of disease in the majority of these cases. the remaining strains, representing six serotypes, were esculin- and salicin-positive, and ...1979535374
trichinosis in bears of western and northcentral united states.black bears (ursus americanus) from 10 states were examined for trichinella spiralis during the 1970-1975 period. trichinae were found in 14 (3.1%) of 454 bears examined. infected bears were found from california, seven (13.2%) of 54; idaho, one (2.3%) of 44; and wisconsin, six (3.8%) of 163. trichina counts per gram of tissue obtained by the artificial digestion-baermann method ranged from 1390 to 0.02. six california bears and one from wisconsin contained more than one trichina per gram, a lev ...1977560797
guidelines for defining and disposing of medical waste.considerations of ecology, public health hazards, and rising health costs have been critically reevaluated in the matter of appropriate medical waste disposal at nursing homes and hospitals. the maryland department of health has intermittently received reports from the public of human tissues, bandages, and other inappropriate, unaesthetic materials visible in landfill areas. the department has experienced increasing concern for communicable disease transmission, e.g. hepatitis, to landfill wast ...1978623571
erythema chronicum migrans in america.erythema chronicum migrans (ecm) developed in a man after a tick bite; the tick was probably lxodes pacificus. despite extensive laboratory evaluation, including bacterial culture of involved skin, viral and rickettsial titers, biopsy and special stains, animal inoculation, and electron microscopy, the causal agent could not be identified. although probably unrelated, an elevated measles titer with a twofold drop on serial determinations was of interest. to our knowledge, this report documents t ...1978629552
right-to-die laws: creating, not clarifying, problems.that living will, or natural death, legislation--which is currently being pushed in state assemblies nationwide--is unnecessary and may actually inhibit physicians in providing the best of care to dying patients is evident from an analysis of the statutes that have been passed. whether the motivation behind such legislation is to take a step toward legalizing euthanasia is an open question.1978649133
clinical aspects of sperm bank.the ability to preserve human sperm by cryogenic methods has been developed and successfully applied to reproductive biology. some of the advantages include 1) availability of sperm for heterologous (donor) insemination, 2) accumulation of multiple oligospermic specimens for homologous (husband) insemination, 3) preservation of sperm prior to vasectomy, 4) collection and preservation of sperm from men who face permanent injury to spermatogenesis through an operation, chemotherapy or radiation, 5 ...1978650756
informed consent by children and participation in an influenza vaccine trial.two hundred thirteen school children, ages six to nine, were presented the opportunity to participate in an experimental trial of swine influenza vaccine. in non-directive question and answer sessions, all groups of children except one composed only of six year olds elicited all relevant information on the details of the trial and the associated risks and benefits. forty-six per cent of the subjects declined to participate. letters requiring informed consent of the parents were sent to the homes ...1978717615
dying right in california--the natural death act. 1978747909
human births and the phase of the moon.published studies on the frequency of births as related to the lunar cycle are inconsistent with each other. the distribution of all births during 51 lunar cycles, from march 17, 1974, to april 30, 1978, was analyzed by the authors at the university of california, los angeles, hospital. there were 11.691 live births, of which 8142 were natural, 141 multiple, and 168 stillbirths. in none of the 4 samples was the mean number of births occurring on the date of the full moon above average, showin ...1979758594
politics, legislation, and natural death. the right to die in california. 1976786948
an areawide cancer reporting network.a cancer surveillance program was formed in 1970 to provide a mechanism for the early identification of some 22,000 cancer cases that are diagnosed annually among the large and varied population of los angeles county. the program's rapid reporting procedures facilitate early access to patients for interviewing and specimen collection. routine review of all reports of microscopically diagnosed malignancies in hospitals throughout the county and screening of all of the county's death certificates ...1975803690
vigorous medical management of acute fulminant hepatitis.twenty patients with acute fulminant hepatic failure and stage ii, iii, or iv hepatic encephalopathy attributable to viral hepatitis were studied to assess the risk factors, as well as the affects of vigorous medical management. these patients were treated according to a protocol that directed aggressive medical management of fluid balance with electrolyte solutions, plasma, and blood; acid-base balance; coagulation defects with fresh frozen plasma; blood replacement as needed; dietary protein e ...1977856088
role of midwives.dr. alfano (new england journal of medicine 296: 1126, 1977) is certainly entitled to his personal opinions, but when they appear in a major publication in a setting that calls for factual information, they cannot go unchallenged. midwives have played and continue to play a major part in maternal-infant services in many advanced european countries. combined midwife-physician services in sweden, finland, japan, netherlands, denmark, norway, and switzerland produced infant mortality rates in 19 ...1977876307
biomedical experimentation on prisoners. review of practices and problems and proposal of a new regulatory approach. 1977885130
magnitude of lead intake from respiration by normal man.lead metabolism of five normal men was studied in a hospital metabolic unit in order to measure the daily intake of lead by respiration in urban adults. subjects ingested a constant diet, and samples of blood, urine, feces, and diet were analyzed periodically for lead isotopic abundances by mass spectrometry. three men were fed daily a stable isotope tracer of lead for 83 to 124 days in order to distinguish ingested from respired lead. also, three men lived in rooms with filtered, low-lead air f ...1977886210
the ombudsman: a serendipitous mental health intervention.it is proposed that the ombudsman program, originally conceived of as a protection of the political rights of individual citizens, can be profitably viewed as a primary prevention of psychological disorders. the ombudsman attempts to alleviate reality problems prior to the onset of psychological disruption by engaging in active change agentry in public and private bureaucracies. two hundred randomly selected written complaints were analyzed to ascertain the types of problems brought to this prog ...1977913080
editorial: labeling human blood: an ominous sign? 1976933198
relating influenza epidemics to childhood leukemia in tumor registries without a defined population base: a critique with suggestions for improved methods. 1976937337
student health advocates: a program for extending health services to ucla students. 1976950410
unusual three-dimensional bite mark evidence in a homicide case.a comparison has been made between bite marks observed on the nose of a female homicide victim and the configuration of the dental structures of a male suspect. the victim's bite marks showed a number of demonstrable characteristics which could be reproduced by models of the dentition of the suspect. special peculiarities within and between individual teeth, together with the upper and lower jaw relationship, were demonstrably consistent with the bite mark patterns on the victim's nose. detailed ...1976956753
distribution of suspected tick vectors and reported cases of rocky mountain spotted fever in california.evidence is presented for an area of human risk to rocky mountain spotted fever (rmsf) in california extending beyond the range of its classic tick vector, dermacentor andersoni. geographic, seasonal, and host distributions of dermacentor variabilis and dermacentor occidentalis suggest these species as potential vectors of rmsf in california outside the range of dermacentor andersoni.1976961695
yersinia enterocolitica isolates from humans in california, 1968-1975.this paper reports on the serological and biochemical characteristics of 24 human isolates of yersinia enterocolitica submitted to the california department of health from 1968 through 1975. nine different serotypes were represented. the majority of strains were serotype o:8 (six strains) and serotype o:5 (five strains). sources of the isolates included feces (12 cases), blood (3), sputum or throat (3), bile or bowel drainage (2), wounds (2), breast abscess (1), and skin abscess (1). clinical hi ...1976965477
the unwanted child: caring for the fetus born alive after an abortion. 1976972026
the allergic theory of radiocontrast agent toxicity: demonstration of antibody activity in sera of patients suffering major radiocontrast agent reactions.an allergic, immunologic mechanism for certain adverse reactions to radiocontrast agents has been postulated on the basis of clinical and theoretical considerations. one obstacle to the acceptance of this allergic theory has been the inability to demonstrate significant antibodies with specificity for these agents. in our studies, rabbits were immunized with 4 analogues of radiocontrast agents which induced igg or ige antibodies specific for the contrast media analogues. then, to determine if an ...1976977260
the bcg for measuring cardiac output in a california gray whale.resting cardiac output can be predicted reasonably accurately from body mass in man and other mammals. we measured the stroke volume of a 4,500-kg whale and found that iberall's formula holds true even when body mass is very large. in addition, the bcg acceleration trace and cardiac indices were remarkably similar to those of 20-gram and 70-kg mammals, mouse and man.1976985341
veterinary surgeons in zoological medicine.to be successful in zoo work veterinary surgeons must alter their approach and acquire a basic philosophy of concern for wild species. with proper motivation and background information and a good biological outlook, they would be in a unique position to solve problems essential to the continued existence of some species of wild animals and the betterment of human life. veterinary schools will have to make a concentrated effort to give students an opportunity to explore the nature of the problems ...1976988668
treatment or mistreatment in psychiatry (observations on electroconvulsive therapy). 1976991719
the devil's advocate. 19761027513
student views of human services delivery in florida. 19761028626
student views of human services delivery to florida. 19761028627
studies in adaption to ambient oxidant air pollution: effects of ozone exposure in los angeles residents vs. new arrivals.to test the hypothesis that adaptation protecting against acute effects of ambient ozone (o3) exposures develops in los angeles residents, human volunteers were exposed to 0.4 ppm o3 under conditions simulating ambient pollution exposures. blood biochemical, pulmonary physiological, and clinical responses were assessed. los angeles residents (n = 6) showed only minimal clinical or physiological response to o3, while new arrivals (n = 9) showed significant losses in pulmonary function and a tende ...19761030397
"ischemic" heart disease in fire fighters with normal coronary arteries.near maximal stress testing conducted on a group (n = 90) of randomly selected los angeles city fire fighters (age 40-59 yrs.) revealed that 10% had ischemic ecg changes. these ischemic ecg responses were confirmed during a second test conducted two to four weeks after the initial test. coronary heart disease (chd) risk factor analysis revealed that in general the men were not at high risk for chd. six of the nine men elected to undergo cardiac catheterization and angiography. one patient had se ...19761032966
increasing nursing students' interest on working with aged patients.the tuckman-lorge attitude questionnaire, which measures stereotypes and misconceptions about the aged, was administered to 311 baccalaureate nursing students who were also asked to indicate their relative preferences for various fields of specialization within nursing and their preferences for working with child, adult, and elderly patients. the study was designed to examine factors--a two-semester course in human development and aging, visits with a physically "well" older person living in the ...19751038016
helping the community accept human sexuality content in a high school curriculum: the case of pomona. 19761043980
does human maternal behaviour after delivery show a characteristic pattern?specific kinds of maternal behaviour such as nesting, retrieving, grooming and exploring, are seen in non-human mammalian mothers immediately before, during and after delivery. in this study 22 human mothers were filmed during the first 10 minutes of contact with their normal nude full-term infants, who were placed beside them in private rooms in hospitals in guatemala and the us; and nine mothers of premature infants were filmed on their first three visits to the nursery. another 10 guatemalan ...19751045987
excess leukemia in cohorts of children born following influenza epidemics.two series of data from the california state department of health and one from children's hospital of los angeles were analyzed to determine whether an association exists between influenza epidemics and incidence of leukemia in children born following such outbreaks. of leukemic children born in areas for which information on past influenza activity was available, the population-based alameda county cancer registry recorded 89 cases during 1960-1969, the california tumor registry recorded 653 ca ...19751054535
scanning electron microscopy of dentition: methodology and ultrastructural morphology of tooth wear.scanning electron micrographs were taken of sets of human molars-those of paleo-indians used in mastication of, ostensibly, a highly abrasive diet, and those of contemporary americans. different ultrastructural patterns of enamel wear were observed between the groups.19751090642
the status and dilemma of human transplant tissue procurement in the united states--a solution. 19751124566
letter: acute transient myositis with influenza-like illness. 19751133667
arbovirus surveillance in florida: wild vertebrate studies 1965-1974.wildlife species from 38 of florida's 67 counties were surveyed over a 10 year period for the presence of antibody to the five major arboviruses circulating in the state. the routine screening of 7891 sera from wild birds and mammals via the hemagglutination-inhibition (h1) test with selected reactors subjected to serum neutralization testing has 1) provided information regarding geographic distribution and seasonality of circulation of these viruses 2) identified enzootic foci of infection and ...19751152173
genetic analysis of cover test measures and ac/a ratio in human populations with varying incidences of strabismus.the genetic analyses of indices relating to distance alignment and accommodative convergence are presented. this approach is important in understanding the contribution of genetic factors to observed individual differences for these measures. abnormalities of either of these two components results in a tendency towards either a convergent or divergent position of the eyes (relative to the position of fusional demand) and thus places an additional load or strain on the other components of the bin ...19751191623
temporary human infection with a phocanema sp. larva. 19751200259
methods of spread of velogenic viscerotropic newcastle disease virus in the southern californian epidemic of 1971-1973.data collected during the velogenic viscerotropic newcastle disease (vvnd) epidemic that occurred in southern california from 1971 to 1973 were analyzed to determine the methods of spread of the disease. spread between chicken flocks was extensive and due mainly to the movement of live birds and mechanical transport of virus by man, especially by vaccination and poultry service crews. spread to exotic birds was from contact with infected imported stock. spread to other species was most probably ...19751200943
erythraemia due to haemoglobin san diego.a 63-year-old man with erythraemia was found to have a high affinity haemoglobin which was subsequently identified as hb san diego beta 109 (g11) val leads to met, recently described in a filipino family (nute et al, 1974). the oxygen affinity of the haemolysates was increased approximately two-fold at ph values between 6.04 and 7.90. the n value was nearly normal (2.5-2.9) in the upper range of saturation (70-95% oxygenation) but was somewhat diminished (1.9-2.1) below this range. in vitro bios ...19751201208
recent legal-psychiatric developments in california. 19751230187
[computerized patient-monitoring in the o.r (author's transl)].the routinely performed data-aquisition and its analysis by means of a computerized patient-monitoring-system will reduce the repetitive and often monotonous task of data collection accompanied by accuracy and objectivity as much as possible. another and equally important point for the anesthesiologists is to remove some of the pencil-and-paper burden, reduce the possibilities of human errors in reading instruments and note-taking and the rapid retrieval of monitored and stored data for the purp ...19751233480
a code of ethics for a community mental health program.the orange county department of mental health developed a code of ethics to give its variety of employees a single set of standards for patient care and professional behavior in a community mental health program. the need for the code grew from problems of role definition and interdisciplinary collaboration that repeatedly arose during the program's development. general principles for the code were extracted from various professional codes, from issues arising in the day-to-day workings of the p ...19761245312
epidemiology of influenza in the elderly: evidence of virus recycling.during the hong kong influenza epidemic of 1968-1969 the attack rate among persons born prior to 1890 was about one-third the rate among persons born after 1899. during an asian influenza epidemic in the same community two years earlier there was no apparent age effect. most persons born before 1890 had detectable pre-epidemic antibody against a/hong kong/68 whereas most persons born after 1899 had no detectable pre-epidemic antibody. the lower attack rate in the older age group is consistent wi ...19761251831
hiv prevention and the two faces of partner notification.in the cases of medical patients with sexually transmitted diseases (particularly those with the human immunodeficiency virus), two distinct approaches exist to notifying sexual and/or needle-sharing partners of possible risk. each approach has its own history (including unique practical problems of implementation) and provokes its own ethical dilemmas. the first approach--the moral "duty to warn"--arose out of clinical situations in which a physician knew the identity of a person deemed to be a ...19921304728
seroepidemiology of viral infections among intravenous drug users in northern california.intravenous drug users are frequently exposed to parenterally transmitted viral infections, and these infections can spread to the general population through sexual activity. we investigated the prevalence of serologic markers for human immunodeficiency virus type 1 (hiv-1), human t-cell lymphotropic virus type i/ii (htlv-i/ii), hepatitis b virus (hbv), and hepatitis c virus (hcv) in intravenous drug users and their sexual contacts. of 585 drug users from northern california tested for these ser ...19921310362
arboviral disease--united states, 1991.during 1991, state and local health departments reported 122 cases of human arboviral encephalitis to cdc. more than half (69) of the cases resulted from outbreaks of st. louis encephalitis (sle) in arkansas and texas. in addition, an epizootic of eastern equine encephalitis (eee) extending from the atlantic and gulf coasts into the upper midwest caused sporadic human cases and a substantial loss of livestock. this report summarizes the reported cases of arboviral encephalitis in the united stat ...19921321947
clinical, epidemiologic, and virologic studies in four clusters of the chronic fatigue syndrome.the purpose of this study is to provide a case definition of chronic fatigue syndrome in an outbreak occurring in the nevada-california region to evaluate candidate etiologic agents and observe the natural history of the illness.19921323246
comparison of indirect immunofluorescence and membrane fluorescence assays for the differentiation of antibodies to human immunodeficiency virus types 1 and 2.serum samples from 20 human immunodeficiency virus type 1 (hiv-1)- and 30 hiv-2-infected and 7 dually infected individuals were reacted by using the indirect immunofluorescence assay (ifa) and membrane fluorescence assay in order to determine whether these methods were useful for typing hiv-1 and hiv-2 antibodies. although 41 of 50 (82%) of the hiv-1- and hiv-2-positive specimens cross-reacted to some extent with the heterologous antigen in the ifa, the antigen with the higher titer correlated c ...19921328285
serum epoxide hydrolase (preneoplastic antigen) in human and experimental liver injury.reports of an increase in a serum epoxide hydrolase (seh), immunochemically related to microsomal eh in humans and rats with hepatocellular carcinoma (hcc), suggested its use as a serum marker for this disease. we have now measured seh levels (as either immunochemically determined content or enzyme activity) in a number of human and experimental models of liver disease. seh was elevated above the normal range in at least 50% of individuals with hcc, including: 3 of 6 northern californians; 4 of ...19921339049
forecasts of the costs of medical care for persons with hiv: 1992-1995.this study concludes that the cumulative (national) cost of treating all persons with the human immunodeficiency virus (hiv) rose considerably over the past year and will continue to rise over the next several years. it is forecast that the cumulative cost of treating all persons with hiv will increase 48% from 1992 to 1995 (from $10.3 billion to $15.2 billion). it is estimated that the average yearly cost of treating a person with aids is $38,300 and of treating an infected person without aids ...19921356925
seroepidemiology of california and bunyamwera serogroup bunyavirus infections in humans in california.several human populations in california were surveyed cross-sectionally and longitudinally for neutralizing antibodies to selected arthropod-borne bunyaviruses in the california and bunyamwera serogroups. overall, the prevalence of antibodies to california serogroup viruses was 6.4% in 702 individuals sampled during 1963-1988. comparative antibody titers in individual sera indicated that 4.1% and 1.6% of these infections were caused by viruses similar or identical to jamestown canyon and califor ...19921357960
molecular cloning and sequence analysis of an isolate of hepatitis c virus from southern california, u.s.a.we obtained a cdna clone representing a partial rna sequence of a human hepatitis c virus (hcv) isolate from southern california. rna was extracted from the liver tissue of a patient with post-transfusion hepatitis, and used for cdna synthesis and polymerase chain reaction (pcr) amplification using oligonucleotide primers specific for the prototype hcv rna. the cdna clone obtained contains 585 base pairs of hcv sequences and represents the region encoding the putative nonstructural protein ns3 o ...19921364214
the risk management of infections.unfortunately, risk management, that is avoiding lawsuits, is a retro-active pastime instead of being pro-active. what this means is that we often take action only after a problem has manifested itself, rather than identifying potential problems and correcting them. this is, however, only human nature and occurs in most other walks of life. in dental malpractice, what appears to have been happening during the past few years in california is that plaintiff's lawyers have identified a problem and ...19921389588
risk for aids in multiethnic neighborhoods in san francisco, california. the population-based amen study.to examine the actual and potential spread of human immunodeficiency virus (hiv) from an acquired immunodeficiency syndrome (aids) epicenter to surrounding neighborhoods, we studied the prevalence of the viral infection and aids risk behaviors from 1988 to 1989 in a representative sample of unmarried whites, african americans, and hispanics living in san francisco. we surveyed 1,770 single men and women aged 20 to 44 years (a 64% response rate) in a random household sample drawn from 3 neighborh ...19921413740
health care use by human immunodeficiency virus-infected students at a california student health service.we report characteristics of 16 college students with human immunodeficiency virus (hiv) infection but without the acquired immunodeficiency syndrome who received care at a student health center at a major university in california. sociodemographic and clinical data and medical expenditures were obtained retrospectively from medical charts and computerized billing records. all 16 students were men who had sex with men, and 3 had also used intravenous drugs. dermatologic conditions, upper respira ...19921413741
high-risk sexual behavior and condom use among gay and bisexual african-american men.little is known about the human immunodeficiency virus (hiv) high-risk sexual practices of gay and bisexual african-american men. these data are needed so that better interventions can be developed and implemented in this population.19921443298
screening women of childbearing age for human immunodeficiency virus. a cost-benefit analysis.in light of the increasing problem of perinatal human immunodeficiency virus (hiv) transmission, the issue of screening women for hiv is receiving considerable attention. we analyzed the costs and benefits of screening women of childbearing age for hiv. the analysis was based on a dynamic model of the hiv epidemic that incorporated disease transmission and progression, behavioral changes, and effects of screening and counseling. we found that the primary benefit of screening programs targeted to ...19921444682
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