| threat of foreign arthropod-borne pathogens to livestock in the united states. | there are many exotic animal pathogens throughout the world that, if introduced into the united states. could have a significant detrimental impact on the health of livestock, agricultural economy, the environment, and public health. many of these pathogens are arthropod-borne and potential vectors are readily available in the united states. a number of these arthropod-borne pathogens are discussed here as examples that illustrate the potential risk and the consequences of inadvertent introducti ... | 2002 | 12061432 |
| development of fluorogenic probe-based pcr assays for the detection and quantification of bovine piroplasmids. | this paper reports two new quantitative pcr (qpcr) assays, developed in an attempt to improve the detection of bovine piroplasmids. the first of these techniques is a duplex taqman assay for the simultaneous diagnosis of babesia bovis and b. bigemina. this technique is ideal for use in south america where bovids harbour no theilerids. the second technique, which is suitable for the diagnosis of both babesiosis and theileriosis worldwide, involves fluorescence resonance energy transfer (fret) pro ... | 2009 | 19376655 |
| evaluation of the in vitro growth-inhibitory effect of epoxomicin on babesia parasites. | epoxomicin potently and irreversibly inhibits the catalytic activity of proteasomal subunits. treatment of proliferating cells with epoxomicin results in cell death through accumulation of ubiquinated proteins. thus, epoxomicin has been proposed as a potential anti-cancer drug. in the present study, the inhibitory effects of epoxomicin on the in vitro growth of bovine and equine babesia parasites were evaluated. the inhibitory effect of epoxomicin on the in vivo growth of babesia microti was als ... | 2010 | 19896277 |
| growth inhibitory effect of triclosan on equine and bovine babesia parasites. | we evaluated the growth inhibitory effect of triclosan, which has recently been reported to inhibit the growth of plasmodium species and toxoplasma gondii, on bovine and equine babesia parasites in in vitro cultures the growth of babesia bovis and b. bigemina was significantly inhibited in the presence of 100 microg/ml of triclosan, while b. caballi and b. equi were susceptible to as low as 50 microg/ml. babesia bigemina and b. caballi were completely cleared as early as on the first and second ... | 2003 | 12685641 |
| cellular localization of babesia bovis merozoite rhoptry-associated protein 1 and its erythrocyte-binding activity. | the cellular localization of babesia bovis rhoptry-associated protein 1 (rap-1) and its erythrocyte-binding affinity were examined with anti-rap-1 antibodies. in an indirect immunofluorescent antibody test, rap-1 was detectable in all developmental stages of merozoites and in extracellular merozoites. in the early stage of merozoite development, rap-1 appears as a dense accumulation, which later thins out and blankets the host cell cytoplasm, but retains a denser mass around newly formed parasit ... | 2002 | 12228313 |