Publications

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colonization and establishment of pomphorhynchus laevis (acanthocephala) in an isolated english river.the successful colonization, establishment and spread of pomphorhynchus laevis in a small, isolated, devon river 128 km from the parasite's nearest focus in dorset was followed over 11 years from 1985. the parasite was first detected in anguilla anguilla and platichthys flesus in 1988: by 1995 it had attained prevalence levels of 22.6% in a. anguilla and 43.6% in p. flesus and also occurred in 100% salmo trutta, 50% cottus gobio and noemacheilus barbatulus. as judged by prevalence, abundance, pr ...19968991914
the extent of oestrogenic contamination in the uk estuarine and marine environments--further surveys of flounder.in 1996, the centre for environment, fisheries and aquaculture science (cefas) initiated a project to establish whether oestrogenic materials are present in uk estuarine and marine waters at biologically significant concentrations, and to investigate some of the possible effects which these may have in flounder (platichthys flesus). early results are published elsewhere; this paper describes the results of a second wider survey of vitellogenin and reproductive abnormalities in uk flounder. vitel ...199910492895
the detection of biomarkers of genotoxin exposure in the european flounder (platichthys flesus) collected from the river tyne estuary.the tyne estuary (north east england) is known to contain elevated levels of polycyclic aromatic hydrocarbons (pah), compared with other less industrialised english waterways. previous studies suggest that such contamination is responsible for the toxicity detected in invertebrate bioassays conducted on water and sediment samples collected from the tyne. here we present data from a biomonitoring study using hepatic dna adducts (32p-postlabelling assay) and bile metabolites (synchronous fluoresce ...199910613191
incorporation of organic tritium (3h) by marine organisms and sediment in the severn estuary/bristol channel (uk).discharges of tritium (3h) into the severn estuary/bristol channel (uk) arise from the authorized release of wastes from nuclear power plants at hinkley point and berkley/oldbury and from the nycomed-amersham radiochemical plant, via the sewer system, at cardiff. the wastes from the nuclear power plants probably consist almost entirely of 3h2o, whereas those from the radiochemical plant also include uncharacterized 3h labelled organic compounds. the total 3h concentrations in demersal fish and o ...200111693639
hepatic ethoxyresorufin o-deethylase (erod) activity in flounder (platichthys flesus) from contaminant impacted estuaries of the united kingdom: continued monitoring 1999-2001.the determination of hepatic ethoxyresorufin o-deethylase (erod) has been used to assess the induction of the mixed function oxygenase system (mfo) of flounder (platichthys flesus) in uk estuaries. induction of the mfo system denotes possible exposure to certain organic contaminants (e.g. polycyclic aromatic hydrocarbons, polychlorinated biphenyls) and its measure has been incorporated in national monitoring programmes. this study presents erod monitoring data from 5 uk estuaries taken between 1 ...200415234875
dna adduct analysis and histopathological biomarkers in european flounder (platichthys flesus) sampled from uk estuaries.the presence of genotoxic and potentially carcinogenic chemical contaminants in the estuarine and coastal marine environment is well documented. in this study, european flounder (platichthys flesus) sampled from eight uk estuaries were analysed for hepatic dna adducts, using the 32p-postlabelling assay and liver histopathology as part of an on going survey to establish the health status of uk estuaries. fish were collected from the estuaries tyne, mersey, thames, alde (reference site), belfast, ...200415288550
bile metabolites of polycyclic aromatic hydrocarbons in three species of fish from the severn estuary.six metabolites of polycyclic aromatic hydrocarbons (pahs) were identified and quantified from the bile of 31 common eels (anguilla anguilla), 29 european flounders (pleuronectes flesus), and 15 conger eels (conger conger) collected from the severn estuary and bristol channel during 1997. the bile metabolites were deconjugated by enzymatic hydrolysis and separated by reverse-phase hplc with fluorescence detection. the major metabolite present in all fish was 1-hydroxy pyrene (75-94% of all metab ...200211886183
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