| [treatment of hepatitis c: supporting mobilization so that persons infected with hepatitis c virus have access to treatment]. | | 2010 | 21744638 |
| epidemic of group a streptococcus m/emm59 causing invasive disease in canada. | the incidence of invasive group a streptococcus (gas) disease can vary over time and geographic region, possibly reflecting the population's susceptibility to particular strains but also variation in the predominant m/emm types. canadian surveillance documented an epidemic of an uncommon m/emm59 type from 2006 to 2009. | 2010 | 21034198 |
| hepatitis c virus incidence among young street-involved idus in relation to injection experience. | young injection drug users (idus) are at very high risk of hepatitis c virus (hcv) infection. using a time scale starting at first injection, we studied the period of hcv susceptibility after initiation into drug injection among street-involved idus. | 2009 | 19251382 |
| access to sterile injecting equipment is more important than awareness of hcv status for injection risk behaviors among drug users. | awareness of hepatitis c virus (hcv) infection status is expected to influence risk behaviors. in 2004-2005, injection drug users (idus) recruited from syringe exchange programs (seps) and methadone clinics in montreal, canada, were interviewed on drug use behaviors (past 6 months) and hcv testing. subjects (n = 230) were classified as low/intermediate risk (20.4% borrowed drug preparation equipment only) and high risk (19.6% borrowed syringes), and 54.5% reported being hcv positive. logistic re ... | 2009 | 19242863 |
| pediatric injuries from needles discarded in the community: epidemiology and risk of seroconversion. | although anxiety exists concerning the perceived risk of transmission of bloodborne viruses after community-acquired needlestick injuries, seroconversion seems to be rare. the objectives of this study were to describe the epidemiology of pediatric community-acquired needlestick injuries and to estimate the risk of seroconversion for hiv, hepatitis b virus, and hepatitis c virus in these events. | 2008 | 18676535 |
| mode of transmission, rather than the hepatitis c virus, as a major determinant of poor interpersonal relationships in patients with chronic hepatitis c. | recent studies have demonstrated that patients with the hepatitis c virus (hcv) have significant neurocognitive impairment. | 2007 | 18080053 |
| hepatitis c meanings and preventive strategies among street-involved young injection drug users in montréal. | to examine what hepatitis c virus (hcv) infection means to street-involved young idus (syidus) and how this impacts on their health behaviours, based on social contexts in which they live. | 2007 | 17854728 |
| prevalence of hiv and hepatitis c virus infections among inmates of quebec provincial prisons. | to determine the prevalence of hiv and hepatitis c virus (hcv) infections and examine risk factors for these infections among inmates in quebec provincial prisons. | 2007 | 17664448 |
| prevalence and associated factors of hepatitis c infection (hcv) in a multi-site canadian population of illicit opioid and other drug users (opican). | hepatitis c virus (hcv) infection is highly prevalent in illicit drug user populations, with three in four new hcv infections related to this risk behaviour and a growing hcv disease burden in canada. using data from a multi-site cohort study of illicit opioid users in five canadian cities (opican), this paper explores the prevalence and predictors of hcv status in this high-risk population. | 2007 | 17441537 |
| use of sequence analysis of the ns5b region for routine genotyping of hepatitis c virus with reference to c/e1 and 5' untranslated region sequences. | nucleotide sequence analysis of the ns5b region was performed to identify genotypes of 8,479 hepatitis c virus (hcv) rna-positive patient samples collected in the canadian province of quebec. genotypes could be determined for 97.3% of patients. genotypes 1 to 6 were found in 59.4, 9.0, 25.7, 3.6, 0.6, and 1.8% of patients, respectively. two isolates did not classify within the six genotypes. the subtype 1 distribution was 76.7% 1a, 22.6% 1b, and 0.7% others, while the subtype 2 distribution was ... | 2007 | 17287328 |
| crack across canada: comparing crack users and crack non-users in a canadian multi-city cohort of illicit opioid users. | to examine possible differences between crack users and crack non-users across canada. | 2006 | 17156175 |
| elderly patients are at greater risk of cytopenia during antiviral therapy for hepatitis c. | the results of antiviral therapy for hepatitis c virus (hcv) have improved recently with the use of pegylated interferon (peg-ifn)/ribavirin (rbv) combination therapy. at this point, most patients with chronic hcv remain untreated. thus, it is anticipated that therapy will be more appealing and prescribed more broadly than in the past, including in patients considered marginal. | 2006 | 17001400 |
| predictors of antiviral therapy in a post-transfusion cohort of hepatitis c patients. | in the past, antiviral therapy has been given to 15% to 30% of patients infected with hepatitis c virus (hcv). the efficacy of therapy has recently improved with the addition of ribavirin and pegylated interferon. the aim of the present study was to identify the clinical, socioeconomic and health-system predictors of antiviral treatment for hcv. | 2006 | 16482237 |
| food insecurity in hiv-hepatitis c virus co-infected individuals in canada: the importance of co-morbidities. | while research has begun addressing food insecurity (fi) in hiv-positive populations, knowledge regarding fi among individuals living with hiv-hepatitis c virus (hcv) co-infection is limited. this exploratory study examines sociodemographic, socioeconomic, behavioral, and clinical factors associated with fi in a cohort of hiv-hcv co-infected individuals in canada. we analyzed longitudinal data from the food security and hiv-hcv co-infection study of the canadian co-infection cohort collected bet ... | 2017 | 26912217 |
| risks associated with transfusion of cellular blood components in canada. | we provide a comprehensive review of risks associated with allogeneic red blood cell and platelet transfusions in canada. the review focuses on clinically symptomatic noninfectious transfusion risks (acute and delayed hemolytic, febrile nonhemolytic [fnhtr], allergic, volume overload, transfusion-related acute lung injury, graft-versus-host disease, and posttransfusion purpura) and the risk of clinically significant disease from transfusion-transmitted infections. data sources include informatio ... | 2003 | 12733105 |
| an epidemiologic study of hepatocellular carcinoma in canada. | to provide information on poorly described canadian hepatocellular cancer epidemiology, we analyzed incident cases abstracted from the canadian cancer registration database (1969-1997) and canadian annual death data (1969-1998). age, sex, geographic distribution, and secular trends were described. projection models were developed for the next decade. | 2002 | 12448868 |
| risk factors for hepatitis c virus infection among street youths. | the relative contributions to risk of hepatitis c virus (hcv) infection resulting from unsafe sexual behaviours and exposures to blood (e.g., tattooing, body piercing and injection drug use) among youths at risk are not well known. we interviewed street youths about risk factors for hcv infection and documented their hcv antibody status. | 2001 | 11563207 |
| targeted hepatitis c lookback: quebec, canada. | since march 1990, all blood donations in canada are screened for antibodies to hepatitis c virus (hcv). because hcv may cause chronic asymptomatic hepatitis, in february 1995, the canadian red cross began targeted hcv lookback studies. | 1999 | 10037131 |
| identification of numerous hepatitis c virus genotypes in montreal, canada. | hepatitis c virus genotypes were determined for 358 viremic individuals in montreal, canada, by restriction endonuclease analysis of pcr products and phylogenetic analysis of core gene sequences. types 1, 2, and 3 occurred in 62.8, 14.2, and 13.7%, respectively; types 4 and 5 were found in 3.9 and 4.5%, respectively; and genotypes 6a and 7c and a novel genotype each occurred in 0.3%. types 4, 6, and 7 and the novel genotype were mostly from persons who had immigrated to canada. | 1996 | 8897188 |
| use of the 5' noncoding region for genotyping hepatitis c virus. | | 1994 | 7906294 |
| hepatitis c virus genotypes in patients and blood donors--quebec. | | 1995 | 7670431 |
| the 3rd canadian symposium on hepatitis c virus: expanding care in the interferon-free era. | hepatitis c virus (hcv) currently infects approximately 250,000 individuals in canada and causes more years of life lost than any other infectious disease in the country. in august 2011, new therapies were approved by health canada that have achieved higher response rates among those treated, but are poorly tolerated. by 2014⁄2015, short-course, well-tolerated treatments with cure rates >95% will be available. however, treatment uptake is poor due to structural, financial, geographical, cultural ... | 2014 | 25314353 |
| lack of evidence of sexual transmission of hepatitis c virus in a prospective cohort study of men who have sex with men. | we studied the prevalence and incidence of hepatitis c virus (hcv) infection in the ongoing omega cohort study of men who have sex with men (msm). | 2005 | 15727984 |
| use of a novel washing method combining multiple density gradients and trypsin for removing human immunodeficiency virus-1 and hepatitis c virus from semen. | to determine the effectiveness of a novel treatment designed to remove human immunodeficiency virus (hiv) -1 and hepatitis c virus (hcv) from spiked semen and to evaluate sperm motility and viability after treatment. | 2005 | 16213856 |
| the second canadian symposium on hepatitis c virus: a call to action. | in canada, hepatitis c virus (hcv) infection results in considerable morbidity, mortality and health-related costs. within the next three to 10 years, it is expected that tolerable, short-duration (12 to 24 weeks) therapies capable of curing >90% of those who undergo treatment will be approved. given that most of those already infected are aging and at risk for progressive liver disease, building research-based interdisciplinary prevention, care and treatment capacity is an urgent priority. in a ... | 2013 | 24199209 |
| a population-based study of chronic hepatitis c in immigrants and non-immigrants in quebec, canada. | immigrants originating from intermediate and high hcv prevalence countries may be at increased risk of exposure to hepatitis c infection (hcv) in their countries of origin, however they are not routinely screened after arrival in most low hcv prevalence host countries. we aimed to describe the epidemiology of hcv in immigrants compared to the canadian born population. | 2017 | 28193199 |
| using the evaluation process as a lever for improving health and healthcare accessibility: the case of hcv services organization in quebec. | the evaluation process can be a lever to improve pathways of access to healthcare. the objective of this article is to show how an evaluation strategy can both contribute to knowledge development and have direct impacts on health services provision. we use the case of hepatitis c (hcv) services organization to illustrate the use and the value of this evaluative approach. | 2016 | 26851873 |
| diagnostic accuracy of algorithms to identify hepatitis c status, aids status, alcohol consumption and illicit drug use among patients living with hiv in an administrative healthcare database. | this study aims to develop and evaluate diagnostic algorithms for aids, hepatitis c status, alcohol abuse and illicit drug use in the administrative healthcare database of the province of quebec, canada (régie de l'assurance-maladie du québec (ramq)). | 2015 | 26114918 |