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profiling of subgingival plaque biofilm microflora from periodontally healthy subjects and from subjects with periodontitis using quantitative real-time pcr.qualitative and quantitative changes of the subgingival plaque biofilm microflora in periodontal pockets are thought to be associated with the development and progression of periodontitis. the aims of the present study were to quantify the proportions of nine periodontitis-associated bacterial species and four streptococcus species in subgingival plaque, and to evaluate their relationship with periodontitis quantitatively.201020337892
new bacterial species associated with chronic periodontitis.recent investigations of the human subgingival oral flora based on ribosomal 16s cloning and sequencing have shown many of the bacterial species present to be novel species or phylotypes. the purpose of the present investigation was to identify potential periodontal pathogens among these newly identified species and phylotypes. species-specific ribosomal 16s primers for pcr amplification were developed for detection of new species. associations with chronic periodontitis were observed for severa ...200312709498
intraperitoneal immune cell responses to eubacterium saphenum in mice.oral asaccharolytic eubacterium saphenum, which are newly isolated gram-positive rods and one of the predominant microorganisms in human periodontal pockets, were injected intraperitoneally in mice to elucidate their pathogenicity in periodontal diseases. infiltrating immune cells in the peritoneal exudate were quantitated and intracellular t cell (cd4+/cd8+/gammadelta+) production of cytokines il-4 and ifn-gamma which are related to cellular and humoral immunity, respectively, was determined. n ...200111270604
eubacterium saphenum sp. nov., isolated from human periodontal pockets [corrected].a new species, eubacterium saphenum [corrected] sp. nov., established on the basis of the results of dna-dna hybridization, was proposed for strains isolated from human periodontal pockets. differential characteristics are given.19938494741
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