| prevalence of plasmid-mediated quinolone-resistance determinants in shigella flexneri isolates from anhui province, china. | quinolones are used extensively to treat shigella flexneri infection, and plasmid-mediated quinolone resistance (pmqr) determinants were recently reported. a total of 26 s. flexneri isolates collected from anhui province, china, in 2005 were screened for pmqr determinants, bla gene, gyra and parc genes, by pcr and sequencing. pmqr determinants were present in 53.8% (14 of 26) of isolates and qnra(1), qnrs(1), qnrs(2), aac(6')-ib-cr and qepa were present in 30.8, 11.5, 3.8, 19.2 and 11.5% of thos ... | 2010 | 20203702 |
| genomic portrait of the evolution and epidemic spread of a recently emerged multidrug-resistant shigella flexneri clone in china. | shigella flexneri is the major cause of shigellosis in developing countries. a new s. flexneri serotype, xv, appeared in 2000 and replaced serotype 2a as the most prevalent serotype in china. serotype xv is a variant of serotype x, with phosphoethanolamine modification of its o antigen mediated by a plasmid that contained the opt gene. serotype xv isolates belong to sequence type 91 (st91). in this study, whole-genome sequencing of 59 s. flexneri isolates of 14 serotypes (serotypes 1 to 4, y, yv ... | 2014 | 24452172 |