Publications

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transmission, reservoir hosts and control of zoonotic visceral leishmaniasis.zoonotic visceral leishmaniasis (zvl) caused by leishmania infantum is an important disease of humans and dogs. here we review aspects of the transmission and control of zvl. whilst there is clear evidence that zvl is maintained by sandfly transmission, transmission may also occur by non-sandfly routes, such as congenital and sexual transmission. dogs are the only confirmed primary reservoir of infection. meta-analysis of dog studies confirms that infectiousness is higher in symptomatic infectio ...200919835643
[leishmania (leishmania) infantum chagasi in wild canids kept in captivity in the state of mato grosso].visceral leishmaniasis is a zoonosis that affects many mammals, and domestic canids are the main reservoirs in urban environments. this note describes infection by leishmania (leishmania) infantum chagasi among wild canids kept in captivity in the state of mato grosso, brazil.201020563507
low infectiousness of a wildlife host of leishmania infantum: the crab-eating fox is not important for transmission.the epidemiological role of the crab-eating fox cerdocyon thous in the transmission of leishmania infantum is assessed in a longitudinal study in amazon brazil. a total of 37 wild-caught foxes were immunologically and clinically monitored, and 26 foxes exposed to laboratory colonies of the sandfly vector lutzomyia longipalpis, over a 15-month period. in total 78% (29/37) of foxes were seropositive for anti-leishmania igg on at least 1 occasion, and 38% (8/37) had infections confirmed by pcr and/ ...200212458824
visceral leishmaniasis in a captive crab-eating fox cerdocyon thous.visceral leishmaniasis (vl) is a zoonotic disease with worldwide distribution. the crab-eating fox (cerdocyon thous) is considered a wild reservoir of many zoonotical diseases, particularly vl. this study reported the presence of leishmania infantum amastigotes in different organs of one captive c. thous found dead in a zoo. this animal was positive by the indirect fluorescence antibody test and had many clinical signs of vl. intracellular amastigote forms of l. infantum were seen in neutrophils ...201122204055
occurrence of lutzomyia longipalpis lutz & neiva 1912 and cerdocyon thous linnaeus 1977, in a visceral leishmaniasis endemic area in brazil.cerdocyon thous presents a wide geographic distribution in brazil and its role as a possible leishmania infantum reservoir in a visceral leishmaniasis (vl) transmission cycle regardless of dogs (canis familiaris) has been discussed. from this perspective, this work describes the occurrence and use of the habitat by cerdocyon thous in a lutzomyia longipalpis occurrence area teresina (piaui - brazil), vl endemic region. three specimens of c. thous were monitored with the use of radio telemetry and ...201728712973
in vitro infection by leishmania infantum in the peripheral blood mononuclear cell-derived macrophages from crab-eating foxes (cerdocyon thous).wild canids are natural reservoirs of visceral leishmaniais (vl). in brazil, only the crab-eating fox (cerdocyon thous) is a natural reservoir of this zoonotic disease, but there is still a lack of understanding regarding the sylvatic transmission of the leishmania infantum infection. this is the first study on the isolation, cultivation and infection with l. infantum in the peripheral blood mononuclear cell-derived macrophages from crab-eating foxes. it is also the first to compare macrophages ...201526194430
molecular and serological detection of leishmania spp. in captive wild animals from ilha solteira, sp, brazil.leishmaniasis is a zoonotic disease that affects 12 million people worldwide. several mammalian species can serve as a reservoir for this disease. dogs are the main reservoir for visceral leishmaniasis in urban areas, which has become a serious public health concern in brazil. the aim of this study was to evaluate the presence of leishmania spp. in captive wild animals from ilha solteira, são paulo, brazil. blood and various tissues samples were collected from animals of five different species: ...201121961752
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