| role of helicobacter felis in chronic canine gastritis. | five gnotobiotic beagle dogs were orally inoculated with a pure culture of helicobacter felis. the remaining two littermates served as contact controls. thirty days after infection, all animals were euthanatized and specimens were collected for evaluation. in infected dogs, h. felis was recovered from all areas of the stomach. colonization was heaviest in the fundus and antrum. h. felis was not cultured from any segment of the gastrointestinal tract distal to the duodenum. two weeks after infect ... | 1992 | 1448894 |
| animal models and vaccine development. | following the demonstration of helicobacter pylori as a major gastroduodenal pathogen there was a need to develop animal models in order to investigate mechanisms of pathogenesis and to be able to test new treatment strategies. helicobacter pylori will only colonize a limited number of hosts including non-human primates, germ-free or barrier raised piglets, germ-free dogs and recently laboratory raised cats. although these models have proved useful there is a need for more convenient small anima ... | 1995 | 8563056 |
| prevalence and varieties of helicobacter species in dogs from random sources and pet dogs: animal and public health implications. | gastric bacteria of a variety of ultrastructural morphologies have been identified in or isolated from domestic carnivores, but their prevalence in different populations of animals and their clinical significance are still unknown. the purposes of this study were (i) to evaluate the prevalence and morphologic types of gastric bacterial in three different populations of dogs; (ii) to determine which of the organisms were culturable, and if the cultured organisms were morphologically similar to th ... | 1996 | 8940465 |
| helicobacter salomonis sp. nov., a canine gastric helicobacter sp. related to helicobacter felis and helicobacter bizzozeronii. | during a study of the prevalence and distribution of gastric helicobacters in domestic pets, a novel group of helicobacter-like organisms were identified. these "helicobacter group 2" strains were initially distinguished from the species helicobacter felis and helicobacter bizzozeronii by their cellular morphology and the type of motility exhibited. bacterial cells were only slightly spiral, 5 to 7 microns long, and 0.8 to 1.2 microns wide and showed an unusual slow wavelike motion. each cell ha ... | 1997 | 9336895 |
| occurrence and characterization of gastric helicobacter spp. in naturally infected dogs. | helicobacter-like organisms are frequently observed in the stomach of dogs but the relationship between these microorganisms and gastric pathology has not been clearly established. different species of helicobacters are known to be present in the canine stomach but their specific prevalence in naturally infected dogs is unknown. the aims of this study were to isolate and characterize helicobacters in canine gastric biopsies, to compare the commonly used tests for the identification of helicobact ... | 1999 | 10596807 |
| evaluation of a group-specific 16s ribosomal dna-based pcr for detection of helicobacter bizzozeronii, helicobacter felis, and helicobacter salomonis in fresh and paraffin-embedded gastric biopsy specimens. | a new specific and sensitive 16s ribosomal dna-based pcr assay was developed. the assay targets a 78-bp dna fragment unique to helicobacter bizzozeronii, helicobacter felis, and helicobacter salomonis and can be used with freshly frozen and formalin-fixed paraffin-embedded gastric biopsy specimens. | 2001 | 11230459 |
| gastric helicobacters in cats. | the types of helicobacter which are found in the stomachs of carnivorous pets, especially cats, have been traditionally referred to as 'gastric helicobacter-like organisms' (ghlos). these are microaerophilic, gram-negative, spiral bacteria with multiple terminal flagellae and are endowed with high-level urease activity which allows them to survive in an acidic environment. certain species have one or more periplasmic fibrils. the two ghlos most commonly found in cats are helicobacter felis and a ... | 2000 | 11716588 |
| helicobacter felis and helicobacter bizzozeronii induce gastric parietal cell loss in mongolian gerbils. | non-pylori helicobacter infections are associated with gastritis, gastric ulcers and malt lymphomas in man. approximately 50% of these are caused by helicobacters commonly found in dogs and cats, including helicobacter felis, helicobacter bizzozeronii and h. salomonis. in contrast to helicobacter pylori, the virulence mechanisms of these species are unknown. in this study the virulence of h. felis, h. bizzozeronii and h. salomonis was investigated in mongolian gerbils. female spf gerbils were in ... | 2006 | 16311055 |
| isolation and characterization of helicobacter suis sp. nov. from pig stomachs. | a new cultivation method was successfully applied for the in vitro isolation of a hitherto uncultured spiral helicobacter species associated with ulceration of the non-glandular stomach and gastritis in pigs and formerly described as 'candidatus helicobacter suis'. three isolates, hs1(t), hs2 and hs3, were subcultured from the stomach mucosa of three pigs after slaughter and were analysed using a polyphasic taxonomic approach. the novel isolates grew on biphasic culture plates or very moist agar ... | 2008 | 18523177 |
| crystal structure and functional insight of hp0420-homolog from helicobacter felis. | helicobacter pylori infect more than half of the world's population and are considered a cause of peptic ulcer disease and gastric cancer. recently, hypothetical gene hp0421 was identified in h. pylori as a cholesterol alpha-glucosyltransferase, which is required to synthesize cholesteryl glucosides, essential cell wall components of the bacteria. in the same gene-cluster, hp0420 was co-identified, whose function remains unknown. here we report the crystal structure of hp0420-homolog of h. felis ... | 2010 | 20302842 |
| the other helicobacters. | the last year has seen an interesting and important collection of evidence presented in the field of the "other" than helicobacter pylori helicobacters. associations with adult ulcerative colitis and biliary/hepatic disease have been described. new insights into the immune response and subsequent pathogenesis associated with infection have also been published. genomic advances include description of new and unique species and the complete genome description for both helicobacter felis and helico ... | 2011 | 21896089 |