| european bat lyssavirus type 2: human exposure in england. | | 2007 | 17900428 |
| comparative analysis of the full genome sequence of european bat lyssavirus type 1 and type 2 with other lyssaviruses and evidence for a conserved transcription termination and polyadenylation motif in the g-l 3' non-translated region. | we report the first full-length genomic sequences for european bat lyssavirus type-1 (eblv-1) and type-2 (eblv-2). the eblv-1 genomic sequence was derived from a virus isolated from a serotine bat in hamburg, germany, in 1968 and the eblv-2 sequence was derived from a virus isolate from a human case of rabies that occurred in scotland in 2002. a long-distance pcr strategy was used to amplify the open reading frames (orfs), followed by standard and modified race (rapid amplification of cdna ends) ... | 2007 | 17374776 |
| eblv-2 prevalence in the united kingdom as determined by surveillance testing. | five cases of eblv-2 have been detected in the uk since 1996, with all wildlife cases in the daubenton's bat: one on the south coast in sussex in 1996, one in lancashire in 2002, another in 2003, one in surrey in 2004 and a human fatality in angus, scotland, in 2002. as a result of the human case, a seroprevalence study, aimed primarily at the daubenton's bat was conducted in 2003 in scotland and at some sites in england. in scotland, 198 daubenton's, 20 natterer's and 6 pipistrelles were caught ... | 2006 | 16878484 |
| ability of rabies vaccine strains to elicit cross-neutralising antibodies. | two european bat lyssaviruses (eblv-1 and eblv-2) have been identified (n > 750 cases) in european bat species. in addition, eblvs have been detected as "spillover" cases in three humans, one stone marten and four sheep. a further concern is the interaction of companion animals with infected bats and the possibility of subsequent lyssavirus infection. cat-bat interactions represent approximately 32 % (n = 398) of passive lyssavirus surveillance submissions at the veterinary laboratories agency ( ... | 2006 | 16878476 |
| european bat lyssaviruses: an emerging zoonosis. | in europe, two bat lyssaviruses referred to as european bat lyssaviruses (eblvs) types 1 and 2 (genotypes 5 and 6 respectively) which are closely related to classical rabies virus are responsible for an emerging zoonosis. eblvs are host restricted to bats, and have been known to infect not only their primary hosts but also in rare circumstances, induce spillover infections to terrestrial mammals including domestic livestock, wildlife and man. although spillover infections have occurred, there ha ... | 2003 | 14959767 |
| investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison. | cross-neutralization between rabies virus (rabv) and two european bat lyssaviruses (eblv-1 and -2) was analysed using lentiviral pseudotypes as antigen vectors. glycoprotein (g-protein) cdna from rabv challenge virus standard-11 (cvs-11) and eblv-1 and -2 were cloned and co-expressed with human immunodeficiency virus (hiv) or murine leukemia virus (mlv) gag-pol and packageable green fluorescent protein (gfp) or luciferase reporter genes in human cells. the harvested lentiviral (hiv) vector infec ... | 2008 | 18753230 |
| first encounter of european bat lyssavirus type 2 (eblv-2) in a bat in finland. | in finland, rabies in bats was suspected for the first time in 1985 when a bat researcher, who had multiple bat bites, died in helsinki. the virus isolated from the researcher proved to be antigenically related to rabies viruses previously detected in german bats. later, the virus was typed as eblv-2b. despite an epidemiological study in bats 1986 and subsequent rabies surveillance, rabies in bats was not detected in finland until the first case in a daubenton's bat (myotis daubentonii) was conf ... | 2010 | 20196902 |
| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |