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development and sexual maturation of echinococcus granulosus adult worms in the alternative definitive host, mongolian gerbil (meriones unguiculatus).in the present study for the first time an alternative definitive host model has been established for the complete development of echinococcus granulosus in meriones unguiculatus (mongolian gerbils) up to shelled eggs production, as happened in the natural host. animals treated with methylprednisolone acetate were orally inoculated with approximately 3000 protoscoleces and the development of parasites in the small intestine observed up to 46 days post-infection (p.i.). the cestodes survive, stro ...200616324680
[experimental observation on anaphylaxis induced by echinococcus infection in meriones unguiculatus].to observe the anaphylaxis induced by echinococcus granulosus or e. multilocularis (e. g. and e. m.) infection in meriones unguiculatus.200012567730
pharmacokinetics of netobimin and microsomal metabolism of albendazole in infected gerbils with echinococcus granulosus.a comparison of the pharmacokinetic profiles of netobimin (ntb), albendazole sulfoxide (abzso) and albendazole sulfone (abzso2) was performed in gerbils (meriones unguiculatus) with intra-abdominal hydatidosis and in healthy gerbils. the infection was developed after peritoneal inoculation of protoscolices of echinooccus granulosus from sheep. plasma concentrations of ntb, abzso and abzso2 were measured by hplc after oral administration of 50 mg ntb kg(-1). the results showed an incomplete biotr ...200111206105
in vivo inhibition of the regenerative capacity of hydatid material after treatment with netobimin.the effect of netobimin and netobimin plus fenbendazole administration on secondary hydatid disease was studied. secondary hydatid disease in gerbils (meriones unguiculatus) was produced by intraperitoneal inoculation of protoscolices of echinococcus granulosus. the experimental animals received doses of 20 and 50 mg/kg of netobimin or a mixture of netobimin and 1.7 mg/kg of fenbendazole. the results showed that after a single dose of netobimin at the studied concentrations, the cystic material ...19979039691
primary cystic infection with echinococcus granulosus and taenia hydatigena in meriones unguiculatus. 19705421089
the propagation of secondary cysts of echinococcus granulosus in the mongolian jird, meriones unguiculatus. 19705413854
demonstration of a specific echinococcus multilocularis antigen in the supernatant of in vitro maintained protoscolices.serodiagnosis of echinococcosis is still often met with difficulties resulting from unspecific reactions due to crude antigens which contain numerous host-derived proteins. in order to eliminate host protein contamination we produced echinococcus multilocularis antigen by methods of in vitro technique: evaginated protoscolices of echinococcus multilocularis isolated from experimentally infected mongolian gerbils (meriones unguiculatus) were maintained in rpmi 1640 medium. although no serum prote ...19883407363
the development of brood capsules and protoscolices in secondary hydatid cysts of echinococcus granulosus. a histological study.using the mongolian jird (meriones unguiculatus) as a laboratory host for the cystic stage of the british horse strain of echinococcus granulosus, the mode of development of brood capsules and protoscolices was studied histologically. the successive stages in development in secondary hydatid cysts are described and shown to correspond closely with previous observations on primary hydatid cysts. the usefulness of this experimental model for future ultrastructural studies is emphasized.19761016477
immunological response to experimental echnococcosis in meriones unguiculatus.varying doses of protoscolices of echinococcus granulosus were injected intraperitoneally into mongolian jirds, swiss mice, and golden hamsters. after 4 months the animals were killed and the numbers of developing cysts counted. jirds were by far the most susceptible hosts. doses of 500 protoscolices produced 100% infection rates in both weanlings and adults. comparable infection rates in weanling mice required inocula of 5,000 protoscolices, but even at this dose hamsters were refractory to inf ...1976957034
the mongolian gerbil (meriones unguiculatus) as a laboratory host for the cystic stage of echinococcus granulosus of british horse origin. 1976795771
chemotherapy of experimental echinococcus granulosus infection. trials in cf1 mice and jirds (meriones unguiculatus).mice and jirds with experimental secondary hydatidosis (echinococus granulous) were treated at various post-infection periods with eight different drugs; iodinized oil of thymol, ethyl-n-dimethyl ether of thymol fumarate, chloroguanide, rifampin, pentamidine isethionate, amphotericin b, suramin, and methotrexate. in initial experiments with methotrexate, mice treated after 99 days of infection had significantly fewer infections at necropsy than did controls (33% and 100%, respecitively). however ...1975163063
the effect of egg dose, and host age and sex on susceptibility of cf1 albinomice and jirds (meriones unguiculatus) to primary infection by echinococcus granulosus(batsh, 1786). 19751153912
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