| suboptimal splice sites of equine infectious anaemia virus control rev responsiveness. | the rev protein of equine infectious anaemia virus (eiav) was shown previously to stimulate the expression of a heterologous cat reporter gene when the 3' half of the eiav genome was present downstream in cis. however, computer analysis could not reveal the existence of a stable rna secondary structure that could be analogous to the rev-responsive element of other lentiviruses. in the present study, the inhibitory rna element designated the cis-acting repressing sequence (crs) has been localized ... | 2000 | 10769069 |
| canine cyclin t1 rescues equine infectious anemia virus tat trans-activation in human cells. | human immunodeficiency virus-1 tat protein and human cyclin t1 mediate transcriptional activation by enhancing the elongation efficiency of rna polymerase ii. activation of transcription of the related equine infectious anemia virus (eiav) requires a similar protein known as etat, which does not function in human cells. expression of equine cyclin t1 in human cells rescues etat function, suggesting a general mechanism of transcription activation among lentiviruses. here we present the cloning of ... | 2000 | 10683321 |
| spontaneous autoimmune diseases of domestic animals. | | 1974 | 4367527 |
| rapid detection of viral-specific antibodies by enzyme-linked immunosorbent assay (elisa). | the development of three separate rapid elisas for detecting antibodies in host serum to three different viruses is described. these include: 1. a direct antigen assay using enzyme labelled anti-canine ig for detecting antibodies to canine parvovirus, 2. a competitive elisa using a feline infectious peritonitis virus-specific monoclonal antibody labelled with enzyme, and 3. a competitive elisa using an equine infectious anemia virus-specific monoclonal antibody and enzyme labelled antigen, p. 26 ... | 1987 | 2829416 |