| dna fingerprinting in the epidemiology of african serogroup a neisseria meningitidis. | the restriction endonuclease (re) technique was used to compare 172 meningococcal group a strains collected between 1969 and 1990, mainly from countries of the so-called african meningitis belt, the gambia and ethiopia. the 64 strains from various african countries (niger, chad, burkina faso, cameroon, morocco, djibouti) were distributed within 3 main restriction enzyme patterns (reps); the 77 gambian strains fell into 5 reps and the 24 ethiopian strains into 2 such patterns. several of the main ... | 1992 | 1324522 |
| nasopharyngeal carriage of neisseria meningitidis in general population and meningococcal disease. | nasopharyngeal carriage of neisseria meningitidis was determined in the normal healthy population in delhi at monthly intervals for a period of 2 years from january, 1986 to december, 1987. of a total of 6513 individuals screened only 107 (1.64 per cent) were found to carry neisseria meningitidis serogroup a. there was no age and sex difference in carriage. during the same period, data of laboratory confirmed cases of meningitis due to n. meningitidis serogroup a was obtained from 6 hospitals of ... | 1990 | 2129123 |
| sulphadiazine resistant group 'a' meningococci isolated during the meningitis outbreak in delhi (1985). | | 1987 | 3119473 |
| nasopharyngeal carriers among contact of patients of neisseria meningitidis infection in delhi. | | 1987 | 3443479 |
| meningococcal disease--outbreak in delhi. | meningococcal disease occurs both endemically and epidemically across the world. in india also meningococcal disease occurs sporadically with epidemics occurring at regular intervals. epidemics of meningococcal disease have occurred in delhi in the year 1935, then in the year 1966 which lasted for a year and again in 1985-86. the last epidemic took a great toll with case fatality rate nearly 13%. this year also there has been an outbreak of meningococcal disease with nearly 400 cases and case fa ... | 2005 | 15995271 |
| meningococcal disease: history, epidemiology, pathogenesis, clinical manifestations, diagnosis, antimicrobial susceptibility and prevention. | meningoccocal disease has repeatedly caused outbreaks worldwide. there has been sudden surge of cases of meningococcemia and meningococcal meningitis in early 2005 in delhi, india and neighboring states of uttar pradesh and haryana. as of june 17, 2005, 429 probable cases of meningococcal disease have been reported in delhi out of which 128 cases have revealed microbiological evidence of neisseria meningitidis. it is possible that the number of cases was in excess of the numbers notified. during ... | 2006 | 16505549 |
| meningococcaemia: experience at a tertiary care hospital in east delhi. | | 2006 | 17185854 |
| ciprofloxacin-resistant neisseria meningitidis, delhi, india. | decreased susceptibility of neisseria meningitidis isolates to ciprofloxacin emerged from an outbreak in delhi, india. results of antimicrobial susceptibility testing of the meningococcal isolates to ciprofloxacin and further sequencing of dna gyrase a quinolone-resistance-determining region confirmed the emergence of ciprofloxacin resistance in the outbreak. | 2007 | 18258023 |
| the rise and fall of epidemic neisseria meningitidis from a tertiary care hospital in delhi, january 2005-june 2007. | meningococcal meningitis is endemic in india. there has been a sudden surge of cases of meningococcal meningitis in 2005 in delhi. present study was undertaken to find out changing trends in incidence of this disease from a tertiary care hospital in new delhi over a period of two and half years. all samples from suspected cases of meningococcal meningitis were subjected to gram staining, culture and latex agglutination test for detection of neisseria meningitidis (n.meningitidis). antimicrobial ... | 2008 | 18820189 |
| outbreak of meningococcal disease in and around new delhi, india, 2005-2006: a report from a tertiary care hospital. | the first of several cases of meningococcal meningitis was reported in april 2005, in new delhi, india. subsequent to this the government declared an outbreak, which persisted for two periods, from april-july 2005 and january-march 2006. the national institute of communicable diseases (nicd) recommended using who criteria for diagnosis of disease. during the outbreak 380 clinically suspected cases were investigated. of 55 cases diagnosed as confirmed/probable the mortality rate was 14.6%. mening ... | 2009 | 18840317 |
| clinical profile of group a meningococcal outbreak in delhi. | we present a retrospective analysis of clinical profile of 100 children admitted to a government hospital at delhi between april 2005 and december 2006 with group a meningococcal infection. maximum children presented in late winter and spring. younger children were less affected (5% children < 1 year). fever (86%), vomiting (64%) and rash (63%) were the most common presenting symptoms. all children presented within 5 days of onset of symptoms and 52% within 24 hours. 67 % children had meningococ ... | 2009 | 19179744 |
| incidence and outcome of arthritis in meningococcal disease. | meningococcal outbreaks are a major health concern in delhi and adjoining regions. besides acute pyogenic meningitis, meningococcal disease can also manifest as vasculitis, dermatitis and arthritis. to study the frequency, characteristics and long-term outcome of joint involvement in may 2005 meningococcal outbreak in new delhi, 24 patients with proven meningococcal disease admitted to the hospital from may, 2005 through august, 2005 were studied for occurrence and outcome of joint involvement, ... | 2009 | 19810382 |
| meningococcal vaccine: a new vaccine to combat meningococcal disease in india. | meningococcal meningitis is caused by neisseria meningitidis, a gram-negative, aerobic, encapsulated diplococcus. meningococci are divided into numerous serogroups based on the composition of their capsular polysaccharide (ps) antigens. at least 13 serogroups have been described: a, b, c, d, 29e, h, i, k, l, w-135, x, y and z. out of these 13, six (a, b, c, w135, x and y) can cause epidemics. the incubation period averages 3-4 d (range 1-10 d), which is the period of communicability. bacteria ca ... | 2012 | 22906940 |
| antigen sequence typing of outer membrane protein (feta) gene of neisseria meningitidis serogroup a from delhi & adjoining areas. | meningitis caused by neisseria meningitidis is a fatal disease. meningococcal meningitis is an endemic disease in delhi and irregular pattern of outbreaks has been reported in india. all these outbreaks were associated with serogroup a. detailed molecular characterization of n. meningitidis is required for the management of this fatal disease. in this study, we characterized antigenic diversity of surface exposed outer membrane protein (omp) feta antigen of n. meningitidis serogroup a isolates o ... | 2014 | 25758575 |
| ciprofloxacin-resistant neisseria meningitidis in canada: likely imported strains. | the prevalence of ciprofloxacin-resistant neisseria meningitidis in canada was studied by testing 346 isolates received at the national microbiology laboratory during the calendar years 2013 to 2015. of the 277 individual invasive and 69 noninvasive isolates tested, only 2 serogroup c (menc) isolates were found to be resistant to ciprofloxacin. both menc were typed as sequence type (st)-4821, a unique clone found mainly in china, thus suggesting both isolates might be from travel-related or impo ... | 2017 | 28140652 |
| an overview of meningococcal disease in india: knowledge gaps and potential solutions. | the global meningococcal initiative (gmi) consists of an international group of scientists and clinicians, with expertise in meningococcal immunology, epidemiology, public health and vaccinology that aims to prevent meningococcal disease worldwide through education, research, cooperation and vaccination. in india, there is no national policy on routine meningococcal vaccination to control the disease. the gmi convened a meeting in india, with local medical leaders and public policy personnel, to ... | 2013 | 23588082 |