Publications

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[a study on efficacy of rabies vaccine prepared by primary hamster kidney cells in guangxi].to study the efficacy of post-exposure use of concentrated rabies vaccine prepared by primary hamster kidney cells during the past 16 years (1980-1995) in the guangxi zhuang autonomous region and the role of ambulant care for the victims injured by dog-bite.199810322757
[molecular epidemiological characterization of rabies virus isolated from guangxi].to analyze the genotype of rabies virus isolated from different areas in guangxi at different time.200111986719
molecular epidemiology of rabies in guangxi province, south of china.surveillance data for rabies in guangxi province in china showed that human rabies cases have gradually increased since 1996.200717588806
[survey and anslysis of infection rate of dog rabies in the regions with high incidence of human rabies].to investigate the situation of dog rabies and analyze it's relationship with human rabies.200819031690
[characterization of rabies virus phosphoprotein in high prevalence provinces of china].characterization of rabies virus phosphoprotein through analyzation of genetic variations about rabies virus phosphoproteins in high-incidence regions in china.200819031691
[the primary application of direct rapid immunohistochemical test to rabies diagnosis in china].evaluation of the direct rapid immumohistochemical test (drit) for laboratory surveillance of rabies.200819031692
[viral surveillance on rabies in hunan province, in 2006].to understand the source and distribution of rabies virus (rv) in hunan province with viral surveillance in order to provide scientific measures for prevention and control on rabies.200819173884
molecular characterization of the complete genome of a street rabies virus isolated in china.in this study, the complete genomic sequence of a rabies virus isolate hn10, recovered from brain tissue of a rabid patient in china, was determined. this is the first chinese street isolate that has been fully characterized. the overall organization of this virus is typical of that observed for all other rabies viruses. alignments of amino acid sequences of the phosphoprotein, glycoprotein and large protein of hn10 with those of other rabies viruses were used to examine the extent of conservati ...200919463716
molecular epidemiology of rabies in southern people's republic of china.in recent years, the number of human rabies cases in the people's republic of china has increased during severe epidemics in 3 southern provinces (guizhou, guangxi, and hunan). to analyze the causes of the high incidence of human rabies in this region, during 2005-2007, we collected 2,887 brain specimens from apparently healthy domestic dogs used for meat consumption in restaurants, 4 specimens from suspected rabid dogs, and 3 from humans with rabies in the 3 provinces. partial nucleoprotein gen ...200919751579
[analysis of human rabies high-occurrence factors in guangxi from 2004 to 2008].analysis the epidemiological characteristics on rabies cases occurred in guangxi from 2004 to 2008 and summarize the result of healthy-dog infection rabies virus investigation from 2006 to 2008. exploring the high-occurrence and correlated factors on rabies in guangxi.201021110421
modeling the transmission dynamics and control of rabies in china.human rabies was first recorded in ancient china in about 556 bc and is still one of the major public-health problems in china. from 1950 to 2015, 130,494 human rabies cases were reported in mainland china with an average of 1977 cases per year. it is estimated that 95% of these human rabies cases are due to dog bites. the purpose of this article is to provide a review about the models, results, and simulations that we have obtained recently on studying the transmission of rabies in china. we fi ...201728188732
modeling the geographic spread of rabies in china.in order to investigate how the movement of dogs affects the geographically inter-provincial spread of rabies in mainland china, we propose a multi-patch model to describe the transmission dynamics of rabies between dogs and humans, in which each province is regarded as a patch. in each patch the submodel consists of susceptible, exposed, infectious, and vaccinated subpopulations of both dogs and humans and describes the spread of rabies among dogs and from infectious dogs to humans. the existen ...201526020234
re-emergence of rabies in the guangxi province of southern china.human rabies cases in the guangxi province of china decreased from 839 in 1982 to 24 in 1995, but subsequently underwent a sharp increase, and has since maintained a high level.201425275567
characterization of the biological properties and complete genome sequence analysis of a cattle-derived rabies virus isolate from the guangxi province of southern china.in this study, a street rabies virus isolate, gxhxn, was obtained from the brain of one rabid cattle in guangxi province of southern china. to characterize the biological properties of gxhxn, we first evaluated its pathogenicity using 4-week-old adult mice. gxhxn was highly pathogenic with a short incubation period and course of disease. its ld50 of 10(-6.86)/ml is significantly higher than the ld50 of 10(-5.19)/ml of gxn119, a dog-derived rabies virus isolate. it also displayed a higher neurotr ...201425142164
lyssavirus surveillance in bats of southern china's guangxi province.although rabies virus is widely distributed in the world, and has been the subject of extensive investigations with the objective of its ultimate prevention, control, and management, there is much less knowledge of the characteristics, distribution, and infectivity of other lyssaviruses. since bats are known animal vectors for all but one of the known lyssavirus genotypes, we have performed an extensive survey of bats in the guangxi province to provide information on lyssavirus distribution in s ...201323197137
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