| human streptococcus suis outbreak, sichuan, china. | from mid-july to the end of august 2005, a total of 215 cases of human streptococcus suis infections, 66 of which were laboratory confirmed, were reported in sichuan, china. all infections occurred in backyard farmers who were directly exposed to infection during the slaughtering process of pigs that had died of unknown causes or been killed for food because they were ill. sixty-one (28%) of the farmers had streptococcal toxic shock syndrome; 38 (62%) of them died. the other illnesses reported w ... | 2006 | 16707046 |
| [an outbreak of human streptococcus suis serotype 2 infections presenting with toxic shock syndrome in sichuan, china]. | in mid-july 2005, five patients presented with septic shock to a hospital in ziyang city in sichuan, china, to identify the etiology of the unknown reason disease, an epidemiological, clinical, and laboratory study were conducted. | 2006 | 16792880 |
| streptococcus suis sequence type 7 outbreak, sichuan, china. | an outbreak of streptococcus suis serotype 2 emerged in the summer of 2005 in sichuan province, and sporadic infections occurred in 4 additional provinces of china. in total, 99 s. suis strains were isolated and analyzed in this study: 88 isolates from human patients and 11 from diseased pigs. we defined 98 of 99 isolates as pulse type i by using pulsed-field gel electrophoresis analysis of smai-digested chromosomal dna. furthermore, multilocus sequence typing classified 97 of 98 members of the ... | 2006 | 16965698 |
| [isolation and identification of streptococcus suis serotype 2 from sick-pig samples of sichuan province]. | streptococcus suis serotype 2 (ss2) is a major pathogen frequently associated with infections in pigs. there are presently 35 serotypes of s.suis (serotype 1 to 34 and serotype 1/2) recognized on the basis of capsular antigens. few people were reported to infect with ss2 in the past years. however, an accidental case happened in sichuan province of china in 2005. some people got ill and died, and all of them were closely contacted with sick pigs. based on clinical features and epidemiologic data ... | 2006 | 17037069 |
| [mlst typing of streptococcus suis isolated from clinical patients in guangdong province in 2005]. | objective: intensive surveillance of human s.suis infection was carried out in july and august of 2005 in guangdong province, which coincided with the sichuan outbreak. five isolated cases of human infections were identified during this period, from which 5 s. suis serotype 2 isolates were recovered. mlst analysis showed that these 5 isolates shared identical sequences of 6 mlst housekeeping genes except for one point mutation found within the thra gene fragment, a neutral mutation (tta to ttg) ... | 2008 | 18753081 |
| the role of toll-like receptors in the pathogenesis of streptococcus suis. | streptococcus suis is an important agent of swine and human meningitis. sequence type (st) 7 emerged in china and was responsible for the human epidemic caused by s. suis in 2005. the virulence of s. suis st7 is greater than the wild type pathogenic s. suis, st1; however, the mechanisms for this increased pathogenicity are unknown. the aim of this study was to determine the role of different toll-like receptors (tlrs) involved in regulating the host response to the s. suis infection and to specu ... | 2011 | 22055206 |
| streptococcal toxic shock syndrome caused by streptococcus suis serotype 2. | streptococcus suis serotype 2 (s. suis 2, ss2) is a major zoonotic pathogen that causes only sporadic cases of meningitis and sepsis in humans. most if not all cases of streptococcal toxic shock syndrome (stss) that have been well-documented to date were associated with the non-ss2 group a streptococcus (gas). however, a recent large-scale outbreak of ss2 in sichuan province, china, appeared to be caused by more invasive deep-tissue infection with stss, characterized by acute high fever, vascula ... | 2006 | 16584289 |
| [matched case-control study for risk factors of human streptococcus suis infection in sichuan province, china]. | to study the potential risk factors of human infecting with streptococcus suis. | 2005 | 16471206 |
| isolation and characterization of 89k pathogenicity island-positive st-7 strains of streptococcus suis serotype 2 from healthy pigs, northeast china. | streptococcus suis is a swine pathogen which can also cause severe infection, such as meningitis, and streptococcal-like toxic shock syndrome (stss), in humans. in china, most of the s. suis infections in humans were reported in the southern areas with warm and humid climates, but little attention had been paid to the northern areas. data presented here showed that the virulent serotypes 1, 2, 7, and 9 of s. suis could be steadily isolated from the healthy pigs in the pig farms in all the three ... | 2012 | 22701353 |
| streptococcus suis outbreak investigation using multiple-locus variable tandem repeat number analysis. | two outbreaks of streptococcus suis st7 occurred in humans in 1998 and 2005 in china. pfge of chromosome restriction fragments found all st7 isolates to be indistinguishable. due to the genetic homogeneity of st7 isolates, development of a rapid sub-typing method with high discriminatory power for st7 isolates is required. in this study, a novel method, mlva, was developed to type s. suis serotype 2 strains. further, this method was used to analyze outbreak-associated st7 strains in china. a tot ... | 2010 | 20618684 |
| recurrence of human streptococcus suis infections in 2007: three cases of meningitis and implications that heterogeneous s. suis 2 circulates in china. | emergence of fatal streptococcus suis serotype 2 (s. suis 2, ss2) in china, 2005, has greatly challenged the public health, raising serious concerns about its global circulation. whole genome sequencing of the representative strains has identified a potential pathogenicity island (pai), named 89k. here, we reported the recurrence of human s. suis meningitis cases (two in shenzhen city and one in sichuan province) in china, in 2007. multiple lines of evidence supported that these human cases are ... | 2009 | 19538458 |
| streptococcus suis infections in humans: the chinese experience and the situation in north america. | infections caused by streptococcus suis are considered a global problem in the swine industry. in this animal species, s. suis is associated with septicemia, meningitis, endocarditis, arthritis and, occasionally, other infections. moreover, it is an agent of zoonosis that afflicts people in close contact with infected pigs or pork-derived products. although sporadic cases of s. suis infection in humans have been reported, a large outbreak due to s. suis serotype 2 emerged in the summer of 2005 i ... | 2007 | 17692141 |
| adhesion activity of glyceraldehyde-3-phosphate dehydrogenase in a chinese streptococcus suis type 2 strain. | a total of 36 streptococcal strains, including seven s. equi ssp.zooepidemicus, two s. suis type 1 (ss1), 24 ss2, two ss9, and one ss7, were tested for glyceraldehyde-3-phosphate dehydrogenase gene (gapdh). except from non-virulent ss2 strain t1 5, all strains harboured gapdh. the gapdh of chinese sichuan ss2 isolate zy05719 and jiangsu ss2 isolate ha9801 were sequenced and then compared with published sequences in the genbank. the comparison revealed a 99.9 % and 99.8 % similarity of zy05719 an ... | 2007 | 17555040 |
| an outbreak of streptococcus suis in chengdu, china. | | 2007 | 17504369 |