[rabies virus in naturally infected bats in the state of são paulo, southeastern brazil].to identify the species of bats involved in maintaining the rabies cycle; to investigate the distribution of the rabies virus in the tissues and organs of bats and the time taken for mortality among inoculated mice.200717515992
[rabies virus in nyctinomops laticaudatus bats in the city of rio de janeiro: isolation, titration and epidemiology].the first case report of rabies in bats of the species nyctinomops laticaudatus, in the city of rio de janeiro city, is presented. virus isolation and titration were performed in different tissues, and high titers were found in the brain and salivary glands. rabies occurrence in such an infrequent species in this state suggests that the disease may be more prevalent than it appears to be.200717876476
pathogenicity of different rabies virus isolates and protection test in vaccinated mice.this study was aimed to evaluate and compare the pathogenicity of rabies virus isolated from bats and dogs, and to verify the efficacy of a commercial rabies vaccine against these isolates. for evaluation of pathogenicity, mice were inoculated by the intramuscular route (im) with 500micld₅₀/0.03 ml of the viruses. the cross-protection test was performed by vaccinating groups of mice by the subcutaneous route and challenged through the intracerebral (ic) route. isolates were fully pathogenic when ...201021049225
rabies diagnosis and serology in bats from the state of são paulo, brazil.bats are one of the most important reservoirs and vectors of the rabies virus in the world.201121468481
monoclonal antibodies for characterization of rabies virus isolated from non-hematophagous bats in brazil, various isolates of rabies virus (rabv) show antigenic profiles distinct from those established by the reduced panel of eight monoclonal antibodies (mabs) determined by the centers for disease control and prevention (cdc), utilized for the antigenic characterization of rabv in the americas. the objective of this study was to produce mabs from rabv isolates from insectivorous bats with an antigenic profile incompatible with the pre-established one.201526623633
host and viral traits predict zoonotic spillover from mammals.the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ...201728636590
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