| isolation of bovine adenovirus type 4 from cattle in oregon. | four isolates of bovine adenovirus type 4 were recovered from oregon cattle. one isolate was recovered from a 1-week-old calf with pneumoenteritis, and 1 isolate from an 8-month-old bull with fever and respiratory disease. two isolates were recovered as latent viruses in testicular cell cultures. all 4 isolates of the virus were shown to have certain physical, chemical, biologic, and antigenic characteristics similar to previously described strains of bovine adenovirus type 4. of 246 adult beef ... | 1977 | 202178 |
| analysis of the hexon gene sequence of bovine adenovirus type 4 provides further support for a new adenovirus genus (atadenovirus). | the putative hexon gene of bovine adenovirus type 4 (bav-4), encoding 910 amino acid residues, has been identified and sequenced. a characteristic codon usage biased towards the use of at-rich triplets was observed. comparative analysis with other hexon sequences detected a high level of amino acid identity in the regions corresponding to the pedestals of the hexon. substitutions, insertions and deletions were identified mainly in the variable regions forming the loops which are exposed on the o ... | 1998 | 9634088 |
| pathological and in situ hybridisation findings in calves experimentally infected with bovine adenovirus type 4. | three colostrum deprived calves were inoculated intravenously with a strain of bovine adenovirus type 4 (bav-4) isolated from a calf with acute fibrinous enteritis. the calves were monitored clinically and submitted to post mortem examination at 5, 6 and 10 days post inoculation (p. i.) respectively. the 3 animals showed raise in temperature and diarrhoea. acute enteritis was observed in calves submitted to post mortem examination at 5 and 6 days p. i. in these animals viral dna was specifically ... | 1998 | 9618984 |
| adenoviral fibrinous enteritis in calves. | two calves coming from different herds showed at post-mortem examination a fibrinous enteritis with mucosal necrosis particularly in the ileal-colonic tract. histologically, amphophilic intranuclear inclusion bodies were the main feature. they were located in the endothelial cells of the intestine and mesenteric lymph cells. ultramicroscopic examination of the inclusion bodies revealed the presence of an adenovirus. in one case the virus was isolated on cell cultures and further classified as bo ... | 1989 | 2540945 |
| abolition of hcar-dependent cell tropism using fiber knobs of atadenovirus serotypes. | most adenoviral vectors use in gene therapy protocols derive from species c. however, expression of the primary receptor (human coxsackievirus and adenovirus receptor, hcar) for these adv is variable on cancer cells. in vivo targeting of a therapeutic gene to specific cells has then become a major issue in gene therapy. the ad fiber protein largely determines viral tropism through interaction with specific receptors. hereto, we constructed a set of hadv5 vectors carrying chimeric fibers with kno ... | 2004 | 15051380 |
| odocoileus hemionus deer adenovirus is related to the members of atadenovirus genus. | the odocoileus hemionus deer adenovirus (odadv-1) causes systemic and local vasculitis and proves extremely lethal for mule deer. to characterize the virus, part of the genome flanking the fiber gene was cloned and sequenced. the sequence revealed two open-reading frames that mapped to pviii hexon-associated protein precursor and fiber protein of several other adenoviruses. the highest amino acid homology for pviii and fiber was found with the members of the proposed atadenovirus genus: ovine ad ... | 2002 | 12038693 |
| genetic organization and sequence analysis of pviii, fiber and early region 4 of bovine adenovirus type 7. | the dna sequence of 8,810 nucleotides at the right end of bovine adenovirus type 7 (bav7) genome was determined and compared with similar regions of other adenoviruses. this genomic region of bav7 consists of sequences encoding partial 33k, pviii, fiber, putative early region 4 (e4) proteins and other unassigned proteins. however, bav7 e3 region is not present in the expected location between pviii and fiber as bav7 intergenic region between pviii and fiber genes is only 183 nucleotides. the pre ... | 2002 | 12206309 |