| seropositivity to trypanosoma cruzi in blood donors in santa cruz, bolivia. | | 1992 | 1431271 |
| [prospective study of chagas disease in newborn children with placental infection caused by trypanosoma cruzi (santa cruz-bolivia)]. | in order to know the significance of placental infection by t. cruzi 820 newborn infants (nb) weighing less than or equal to 2500 grs were examined both clinically and by the strout method and histopathological sections of the placenta in order to detect congenital infection with chagas' disease. thirty five (4.26%) nb presented a placentary infections by t. cruzi, but having a negative direct parasitological examination in the cord blood, these nb were followed up parasitologically (microhemato ... | 1991 | 1841425 |
| [chagas' disease among blood donors in bolivia]. | a questionnaire survey of blood donors at santa cruz general hospital, bolivia, showed that while there were no seropositive cases of syphilis, hbsag, and hiv, the prevalence of chagas' disease was very high (23%) among the 225 blood donors who responded to this questionnaire. actual cases of chagasic seropositive blood being used for blood transfusion were seen, including the urgent need for a program for chagas' disease in bolivia. from the results of this study, it is recommended that for blo ... | 1994 | 7949272 |
| low probability of transmission of trypanosoma cruzi to humans by domiciliary triatoma sordida in bolivia. | the role of triatoma sordida in the domestic transmission of trypanosoma cruzi was assessed in 7 rural localities in velasco province, department of santa cruz, bolivia. tri. sordida, the only triatomine species identified in these localities, was found inside 58.0% of houses but not in large numbers (3.1 bugs per infested house on average). a total of 220 faecal samples from domiciliary bugs was examined microscopically and by the polymerase chain reaction for the presence of trypanosomes: 21.4 ... | 1997 | 9580115 |
| trypanosoma cruzi genotypes associated with domestic triatoma sordida in bolivia. | triatoma sordida is the second species of triatominae considered of epidemiological significance in bolivia. associated with triatoma infestans in various regions, it is as yet the only triatomine species established in human dwellings in localities of velasco province, department of santa cruz. this domestication is considered as primary. flagellate parasites were detected in 16.2% of domiciliary t. sordida and the kdna-pcr confirmed the presence of trypanosoma cruzi. frequencies of t. cruzi cl ... | 1998 | 9879736 |
| genetic structure of triatoma sordida (hemiptera: reduviidae) domestic populations from bolivia: application on control interventions. | the genetic population of triatoma sordida group 1, a secondary vector of chagas disease in bolivia, was studied by multi-locus enzyme electrophoresis. a total of 253 nymphal and adult specimens collected from seven neighbouring localities in the velasco province, department of santa cruz, were processed. the relatively low genetic variability was confirmed for this species (rate of polymorphism: 0.20). the absence of genetic disequilibrium detected within the seven localities was demonstrated. ... | 1999 | 10348981 |
| detection of kinetoplast dna of trypanosoma cruzi from dried feces of triatomine bugs by pcr. | it is important to clarify the distribution of infected triatomine bugs in the endemic area of chagas' disease for proper control. in the present study, we tried to detect t. cruzi kinetoplast dna by pcr from dried triatomine feces collected from the house wall of an endemic area to assess the distribution of infected bugs more easily. the primers (p35/p36) were chosen to amplify the conserved region within the minirepeats of t. cruzi kinetoplast minicircle dna. the kinetoplast dna of t. cruzi c ... | 2001 | 11438436 |
| the validity of serologic tests for trypanosoma cruzi and the effectiveness of transfusional screening strategies in a hyperendemic region. | this study aims at obtaining unbiased estimates of the sensitivity and specificity of existing screening tests for trypanosoma cruzi and at simulating the effectiveness of alternative screening strategies at different prevalence rates. | 2005 | 15819677 |
| prevention of blood-borne diseases in bolivia, 1993-2002. | this report shows the outcome of a coordinated effort by locals, foreign institutions, and an international agency, from 1996-2002, aimed at preventing transmission of blood-borne diseases in santa cruz, bolivia. from 2001-2002, testing the donor pool for hiv prevented transfusion of 32 infected units and 29 infections. with 100% screening coverage, 196 hepatitis b virus (hbv)-infected units were discarded, and 177 infections of hbv were prevented between 1999 and 2002. incomplete screening for ... | 2008 | 18981527 |
| congenital trypanosoma cruzi transmission in santa cruz, bolivia. | we conducted a study of congenital trypanosoma cruzi infection in santa cruz, bolivia. our objective was to apply new tools to identify weak points in current screening algorithms, and find ways to improve them. | 2009 | 19877966 |
| lineage analysis of circulating trypanosoma cruzi parasites and their association with clinical forms of chagas disease in bolivia. | the causative agent of chagas disease, trypanosoma cruzi, is divided into 6 discrete typing units (dtu): tc i, iia, iib, iic, iid and iie. in order to assess the relative pathogenicities of different dtus, blood samples from three different clinical groups of chronic chagas disease patients (indeterminate, cardiac, megacolon) from bolivia were analyzed for their circulating parasites lineages using minicircle kinetoplast dna polymorphism. | 2010 | 20502516 |
| chagas cardiomyopathy in the context of the chronic disease transition. | patients with chagas disease have migrated to cities, where obesity, hypertension and other cardiac risk factors are common. | 2010 | 20502520 |
| control of rural house infestation by triatoma infestans in the bolivian chaco using a microencapsulated insecticide formulation. | triatoma infestans, the main vector of trypanosoma cruzi (causative agent of chagas disease) has been successfully eliminated over much of its original geographic distribution over the southern cone countries of south america. however, populations of the species are still infesting houses of rural communities of the gran chaco region of argentina and bolivia. this study reports for the first time a large-scale effect of a vector control intervention using a microencapsulated formulation of organ ... | 2015 | 25928071 |
| biomarkers in trypanosoma cruzi-infected and uninfected individuals with varying severity of cardiomyopathy in santa cruz, bolivia. | twenty to thirty percent of persons with trypanosoma cruzi infection eventually develop cardiomyopathy. if an early indicator were to be identified and validated in longitudinal studies, this could enable treatment to be prioritized for those at highest risk. we evaluated cardiac and extracellular matrix remodeling markers across cardiac stages in t. cruzi infected (tc+) and uninfected (tc-) individuals. | 2014 | 25275382 |
| field evaluation of the inbios chagas detect plus rapid test in serum and whole-blood specimens in bolivia. | trypanosoma cruzi causes chagas disease, which affects an estimated 7 million to 8 million people. chagas disease is endemic throughout latin america, with the highest prevalence in bolivia. conventional diagnosis requires a well-equipped laboratory with experienced personnel. we evaluated the chagas detect plus (cdp) (inbios, seattle, wa), a rapid immunochromatographic assay for igg antibodies to t. cruzi. cdp performance was compared to infection status based on results obtained by indirect he ... | 2014 | 25274804 |
| regional variation in the correlation of antibody and t-cell responses to trypanosoma cruzi. | chagas disease, caused by the protozoan parasite trypanosoma cruzi, is a major cause of morbidity and mortality in central and south america. geographic variations in the sensitivity of serologic diagnostic assays to t. cruzi may reflect differences in t. cruzi exposure. we measured parasite-specific t-cell responses among seropositive individuals in two populations from south america with widely varying antibody titers against t. cruzi. antibody titers among seropositive individuals were signif ... | 2014 | 24710614 |
| prevalence of chagas disease in pregnant women and incidence of congenital transmission in santa cruz de la sierra, bolivia. | congenital transmission of chagas disease stand out as a major public health problem since the vector control was performed in all endemic areas and has shown its effectiveness. an epidemiological study was performed in three maternity hospitals of the city of santa cruz de la sierra, bolivia from 2006 to 2008. the serological screening for trypanosoma cruzi infection was carried out in 15,767 pregnant women. chagas infection was detected in 3725 women (23.6%), who gave birth to 125 newborns inf ... | 2012 | 22772023 |
| "i cannot be worried": living with chagas disease in tropical bolivia. | chagas disease (cd) profoundly affects the social and emotional dimensions of patients' lives, and disproportionately impacts poor, marginalized populations in latin america. biomedical treatment for cd fails to reach up to 99% of the people affected, and in any case seldom addresses the emotional health or socioeconomic conditions of patients. this study examines patient strategies for coping with cd in the department of santa cruz, bolivia. | 2017 | 28099488 |
| susceptibility and resistance to deltamethrin of wild and domestic populations of triatoma infestans (reduviidae: triatominae) in bolivia: new discoveries. | bolivia is a high-endemic country for chagas disease, for which the principal vector is triatoma infestans (triatominae). this is a mainly domestic species that is also found in the wild environment. recently, an increasing number of studies have shown the importance of triatominae resistance to insecticides, especially in bolivia. data regarding the susceptibility/resistance of wild and domestic populations of t. infestans to deltamethrin are presented. for the first time, domestic populations ... | 2012 | 23295756 |
| [congenital chagas in bolivia: comparative study of the effectiveness and cost of diagnostic methods]. | eight hundred and twenty newborn babies with a mean weight of < or = 2500g from the maternity hospital p boland in santa cruz- bolivia were examined in 1988-1989 by different methods to diagnose chagas disease, (placental pathology, serology, parasitologically and clinically) to determine the efficiency and cost of these methods. the histopathological exam detected 87 cases of placenta infection. out of this total 43 (49%) newborns were positive on the parasitological exam of the chord blood. th ... | 2007 | 7724866 |
| women and congenital chagas' disease in santa cruz, bolivia: epidemiological and sociocultural aspects. | a total of 910 mothers attending the percy boland maternity institute in santa cruz were investigated. of these mothers, 9.5% transmitted chagas' disease to their children. it was observed that the frequency of congenital transmission in the city was influenced by certain socio-cultural factors relating to the mother, such as increased fertility, early age of motherhood and blood transfusions, and also by the movement of migrants from other endemic regions of bolivia and from rural areas in the ... | 1993 | 8211262 |
| [a study of 39 cases of acute chagas' disease in santa cruz, bolivia (author's transl)]. | | 2013 | 121538 |