| genomic sequence of spodoptera frugiperda ascovirus 1a, an enveloped, double-stranded dna insect virus that manipulates apoptosis for viral reproduction. | ascoviruses (family ascoviridae) are double-stranded dna viruses with circular genomes that attack lepidopterans, where they produce large, enveloped virions, 150 by 400 nm, and cause a chronic, fatal disease with a cytopathology resembling that of apoptosis. after infection, host cell dna is degraded, the nucleus fragments, and the cell then cleaves into large virion-containing vesicles. these vesicles and virions circulate in the hemolymph, where they are acquired by parasitic wasps during ovi ... | 2006 | 16987980 |