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origin and implications of bovine spongiform encephalopathy.all spongiform encephalopathies in animals, including humans, are slow developing infectious diseases. the current working theory links the origin of bovine spongiform encephalopathy (bse) to the feeding of cattle with meat and bone meal prepared from scrapie-infected sheep remains. recycling of cattle meat and bones (mbm) essentially resulted in the selection of a single strain from the "wild type", a mixture of 20 strains. the bse agent is easily transmitted through ingestion, with some eviden ...19968618936
lingering doubts about spongiform encephalopathy and creutzfeldt-jakob disease.bovine spongiform encephalopathy (bse) is an infectious disease and has been transmitted orally to many other animals, including humans. there is clear evidence of maternal transmission, although disagreement on the source of the bse agent remains. the current theories link the origin of bse to common scrapie in sheep. twenty different strains of the scrapie agent have been isolated from sheep. a search of the literature indicates two distinct clinical syndromes in sheep, both of which have been ...200111444100
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