| experimental transmission of wuchereria bancrofti to monkeys. | infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ... | 1979 | 107818 |
| japanese encephalitis virus in northern taiwan, 1969-1973. | sentinel pigs were bled and mosiquitoes were collected for isolation of japanese encephalitis virus (jev) between 1969 and 1973 in a rural area of northern taiwan which reported a high annual incidence of human cases. the study site included a farmyard, schools, a bat cave, rice paddies and a heronry. although culex annulus was collected in every month of the year, isolations were made only in midsummer and only from culex annulus and (once) from culex tritaeniorhynchus. these isolates were usua ... | 1976 | 180845 |
| infection of newborn taiwan monkeys (macaca cyclopis) with human adenovirus type 12 and simian virus 40. | for testing biological response of newborn taiwan monkeys to infection of human adenovirus type 12 (ad12) and simian virus 40 (sv40), 40 newborn taiwan monkeys were inoculated with ad12, ad12, plus sv40, ad12 supplemented with ad12-induced hamster tumor tissue (ad12 tumor) or control specimens (hela or african green monkey kidney cell lysate). among them 26 survived including 8 newborn monkeys inoculated with control specimens. the survivors were observed for 4 years but no tumor was produced. t ... | 1975 | 181217 |
| host preference of mosquito vectors of japanese encephalitis. | the host preference of 4 culex mosquito species collected in miaoli and pingtung counties, taiwan was studied by capillary precipitin method. antisera to alum-precipitated sera of man, bovine, swine, rabbit, horse, dog, cat, mouse, chicken, duck, and pigeon were produced in rabbits and reacted with 758 mosquito blood meals among which reactions to one or more antisera. culex annulus and culex tritaeniorhynchus summorosus showed a great avidity for pig, and culex fuscocephala for bovine. culex pi ... | 1975 | 181218 |
| homology of epstein-barr virus dna in nasopharyngeal carcinomas from kenya, taiwan, singapore and tunisia. | | 1975 | 191360 |
| auto-antibodies in the sera of patients with nasopharyngeal carcinoma. | | 1975 | 191369 |
| clustering of different subtypes of hepatitis b surface antigen in families of patients with chronic liver diseases. | clustering of hepatitis b surface antigen (hbsag) with both subtypes adr and adw in three families of patients with chronic liver diseases or hepatocellular carcinoma was demonstrated in taiwan where adw is the main subtype. the subtype in the children was similar to that in their mothers, suggesting maternal transmission. in all the family units clustered with different subtypes, the same pattern occurred, invariably with fathers carrying hbsag/adr and the children carrying hbsag/adw. the subty ... | 1978 | 210659 |
| histopathological types of nasopharyngeal carcinoma in a low-risk area: japan. | npc in japan was studied histopathologically by examining 816 npcs from among 3 338 biopsies from patients with tumours of the nasopharynx and other parts of the upper respiratory system. in addition, a comparative study on npc among taiwanese and an immunoserological study were carried out. when comparing histological types of malignant tumours of the upper respiratory tract, poorly-differentiated squamous-cell carcinoma predominated only in those of the nasopharynx. malignant nasopharyngeal tu ... | 1978 | 215515 |
| interaction of factors associated with cancer of the nasopharynx. | a retrospective study of nasopharyngeal carcinoma (npc) revealed that smoking, working under poor ventilation, use of nasal balms or oil for nasal and throat troubles, use of herbal drugs, and anti-ebv antibody titer were found statistically associated. the dural interactions of these factors to the risk of npc were presented. except in work conditions with poor ventilation and when herbal drugs are used, all the combinations were synergistic. the synergistic actions were especially remarkable w ... | 1979 | 227565 |
| serologic survey for human babesiosis on taiwan. | | 1977 | 273657 |
| a study on pesticide residues in umbilical cord blood and maternal milk. | | 1976 | 1068219 |
| the phenotype and gene frequencies of human platelet specific antigens among chinese in taiwan. | human platelet specific antigens (hpa) were serologically typed among 48 to 567 samples of blood from chinese in taiwan by using the mixed passive hemag-glutination method (mpha). the prevalence found was: hpa-la (p1a1), > 99.9% (48/48); hpa-2b (koa or siba), 9.0% (51/567); hpa-3a (baka), 84.8% (481/567); hpa-4a (yukb), > 99.9% (567/567); hpa-4b (yuka), 0.5% (3/567); hpa-5b (br(a)), 32.6% (185/567); and nak(a), 98.4% (558/567). the gene frequencies for these antigens were: hpa-la (p1a1), > 0.999 ... | 1992 | 1306149 |
| sequence analysis of the bzlf 1 gene of epstein-barr virus derived from a new variant isolated in taiwan. | | 1992 | 1310809 |
| distribution of type a and type b ebv in normal individuals and patients with head and neck carcinomas in taiwan. | the subtypes of epstein-barr virus (ebv) according to the ebna 2 gene were investigated in taiwan by the polymerase chain reaction (pcr) and by southern blot hybridization. the materials included 53 nasopharyngeal carcinoma (npc) biopsies, 49 other head and neck cancers and 32 throat washings of normal individuals. ebv dna was found in all npc biopsies, 27 of 49 other head and neck carcinomas and 81% of normal individuals. type a ebv was the predominant type of ebv in both normal individuals and ... | 1992 | 1322927 |
| fireside conference 16. nasopharyngeal carcinoma. | | 1992 | 1327018 |
| prevalence of antibody to epstein-barr virus dnase in children. | antibodies to epstein-barr-virus-specific dnase in children under 15 years old from taipei, taiwan were determined by an enzyme neutralization test. serum was taken as positive for the anti-dnase antibody when 1 ml of serum could neutralize > or = 2 units of the dnase activity. among the 1,292 sera tested, 5.6% of the children were shown to have anti-ebv dnase antibodies, a result similar to that for adults. maternal antibodies against the ebv dnase were found to decrease very rapidly 2 months a ... | 1992 | 1339186 |
| seroepidemiology of cytomegalovirus infection among children between the ages of 4 and 12 years in taiwan. | to determine risk factors responsible for primary cytomegalovirus (cmv) infection in taiwan, samples of blood for antibody to cmv were obtained from 362 children aged 4 to 12 years: 58% were found to be positive for anti-cmv igg antibody. logistic regression analysis showed that seropositivity correlated with age, method of delivery, duration of breast feeding, and younger age of mother. neither socioeconomic status nor crowded living conditions showed significant correlation with cmv seropositi ... | 1992 | 1320100 |
| pregnancy after transfer of frozen-thawed human embryos. | cryopreservation of human embryos has been successfully applied in in vitro fertilization (ivf) and embryo transfer (et) programs at the national taiwan university hospital since 1988. our preliminary results with 120 frozen-thawed embryos in 31 transfer cycles showed that the survival rate of frozen embryos was 66%. following transfer, the implantation rate and clinical pregnancy rate were 6.5% and 13%, respectively. four clinical pregnancies and one preclinical pregnancy following a frozen-tha ... | 1992 | 1360300 |
| commercialization of biotechnology in the asian region. report of meeting of asian productivity organization (apo) in osaka, japan. | detailed studies on the commercial development of biotechnology in five countries in the asian region (viz. japan, korea, taiwan, thailand, india) indicate a very significant role played by government in strategic planning and r & d financing. strong growth is projected in some traditional biotechnology products e.g. amino acids such as monosodium glutamate and l-lysine, animal and human vaccines, and in environmental applications of biotechnology. the cash flow from these products will underpin ... | 1990 | 1369443 |
| [isolation and characterization of a new picornavirus in taiwan]. | during the 1971 outbreaks of acute hemorrhagic conjunctivitis, 298 cases were admitted to the veterans general hospital and seven strains of new picornavirus were isolated in human epidermoid carcinoma cells. two strains of the virus isolated have been further studied. serological neutralization indicated that these isolates might represent a distinct picornavirus group. biophysical and biological properties determined by this study indicated that the viruses had many characteristics in common w ... | 1975 | 1243761 |
| longitudinal studies on adipose tissue and its distribution in human subjects. | on 27 men and 6 women, total body density and 10 skinfolds were measured 12 yr apart, with the mean age increasing from 31 to 43 yr. the increase in skinfold thickness was found to be related to the increase in total body adiposity, calculated from hydrostatic weighing. the external adipose tissue was calculated from the mean skinfold thickness and body surface area. variations in total adiposity among the population studied as well as changes in total adiposity with age showed a characteristic ... | 1975 | 1184522 |
| longitudinal measurements of blood volume and essential body mass in human subjects. | repeated determinations of blood volume and body density were made on 34 chinese subjects (28 men and 6 women) in taiwan over a period of 12 yr, as the mean age increased from 31 to 43 yr. essential body mass calculated from body density and body weight showed no significant change over the 12-yr period. changes in body weight (mean gain equals 6.0 kg) were attributable to alterations in adipose tissue weight, the density of which was found to be 0.948 g/cm3. in two-thirds of the subjects the se ... | 1975 | 1184521 |
| radiculomyelitis following acute haemorrhagic conjunctivitis. | the clinical manifestations and natural history of radiculomyelitis following a newly reported disease--acute haemorrhagic conjunctivitis (ahc)--have been studied in 33 patients in taiwan, and the following observations made: all the patients in this series were adults at ages ranging from 21 to 55 years; the salient initial neurological manifestations were radicular pains and acute flaccid paralysis which developed from five to thirty-seven days after the onset of ahc. in some patients, signs a ... | 1976 | 1030657 |
| epidemic appearance of a new influenza strain in asia. | an outbreak of influenza associated with increased absenteeism among school-age children occurred during may and june 1975 in tapei, taiwan. the virus strain has recently been shown to be antigenically similar to a/victoria/3/75 which is now active in other areas of the pacific. | 1976 | 1027110 |
| drug resistance and plasmid profile of shigellae in taiwan. | one hundred and twenty-eight shigella strains isolated from newborn and infant human faecal specimens at kaohsiung medical college hospital in taiwan were serogrouped, serotyped and examined for drug-resistance patterns and for the presence of plasmids. forty-seven per cent of the isolates were found to belong to the shigella sonnei serogroup, 41% to the s. flexneri group, 9% to the s. boydii group and 3% to the s. dysenteriae group. the serotype with the greatest number of strains was s. sonnei ... | 1992 | 1547844 |
| influenza virus isolations from dogs during a human epidemic in taiwan. | during an islandwide outbreak of human influenza in june and july 1971, throat swabs were taken from dogs and cats in 3 urban communities of taiwan. eight influenza isolates were obtained from dogs in july 1971: two were identified as influenza a closely related to the human hong kong/68 virus, and one was a strain of influenza type b closely resembling human influenza b virus. the latter is the first such reported isolation from dogs under natural conditions. | 1976 | 977232 |
| a surveillance of human influenza virus in swine in southern taiwan. | from september 1970 to december 1971, samples were taken monthly from farm pigs, piglets and abattoir pigs in southern taiwan for virus isolations and serologic studies. a total of 10 strains of hemagglutinating agent were isolated in january and july 1971, following 2 epidemics of human influenza occurring in december 1970 and june 1971, respectively. three strains were antigenically confirmed as influenza a similar to a/hong kong/68 virus. | 1977 | 885670 |
| a pathologic study of childhood lymphoma in taiwan with special reference to peripheral t-cell lymphoma and the association with epstein-barr viral infection. | the authors retrospectively reviewed the clinicopathologic and immunologic features of 65 consecutive cases of childhood lymphoma reported between 1980 and 1989. southern blot hybridization was also performed in 23 cases to study their association with epstein-barr virus (ebv) and human t-cell leukemia virus type 1 (htlv-1). the 65 cases included 56 non-hodgkin's lymphoma (nhl) (86%) and 9 hodgkin's disease (hd) (14%). the nhl could be classified into the following groups: group i, small nonclea ... | 1991 | 1655230 |
| excess mortality and influenza surveillance in taiwan. | excess mortality has proven to be a useful epidemiologic tool for influenza surveillance in the temperate zone. a retrospective analysis of the epidemiology of influenza in taiwan was undertaken to explore the usefulness of this technique in the tropical--subtropical zone. excess mortality similar to that observed during influenza epidemics in the temperate zone was noted during periods of previously recognized influenza epidemics in taiwan. for the very young and the elderly excess mortality wa ... | 1978 | 721357 |
| schistosoma mekongi sp. n. from man and animals, compared with four geographic strains of schistosoma japonicum. | schistosoma mekongi sp. n. is described from man and animals in cambodia. it is compared to 4 geographic strains of schistosoma japonicum. it differs from s. japonicum in the size of embryonated eggs, in the length of the prepatent peroid in the mammalian host, and in its utilization of a different snail host. the relative usefulness of conventional morphologic criteria in the differentiation of asian schistosomes is discussed. | 1978 | 682060 |
| activation analysis of mercury in urine samples of electrolysis cell workers. | the activation method of determination of trace amounts of hg in human urine has been studied by introducing a simple amalgam deposition method. human urine samples were obtained from the alkali chloride, electrolysis plant equipped with hg cells. the capacity of cu powder for hg quantity, the ph conditions, and the shaking time were described. the results showed that the hg contents in workers' urine samples varied from 33 ppb to 60 ppb depending on working conditions. | 1977 | 578969 |
| antibodies to epstein-barr virus capsid antigen and early antigen in nasopharyngeal carcinoma and comparison groups. | antibodies to epstein-barr virus capsid antigen (anti-vca) and early antigen (anti-ea) were measured in 263 patients with nasopharyngeal carcinoma (npc), 624 age- and sex-matched neighborhood controls, 570 family members of npc patients and 830 family members of neighborhood controls in taiwan. the distribution of antibody titers was significantly different between npc patients and the other three groups. more than 55% and 45% of npc patients had titers of greater than or equal to 1:640 and grea ... | 1977 | 199059 |
| nasopharyngeal carcinoma in young patients. | we have reviewed retrospectively the records of 157 patients, less than or equal to 30 years of age with nasopharyngeal carcinoma (npc) from 218 such cases identified in the tumor registry files of three major teaching hospitals in taipei, taiwan. these cases were diagnosed between 1 january 1982 and 31 december 1985, with a minimum follow-up of 2 years. the average age was 25, with a male/female ratio of 1.67. the tnm (tumor size, nodes, metastases) classification of 127 patients showed t1, 22% ... | 1991 | 1846256 |
| relative importance of viruses and bacteria in the etiology of pediatric diarrhea in taiwan. | | 1977 | 198481 |
| geographical distribution of the subtype of hepatitis b surface antigen in chinese. | using the much more sensitive hemagglutination inhibition assay for subtyping of hepatitis b surface antigen (hbsag), we examined the determinants a, d, w and r in 192 from 228 hbsag positive adults who had been found after screening with reversed passive hemagglutination method. sixty-four subtypable cases were asymptomatic carriers and the remaining 128 were liver disease patients. among them there was no significant difference of the subtypes, invariably with adw as the main subtype. geograph ... | 1977 | 196971 |
| comparison of some methods for the detection of antigen-antibody reactions in amoebiasis. | the indirect hemagglutination test (iha) and counterimmuno-electrophoresis (cie) were used to test for antibodies to entamoeba histolytica in human sera using antigens from axenic cultures of the hk9 strain. correlation between the test was excellent with most sera from patients with amoebiasis demonstrating precipitin lines by cie at iha titers considered diagnostically positive, larger than or equal to 1:128. precipitin reactions with positive sera were also compared by cie, immunoelectrophore ... | 1976 | 193204 |
| htlv-1-associated myelopathy: first case reported in taiwan. | taiwan is geographically, culturally, and socially close to southern japan, which is an endemic area of human t-lymphotropic virus type 1-associated myelopathy (ham). taiwan, however, is not an endemic area of ham. we report the first case of ham in a native taiwanese, a 61-year-old woman, without known htlv-1 risk factors. | 1991 | 1950470 |
| viral hepatitis: some thoughts and a summary. | | 1975 | 192078 |
| fatal primary epstein-barr virus infection masquerading as histiocytic medullary reticulosis in young children in taiwan. | we reported 3 fatal cases of primary epstein-barr virus (ebv) infection resembling histiocytic medullary reticulosis (hmr) in young children in taiwan, where an hmr-like illness has been previously found to be prevalent. the disease ran a fulminant course, manifesting as fever, anemia, jaundice, skin rash, pulmonary infiltration, and/or hepatosplenomegaly lasting for only 1-3 weeks. laboratory tests revealed no hemolytic anemia and coombs test was negative. sepsis or hmr was the main clinical di ... | 1990 | 1963624 |
| japanese encephalitis surveillance in china (province of taiwan) during 1968-1971. i. geographical and seasonal features of case outbreaks. | during 1968-1971 japanese encephalitis (je) surveillance was conducted with who-assisted programs in taiwan area. emphasis was placed on: (1) active case-finding by hospital visits; (2) blood collection from every patient at the suitable time; and (3) the enforcement of standard diagnostic criteria on the results of hemagglutination-inhibition tests. each year, approximately 90% of reported patients were etiologically examined. je virus etiology was established in 277 (1968), 279 (1969), 269 (19 ... | 1975 | 180319 |
| evidence against breast-feeding as a mechanism for vertical transmission of hepatitis b. | a follow-up study of 147 babies born to mothers known to be carriers of hepatitis b surface antigen (hbsag) revealed no evidence for a relationship between breast-feeding and the subsequent development of antigenaemia in the babies. all babies were tested at three or more months of age, and the mean age at last follow-up was eleven months with a mean of three serum specimens per baby (not counting cord-blood specimens). the frequency of acquisition of hbsag and anti-hbs was almost identical amon ... | 1975 | 52772 |
| specific restriction fragment length polymorphism in liver mitochondrial dna of the chinese. | by use of restriction fragment length polymorphism analysis, we examined the liver mitochondrial dna amplified by polymerase chain reaction from 60 chinese subjects of 31 to 78 years of age. we found nine specific mtdna polymorphisms that had never been reported before. eleven subjects had an alu i polymorphic site in the subunit 2 gene of nadh dehydrogenase, five had a hae iii polymorphic site in the cytochrome oxidase subunit 2 gene, and five had a hinf i polymorphic site in the subunit 3 gene ... | 1992 | 1358420 |
| [kaposi's sarcoma in tainan: report of five cases]. | kaposi's sarcoma (ks) is an uncommon cutaneous neoplasm with an increased incidence among jews and italians of europe and north america and negroes of equatory africa. in recent years, several cases have been diagnosed in aids patients and in patients who have undergone organ transplantation or received immunosuppressant treatments. we have diagnosed five cases of ks over a 3-year period in our department. they include four men and one women, aged from 58 to 79 years, and who were born and had l ... | 1992 | 1358363 |
| pericentric inversions of chromosome 9 in taiwanese fetuses. | using trypsin-giemsa banding, a total of 1,350 unrelated chinese fetuses were studied for pericentric inversion of chromosome 9 [inv(9) (p11; q13)]. sixteen cases (1.2%) were found to have this variant. the prevalence was higher than that in a previous report on asians. all the fetuses with inv(9) were born with a normal phenotype. | 1992 | 1358322 |
| cryptococcus albidus isolated from pigeon excreta in taiwan. | cryptococcus albidus (saito) skinner, found frequently in the air of el-minia, egypt; in new zealand and budapest, and isolated occasionally from clinical specimens, has now been recognized as the cause of human diseases. since isolation of this fungus from pigeon droppings has not previously been reported, this first paper reports results of its drug-susceptibility testing to gentamicin and 5-fluorocytosine, as well as its fungal cell antigenic cross reactivity with c. neoformans as detected by ... | 1992 | 1342644 |
| evaluation of anti-htlv-1 in physical-checkup individuals and blood donors in taiwan. | the gelatin particle agglutination (gpa) test specific for antibody detection of human t-cell lymphotropic virus type 1 (htlv-1) was used to screen 500 blood donors and 5000 physical-checkup individuals at veterans general hospital-taipei. the positive rate of physical-checkup individuals and the blood donors was 0.18% (9/5000) and 0% (0/5000) respectively. among the 9 gpa positive specimens, eight were confirmed to be positive by western blot analysis and a prevalence rate of 0.16% (8/5000). se ... | 1992 | 1342641 |
| risk factors linked to tumor recurrence of human hepatocellular carcinoma after hepatic resection. | a total of 238 patients who received curative hepatic resections during the last 10 yr were observed to search for the risk factors linked to early tumor recurrence of human hepatocellular carcinoma after hepatectomy. the results revealed that tumor size, tumor appearance and dna ploidy were the factors in predicting tumor recurrence after resection for hepatocellular carcinoma. patients with a tumor size less than or equal to 5 cm or a tumor appearance of the solitary type had better disease-fr ... | 1992 | 1332922 |
| molecular characterization of glucose-6-phosphate dehydrogenase (g6pd) deficiency by natural and amplification created restriction sites: five mutations account for most g6pd deficiency cases in taiwan. | we have developed a rapid and simple method to diagnose the molecular defects of glucose-6-phosphate dehydrogenase (g6pd) deficiency in chinese in taiwan. this method involves the selective amplification of a dna fragment from human g6pd gene with specific oligonucleotide primers followed by digestion with restriction enzymes that recognize artificially created or naturally occurring restriction sites. ninety-four chinese males with g6pd deficiency were studied. the results show that 50% (47 of ... | 1992 | 1323345 |
| hepatitis c virus infection in an area hyperendemic for hepatitis b and chronic liver disease: the taiwan experience. | to assess the contribution of hepatitis c virus (hcv) in liver disease in taiwan, antibody to hcv (anti-hcv) was studied by radioimmunoassay in 392 patients with chronic liver disease and in 440 healthy adults and 444 subjects at risk. the anti-hcv prevalence was 0.95% in 420 volunteer blood donors, 90% in 100 hemophiliacs, and 81% in 58 parenteral drug abusers. anti-hcv was present in 6 (7.7%) of 78 hepatitis b surface antigen (hbsag)-positive and 28 (65%) of 43 hbsag-negative patients with chr ... | 1990 | 2169497 |
| rapid diagnosis of beta-thalassemia mutations in chinese by naturally and amplified created restriction sites. | we developed a rapid and simple method to diagnose the molecular defects of beta-thalassemia in chinese patients. this method involves the selective amplification of a dna fragment from human beta globin gene with specific oligonucleotide primers, followed by digestion with restriction enzymes that recognize artificially created or naturally occurring restriction sites. to detect the 4-nucleotide deletion of codon 41-42, we introduced a single mismatch nucleotide into the 3' end of the upstream ... | 1992 | 1391961 |
| status and trend of hiv-1 infection and aids in taiwan, december, 1991. | from may 1, 1985 to december 31, 1991, a total of 4,962,707 serum samples from 8 population groups in taiwan were tested for anti-human immunodeficiency virus type 1 (anti-hiv-1). in total, 256 samples were seropositive; of these individuals, 43 developed acquired immunodeficiency syndrome (aids): 29 were homosexuals; 5 were hemophiliacs; 8 were heterosexuals and 1 was of unknown risk. although the prevalence of hiv-1 infection and aids remains low compared with other countries, since 1988 the i ... | 1992 | 1418187 |
| the incidence of fulminant hepatic failure in acute viral hepatitis in taiwan: increased risk in patients with pre-existing hbsag carrier state. | the incidence of fulminant hepatitis in taiwan was studied in a series of consecutive 523 patients with acute viral hepatitis including 11 with acute hepatitis a, 67 with acute hepatitis b, 124 with acute hepatitis nanb and 321 acute hepatitis in hbsag carriers (patients who were hbsag positive but anti-hbc igm negative). thirty-eight (7.3%) were recognized as fulminant hepatitis. the incidence of fulminant hepatitis was relatively low in patients with acute hepatitis a, b or nanb (2.0% or 4 out ... | 1990 | 2210850 |
| diagnosis of glucose-6-phosphate dehydrogenase (g6pd) mutations by dna amplification and allele-specific oligonucleotide probes. | we have recently identified that at least four types of mutation are responsible for the glucose-6-phosphate dehydrogenase (g6pd) polymorphism in the chinese of taiwan. two mutations (487 g-->a and 493 a-->g) occurring at nucleotide position 487 and 493, respectively, create alu i and ava ii recognition sites which enabled us to directly examine these two mutations by pcr/restriction enzyme (re) digestion. however, the other two mutations (1376 g-->t and 1388 g-->a), which do not generate any re ... | 1992 | 1466205 |
| sexual patterns and human immunodeficiency virus infection among homosexuals in taiwan. | between 1988 and 1991, 64 homosexual men and 43 bisexual men were screened for human immunodeficiency virus (hiv) in southern taiwan; 5 of them were found to carry hiv antibodies. according to a self-administered questionnaire completed before screening, the average age of the men in the study group was 27 years, and the average duration of practiced homosexuality was 3.8 years. occupations included student, merchant, laborer, officer, and soldier, and many of the men (45/107) had some junior co ... | 1992 | 1492260 |
| hla antibodies--the cause of platelet alloimmunization in chinese. | lymphocytotoxicity test (lct) and platelet suspension immunofluorescence test (psift) were used together to screen platelet-associated antibodies in patients who received long-term platelet transfusion. twenty-four of 53 patients (45.3%) were immunized subsequently. since the concordance of lct and psift was 100%, most of the platelet associated antibodies were of hla specificity, and platelet specific antibody alone (in absence of hla) was not detected. the identified antibodies were anti-a2, a ... | 1992 | 1536138 |
| diverse point mutations result in glucose-6-phosphate dehydrogenase (g6pd) polymorphism in taiwan. | glucose-6-phosphate dehydrogenase (g6pd; ec 1.1.1.49) deficiency is the most common human enzymopathy, affecting more than 200 million people worldwide. although greater than 400 variants have been described based on clinical and biochemical criteria, little is known about the molecular basis of these g6pd deficiencies. recently, the gene that encodes human g6pd has been cloned and sequenced, which enables us to examine directly the heterogeneity of g6pd at the dna level. during the past 10 year ... | 1992 | 1562739 |
| a new threat to public health: organochlorines and food. | ambient levels of persistent toxic chemicals, chemicals that persist for decades in the environment, have reached levels high enough to affect the health of children. the organochlorines (pcbs, ddt and the dioxin family) accumulate in human adipose tissue. pregnant women pass the contamination to their fetuses. the developing nervous system is the most vulnerable. neurobehavioral deficits, including short-term memory loss, are detected in children born to mothers at the high end of the distribut ... | 1992 | 1603449 |
| prevalence of antibodies to hepatitis c virus (anti-hcv) in different populations in taiwan. | the prevalence of antibodies to hepatitis c virus (anti-hcv) was investigated among different populations in taiwan, where anti-hcv was detected in 0.8% (24/2,994) of adult volunteer blood donors, 0.1% (1/1,305) of youngsters and children, 12.5% (8/64) of adult volunteer blood donors with elevated alanine aminotransferase (alt), 36.5% (23/63) of hemodialysis patients, 4.1% (13/318) of male homosexuals, 25.4% (16/63) of cases positive for antibodies to human immunodeficiency virus (anti-hiv), 82. ... | 1991 | 1657545 |
| esterase d and retinoblastoma gene loci are tightly linked to wilson's disease in chinese pedigrees from taiwan. | wilson's disease (wd) is a rare autosomal recessive disorder and has been mapped to the long arm of chromosome 13 (q14.1). we have analyzed the segregation of esterase d (esd) and retinoblastoma (rb) gene loci in ten families of chinese wd subjects living in taiwan. the polymorphic information content (pic) for esd and rb was 0.18 and 0.31, respectively. we confirmed a tight linkage between these loci and wd with a lod score of 3.33 by multipoint linkage analysis. the data from this limited numb ... | 1991 | 1679032 |
| analysis of allergenic components of bermuda grass pollen by monoclonal antibodies. | a panel of 16 monoclonal antibodies (moabs) directed against bermuda grass (cynodon dactylon) pollen (bgp) were generated for identification and purification of the major allergenic components of the eliciting antigen (ag). radioimmunoprecipitation (rip) analysis revealed that there were at least eight antigenic components with molecular weights (mw) ranging from 12 kilodalton (12 kda) to 200 kda. each of these components has distinct biochemical characteristics based on sodium dodecyl sulfate-p ... | 1991 | 1796777 |
| clonorchiasis in taiwan. | since ohi in 1915 found clonorchiasis patients in taiwan, many surveys have shown that miao-li in the north, sun-moon lake in the middle and mei-nung in the south of taiwan are three important endemic areas of clonorchiasis. in recent studies, the disease showed a tendency to extend its endemicity. rats, cats, dogs and pigs are the natural reservoir hosts, and 17 species of fresh water fish are also infected with metacercaria. one definitive snail host, parafossarulus manchouricus, and two other ... | 1991 | 1822883 |
| [production and characterization of monoclonal antibody against colon cancer associated antigen in chinese]. | although many monoclonal antibodies have been made in human colon cancer, none of them are from the chinese species. recently, a colon cancer cell line cc-m2 established from a chinese patient has been completely characterized and used as immunogen to produce monoclonal antibodies. monoclonal antibodies were produced by standard hybridoma technique. the fusion rate was 95.8%. an isotype igg1 of high proliferation named as sam-2 was used in this study. the titers were measured around 10(4). furth ... | 1991 | 1848460 |
| antibody to epstein-barr virus-specific dnase as a marker for field survey of patients with nasopharyngeal carcinoma in taiwan. | a serological survey using antibody to epstein-barr virus (ebv)-specific dnase activity as a marker for the identification of patients with nasopharyngeal carcinoma (npc) has been carried out on healthy subjects who visited government employees' clinic center (gecc) for routine health examination and on individuals residing in npc high-risk areas (hra) in taiwan. during a 3-year prospective study, 22,596 and 9,869 sera were collected from the gecc and hra groups, respectively. taking neutralizat ... | 1989 | 2542436 |
| seroepidemiology of hepatitis c virus infection in taiwan. | the prevalence of antibody to hepatitis c virus among chinese subjects in taiwan was evaluated using a commercially available enzyme immunoassay. the overall prevalence of antibody to hepatitis c virus was 0.28% among 1,419 healthy subjects, 0.8% among 500 unselected paid blood donors and 0.4% among 793 pregnant women. the three offspring of the mothers positive for antibody to hepatitis c virus were all found to be positive for antibody to hepatitis c virus at birth but all became negative by t ... | 1991 | 1851491 |
| molecular epidemiology and restriction site mapping of adenovirus type 3 genome types. | one hundred thirty-eight strains of adenovirus type 3 isolated from patients in the united states, west germany, and other regions between 1961 and 1984 were analyzed with six restriction endonucleases; 18 genome types were found. bglii was the most discriminative enzyme. mapping of altered restriction sites was also performed for all six enzymes. the genome types d1 (like the prototype) and d3 prevailed among 45 and 47 strains, respectively. all genome types could be divided into two groups rel ... | 1989 | 2546977 |
| an intercultural assessment of the type, intensity and number of crisis precipitating factors in three cultures: united states, brazil and taiwan. | the precipitating factors of crisis have cultural interpretations that make diagnostic criteria and intervention methods ethnologically different. the crisis precipitating factors of individuals seeking intervention in the republic of china (taiwan), brazil and the united states (u.s.) were investigated toward the end of isolating correlates and discrepancies of ethnic-related precipitants of crisis. the primary objective of the study was to influence crisis intervention in the profession of nur ... | 1991 | 1938179 |
| seroepidemiological study of epstein-barr virus infection in children in taipei. | serumigg antibody titer against viral capsid antigen(vca) of epstein-barr virus (ebv) was measured by indirect immunofluorescence antibody method in 1350 children under 15 years of age, 723 males and 627 females, who were living in the taipei area. sera were collected from june through october 1984. under the age of 6 months, the prevalence rate of positive serum vca antibody was 38.4%. it decreased to 6.4% between 6 and 12 months of age, but rose to 65.8% during the second year of life. the rat ... | 1989 | 2561579 |
| histiocytic medullary reticulosis: a lethal form of primary ebv infection in young children in taiwan. | | 1989 | 2563546 |
| human t-cell lymphotropic virus type i associated adult t-cell leukaemia/lymphoma in taiwan chinese. | twenty-five chinese patients with human t-cell lymphotropic virus type i (htlv-i) associated adult t-cell leukaemia/lymphoma (atll) were identified in taiwan. no patients had been outside taiwan and none were descendants of japanese heritage. their ages ranged from 28 to 71 years. there were 17 men and eight women. main clinical and laboratory features at presentation were lymphadenopathy (16), skin lesions (11), hepatosplenomegaly (11), pulmonary lesions (11), hypercalcaemia (10) and bone marro ... | 1991 | 1958472 |
| community-wide epidemiological investigation of a typhoid outbreak in a rural township in taiwan, republic of china. | an outbreak of typhoid fever occurred in chu-tung township, taiwan, with dates of onset from 6 july to 8 august, 1983. fifty-four cases were hospitalized, of which 52 were laboratory confirmed. a chloramphenicol-resistant strain of salmonella typhi was isolated from patients' blood samples. a community survey of 2772 people selected from 490 households by stratified systematic cluster sampling, presented an attack rate of 9.4 per 1000 and a case reporting rate of 10%. the attack rate was higher ... | 1989 | 2656560 |
| restriction fragment length polymorphisms at the ornithine transcarbamylase locus in normal chinese. | ornithine transcarbamylase (otc) (ec 2.1.3.3) is an hepatic mitochondrial enzyme involved in the detoxication of ammonia; it catalyzes the second step of the urea cycle, and is x-linked in human beings. deficiency of otc results in ammonia intoxication and, often, in early infant death, especially in males. this report describes the use of a nearly full-length cloned human cdna for otc for southern blot analysis of genomic dna. the pattern of mspi, taqi, hindiii and ecori restriction endonucleas ... | 1990 | 1979899 |
| counterimmunoelectrophoresis test on human clonorchis sinensis infection. | a counterimmunoelectrophoresis test was used to detect antibodies against the adult worm antigen of clonorchis sinensis in sera from 70 clonorchiasis patients, 20 uninfected healthy persons and 7 patients infected with other helminths. a constant voltage of 10 v/cm and a running time of 30 minutes was chosen in carrying out detection. antibody titers of 1, 1:2 and 1:4 were obtained from 35, 21 and 14 clonorchiasis patients, respectively. significant correlation was observed between worm burden i ... | 1989 | 2699087 |
| polymorphic locus in the 5'-flanking region of human insulin gene and non-insulin-dependent diabetes mellitus. | the etiology of non-insulin-dependent diabetes mellitus (niddm) is still unclear, but appears to involve some genetic factors. there have been disputes over the association between dna sequences flanking the insulin gene and niddm. in order to characterize insulin gene polymorphism in the chinese population and elucidate its association with niddm, 100 unrelated chinese subjects living in taiwan were observed for polymorphism of this hypervariable region. most of them were descendants of immigra ... | 1990 | 1982127 |
| molecular lesion in chronic granulocytic leukemia is highly conserved despite ethnic and geographical variation. | leukemic cell dna from patients with philadelphia chromosome positive chronic granulocytic leukemia in the united kingdom, taiwan, and south africa and of diverse ethnic origins all have identifiable molecular rearrangements of the breakpoint cluster region on chromosome 22 band q11 when screened with an appropriate dna probe. this result reinforces the highly conserved nature of the molecular lesion in chronic granulocytic leukemia and its suitability as a diagnostic marker for the disease. sin ... | 1987 | 2823024 |
| antibodies to epstein-barr virus-specific dnase in patients with nasopharyngeal carcinoma and control groups. | serum samples from 154 patients with nasopharyngeal carcinoma (npc), 374 with other cancers, 1,000 normal controls from government employees' clinic center (gecc), and 3,642 individuals of various ethnic-dialect groups living in high-risk areas for npc were collected and the concentration of antibodies to epstein-barr virus (ebv)-specific dnase activity was determined. taking a serum sample where 1 ml will neutralize two or more units of the dnase activity as positive, 2-4 units as low level, 4- ... | 1987 | 2824675 |
| anopheline mosquitoes and malaria parasites in taiwan. | extensive taxonomic studies of the genus anopheles were carried out in taiwan during the first half of the 20th century. as a result, 17 species of anopheles were identified and reported as occurring in taiwan. however, the occurrence of two species, an. kochi and an. fluviatilis, in taiwan is doubtful. vector competence of the anophelines of taiwan was also studied both in the laboratory and in the field during the same period of time, and experimental infections of 8 species of anopheles were ... | 1991 | 2056555 |
| a molecular study of adenovirus type 8 isolated from viral conjunctivitis in the kaohsiung area during 1983-1984: a chronological comparison of subtypes by endonuclease cleavage analysis. | | 1987 | 2838647 |
| isolation of dengue virus with a human promonocyte cell line. | in october-november, 1988 there was an outbreak of dengue fever in the kaoshiung area of southern taiwan. we collected 100 serum samples from 96 patients at the onset of their fever for virus cultures and identification. a human promonocyte cell line (hl-cz) established in our laboratory was used and proved to be susceptible for dengue virus propagation. type 1 dengue virus in the hl-cz cell culture was identified by immunofluorescence tests using monoclonal antibodies, and also by hemagglutinat ... | 1991 | 2063953 |
| the effect of fluorescent humic substances existing in the well water of blackfoot disease endemic areas in taiwan on prothrombin time and activated partial thromboplastin time in vitro. | fluorescent humic substances (fhs) in well water of blackfoot disease endemic areas were purified and fractionated by sephadex g-25 column chromatography. four fractions of the purified fhs were isolated. the purified fhs and their fractions were then added to normal human pool plasma in vitro separately to detect the abilities of the effects on prothrombin time (pt) and activated thromboplastin time (aptt). results showed that all of the four fractions of the purified fhs prolonged both pt and ... | 1990 | 2140208 |
| iron and the risk of cancer. | four epidemiological studies have been performed that are generally consistent with the hypothesis that increased available body iron stores increase the risk of cancer or of general mortality. in a study based on the first national health and nutrition examination survey in the united states (nhanes), 232 men who developed cancer over a ten year period had a mean transferrin saturation of 33.1% at least 4 years before diagnosis, whereas 3,113 men who did not develop cancer had a transferrin sat ... | 1990 | 2146450 |
| comparison of results of chinese and american forecasting of nursing curriculum needs. | this study used mengel's (1987) round three questionnaire results from the fellows of the american academy of nursing and baccalaureate nurse educators of taiwan to compare perceived importance of nursing curriculum needs. the t-test was used as a test of difference between the two groups. ninety-nine of 129 items were significantly different (p less than .05). this result showed that the forecasting of nursing curriculum needs between r.o.c. and the u.s. generic baccalaureate nursing faculty ar ... | 1990 | 2176681 |
| eradication of bancroftian filariasis by diethylcarbamazine-medicated common salt on little kinmen (liehyu district), kinmen (quemoy) islands, republic of china. | since bancroftian filariasis constituted a major public health problem on little kinmen (liehyu district), kinmen (quemoy) islands, a control programme was conducted on this island from 1970 to 1982. a pre-control survey recorded a microfilarial rate (mfr) of 9.6%, a night blood microfilarial density (mfd) of 14.4/20 microliters blood, and a clinical rate of 26.2%. culex quinquefasciatus was found to be the only vector of the parasitosis on the island, with an infection rate (ir) with all filari ... | 1990 | 2184787 |
| antibody response to epstein-barr-virus-specific dnase in 13 patients with nasopharyngeal carcinoma in taiwan: a retrospective study. | serum samples obtained from 13 individuals who were found to have a previous history of or to be suffering from nasopharyngeal carcinoma (npc) were examined for the presence of antibody to epstein-barr virus (ebv) dnase activity. significant to high levels of antibody to ebv dnase activity were detected in most serum samples obtained from four patients prior to the diagnosis of npc. the samples from the other nine patients showed variable levels of antibody. the majority of the samples collected ... | 1985 | 2989423 |
| serological survey of antibodies to the adult t-cell leukemia virus-associated antigen (htlv-a) in taiwan. | a serological survey of antibodies to the adult t-cell leukemia virus-associated antigen (htlv-a) conducted in taiwan revealed ii seropositive individuals among 2,565 serum donors tested, which included 1,187 hospital or free clinic patients, 1,065 blood donors and 313 aborigines. the overall prevalence rate was 0.43% and was 0.90% (9/995) for adults aged 40 years or over, which was similar to the rates observed in the non-endemic areas in japan. no highly prevalent area was demonstrated. the ii ... | 1985 | 2993172 |
| antibody to epstein-barr virus-specific dnase as a marker for the early detection of nasopharyngeal carcinoma. | we have previously shown that high levels of antibody to epstein-barr virus (ebv)-specific dnase may be a useful marker for the early diagnosis of nasopharyngeal carcinoma (npc). sera from 3,368 males in an area with a high risk for the development of npc were examined for the presence of antibody to ebv-specific dnase activity. significant levels of the antibody were found in 430 of these sera. as a result, 32 individuals have attended the out-patient department of otolaryngology for clinical e ... | 1985 | 2995572 |
| a survey of ampullarium canaliculatus for natural infection of angiostrongylus cantonensis in south taiwan. | ampullarium canaliculatus were collected monthly from the field in five areas in pintung county and examined for larvae of angiostrongylus cantonensis. snails from one area showed the highest positive rate (30.8%) and the highest number (31) of larvae per snail. snails were placed in four groups according to size. the positive rates in snails increased from 10.0 to 29.4% and the average number of larvae per snail increased from 11 to 40 as the size of snails increased from 1.0 to 4.0 cm height o ... | 1990 | 2231842 |
| a possible pathogenesis for blackfoot disease--effects of trivalent arsenic (as2o3) on cultured human umbilical vein endothelial cells. | blackfoot disease (bfd) is an endemic peripheral vascular occlusive disease found among the inhabitants of the southwest coast of taiwan. the clinical features of bfd are similar to those of buerger's disease. pathology shows arteriosclerosis obliterans and thromboangiitis obliterans. the high arsenic content of artesian well water in the area is regarded as the main causal factor of this disease. therefore, the purpose of this study was to observe the toxic effects of various arsenic concentrat ... | 1990 | 2273161 |
| [high incidence of tetanus in the middle-aged and elderly]. | tetanus is a disease which has a high mortality rate, caused by clostridium tetani. it presents with trismus, difficulty in swallowing, and more ominously difficulty in breathing, or opisthotonus. included in this retrospective study are 23 cases of tetanus treated in chang gung memorial hospital between jan. 1986 and dec. 1989. age ranged from 36 to 87, with the highest incidence in the middle-aged and elderly (91% older than 40 years of age). in 20 cases a wound was found as the source of infe ... | 1990 | 2282567 |
| hereditary pancreatitis in a chinese family. | in a chinese family with hereditary pancreatitis, two members are proven to have chronic pancreatitis. the propositus, a 31-year-old man, had epigastric pain since the age of 18. multiple calcifications in the region of the pancreas were seen on plain film of the abdomen, ultrasonography, computed tomography, and endoscopic retrograde pancreatography. pancreatolithotomy and side-to-side pancreatojejunostomy gave symptomatic improvement. his 60-year-old mother also had pancreatic calcifications i ... | 1990 | 2303690 |
| effects of formula protein level and ratio on infant growth, plasma amino acids and serum trace elements. i. cow's milk formula. | the optimum level and ratios of protein to be used in cow's milk formula has recently been under discussion. healthy term infants were fed from birth exclusively human milk or a formula that varied in protein level or whey: casein ratio: (a) 1.4 g/dl; 55:45, (b) 1.5 g/dl; 55:45, (c) 1.3 g/dl; 55:45, (d) 1.4 g/dl; 60:40, (e) 1.4 g/dl; 20:80. infants were followed for 12 weeks and blood samples were taken at 2, 4, 8 and 12 weeks. anthropometric indices did not show any significant differences amon ... | 1990 | 2333739 |
| post-hepatitic aplastic anaemia in children in taiwan, a hepatitis prevalent area. | aplastic anaemia is a rare but serious complication of hepatitis, and hepatitis is an unusual cause of aplastic anaemia in children in the west. however, the relative frequencies of acquired aplastic anaemia in children in taiwan, a hepatitis prevalent area, differ from those in the west, in the very high frequency of post-hepatitic aplastic anaemia (23.9% of all cases of aplastic anaemia). this may account for the higher incidence of aplastic anaemia in children in taiwan. although the prognosi ... | 1990 | 2346727 |
| the prevalence of anti-hcv among chinese voluntary blood donors in taiwan. | in taiwan, the prevalence of circulating anti-hcv is 2 percent among first-time voluntary chinese blood donors, 10 percent among donors with elevated alt levels (greater than 45 iu/l), and higher among older men. the carrier rate for hbsag was 18.6 percent and the frequency of positive hbv marker(s) (hbsag, anti-hbc, anti-hbs) was 86.4 percent among first-time donors. there is no significant correlation between hbv and hcv infections in taiwan, because there is no significant difference in the f ... | 1990 | 2360240 |
| exploring implicit personality theories with indigenous or imported constructs: the chinese case. | this study is concerned with the relation between indigenous and imported constructs of personality perception. a pool of chinese personality descriptors was used by chinese ss to rate a variety of target persons. these same ss then rated the same target persons using the (translated) personality descriptions first isolated by tupes and christal (1961) from americans. five factors of personality perception were then derived from both the emic chinese descriptors and the imported american descrip ... | 1990 | 2391641 |
| [lead exposure among kaohsiung traffic policemen]. | in this recent century there has been increasing concern over the possible harmful effects of lead from automobile exhaust on human health. traffic policemen are heavily exposed to automobile exhaust. in kaohsiung city because of the increasing number of motor vehicles due to rapid urbanization and heavy traffic transportation from suburbs for export trade, traffic policemen have varied exposure experiences. the automobile exhaust of lead additive gasoline was found to be the major type of expos ... | 1989 | 2476565 |
| changing aetiologic patterns of acute viral hepatitis in taiwanese children. | during 1981-86, 76 children were diagnosed as having acute viral hepatitis at the department of pediatrics, national taiwan university hospital, which is a major referral centre for hepatitis in children in northern taiwan. the majority (64%) of children had acute hepatitis b which had occurred mainly during infancy. perinatal transmission from a hepatitis b e negative surface antigen (hbsag) carrier mother or infection through blood transfusion from a donor who had escaped notice by a less sens ... | 1989 | 2535240 |
| high prevalence of human papillomavirus infection and possible association with betel quid chewing and smoking in oral epidermoid carcinomas in taiwan. | seventeen oral epidermoid carcinomas, three oral papillomas, and 17 normal gingival tissues were tested for the presence of human papillomavirus (hpv) types 6, 11, 16, and 18 sequences by southern blot hybridization. episomal hpv-16 sequences in various amounts were detected in 76.4% of the oral carcinomas and in all three cases of papilloma. however, only one of the 17 normal tissues was hpv positive with an unknown type. none of the samples contained hpv-6, -11, or -18 sequences. examination o ... | 1989 | 2542446 |
| differences between white and chinese populations in human leukocyte antigen sharing and gestational trophoblastic tumors. | the prevalence of gestational trophoblastic tumors varies widely among different populations: it is lowest in whites (3 to 6/100,000) and highest in chinese (68 to 202/100,000). this observation suggests that the origin of the disease is different in the two populations. to test this hypothesis, we examined couples in whom the woman developed a gestational trophoblastic tumor in a white population (pittsburgh) and a chinese population (taiwan) for sharing of human leukocyte a, b, dr, and dq anti ... | 1989 | 2552808 |
| [a review of larvivorous fish]. | recently, because of concern about the effects of insecticide on the environment, increased attention is being given to the use of biological agents for controlling the vectors of human disease. biological control may encompass the use of predators, pathogens, parasites, pheromones, insect growth regulators, and other factors. of these agents only fish and bacteria have so far been used operationally in mosquito control. since 1988 fish have been employed for controlling aedes larvae in water co ... | 1990 | 1976137 |
| human leukocyte antigens in inhabitants of taiwan. | human leukocyte antigens (hla) were investigated in 200 healthy taiwan inhabitants of taiwanese (46 persons), hakka (36), tai-ya tribe (28) pu-long tribe (30) pai-wan tribe (30) and lu-kai (30) descent. in those of taiwanese and hakka descent, hla-a11 and a2 were the two most frequently seen human leukocyte antigens. hla-a11 was seen in 69.6% in those of taiwanese descent and 61.1% in those of hakka descent. hla-a2 was seen in 50.0% of the taiwanese and 44.4% of the hakka. for the b loci, b40 (t ... | 1990 | 1979593 |
| an autopsy-proved case of aids in taiwan. | the first case of aids positively identified in a non-foreigner in taiwan was a 25-year-old unmarried male who had practiced homosexuality for ten years. the patient began to have abdominal pain accompanied with loose stools and weight loss in june 1985, followed by fever, cough, headache, dizziness, and loss of memory. facial hyperpigmentation and extensive oroesophageal candidiasis were noted. laboratory studies showed severe lymphopenia with a reversed t-helper to t-suppressor ratio, cutaneou ... | 1987 | 3304320 |