| epidemiological observations on spongiform encephalopathies in captive wild animals in the british isles. | since 1986, scrapie-like spongiform encephalopathy has been diagnosed in 19 captive wild animals of eight species at or from eight zoological collections in the british isles. the affected animals have comprised members of the family bovidae: one nyala (tragelaphus angasi), four eland (taurotragus oryx), and six greater kudu (tragelaphus strepsiceros), one gemsbok (oryx gazella), one arabian oryx (oryx leucoryx), and one scimitar-horned oryx (oryx dammah), and members of the family felidae: four ... | 1994 | 7817514 |
| similar signature of the prion protein in natural sheep scrapie and bovine spongiform encephalopathy-linked diseases. | it has been suggested that specific molecular features could characterize the protease-resistant prion protein (prp res) detected in animal species as well as in humans infected by the infectious agent strain that causes bovine spongiform encephalopathy (bse). studies of glycoform patterns in such diseases in french cattle and cheetahs, as well as in mice infected by isolates from both species, revealed this characteristic molecular signature. similar studies of 42 french isolates of natural scr ... | 1999 | 10523578 |
| first case of feline spongiform encephalopathy in a captive cheetah born in france: prp(sc) analysis in various tissues revealed unexpected targeting of kidney and adrenal gland. | feline spongiform encephalopathy (fse), affecting domestic and captive feline species, is a prion disease considered to be related to bovine spongiform encephalopathy. here we report an immunohistological analysis of the first fse-affected cheetah born in france. the duration of clinical signs, of which ataxia was the main one, was about 8 weeks. the distribution of abnormal prion protein (prp(sc)) was studied by immunohistochemistry within 27 different tissues. different antibodies were used to ... | 2003 | 12783238 |
| pet-blot analysis contributes to bse strain recognition in c57bl/6 mice. | identification of the strain of agent responsible for bovine spongiform encephalopathy (bse) can be made histologically through the analysis of both distribution and intensity of brain vacuolar lesions after bse transmission to mouse. another useful way to distinguish the bse agent from other prion strains is the study of the distribution of the abnormal prion protein (prp(res)). for that purpose, paraffin-embedded tissue blot (pet-blot) method was applied on brains from c57bl/6 mice infected wi ... | 2006 | 16735593 |
| possible case of maternal transmission of feline spongiform encephalopathy in a captive cheetah. | feline spongiform encephalopathy (fse) is considered to be related to bovine spongiform encephalopathy (bse) and has been reported in domestic cats as well as in captive wild cats including cheetahs, first in the united kingdom (uk) and then in other european countries. in france, several cases were described in cheetahs either imported from uk or born in france. here we report details of two other fse cases in captive cheetah including a 2(nd) case of fse in a cheetah born in france, most likel ... | 2009 | 19738899 |