Publications

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sporogonic development of hepatozoon americanum (apicomplexa) in its definitive host, amblyomma maculatum (acarina).light microscopic observations of the sporogonic development of hepatozoon americanum are described in its acarine host, amblyomma maculatum. laboratory-reared nymphal ticks were fed on 2 dogs infected with h. americanum. nymphal ticks were sampled daily, starting 3 days after being placed on a parasitemic dog, until 18 days after infestation (pi), and then every 3 or 4 days until replete nymphs molted. ticks were examined as unstained wet mounts and hematoxylin-eosin-stained paraffin sections. ...199910647032
skeletal lesions of canine hepatozoonosis caused by hepatozoon americanum.canine hepatozoonosis, caused by hepatozoon americanum, is an emerging tick-borne disease of dogs in north america. in addition to the skeletal and cardiac myositis that are prominent features of the disease, there is disseminated periosteal bone proliferation in most dogs that manifest clinical disease. each of six experimentally infected animals (four dogs and two coyotes) and seven of eight naturally infected dogs had gross or histopathologic osteoproliferative lesions. experimental animals w ...200010810986
larval gulf coast ticks (amblyomma maculatum) [acari: ixodidae] as host for hepatozoon americanum [apicomplexa: adeleorina].laboratory-reared larval gulf coast ticks (gcts) (amblyomma maculatum) were exposed experimentally and found to acquire hepatozoon americanum infection while feeding on parasitemic dogs. these ticks supported gamogonic and sporogonic development of the apicomplexan, and oocysts from newly molted nymphs were infectious for a dog. other nymphs from this cohort that were allowed to feed on a blood-parasite naive sheep molted normally; the resulting adult ticks contained oocysts that were infectious ...200211750999
alternate pathway of infection with hepatozoon americanum and the epidemiologic importance of predation.the range of american canine hepatozoonosis (ach) is expanding from the southern usa northward. transmission of hepatozoon americanum occurs by ingestion of infected gulf coast ticks, amblyomma maculatum. the source of the protozoan for the tick remains undetermined; infected dogs are unusual hosts for the tick.200919709355
treatment of hepatozoon americanum infection: review of the literature and experimental evaluation of efficacy.there is no labeled treatment for dogs with american canine hepatozoonosis (ach), but the drug therapies discussed in this article, although not rapidly curative, may be successful in alleviating acute clinical signs, prolonging life, reducing the number of clinical relapses, and enhancing quality of life. this article also describes a pilot trial conducted to assess the efficacy of a novel treatment approach with ponazuril as a stand-alone parasiticide administered for 4 weeks without follow-up ...201021308664
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