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canine distemper virus infection in serengeti spotted hyenas.clinical signs suggestive of canine distemper virus (cdv) infection were observed among a group of spotted hyenas (crocuta crocuta) in the serengeti, tanzania. virus antigen was detected immunohistologically in a brain sample from a diseased cub. the presence of virus rna could be demonstrated in this brain as well as in intestine and lymph node of the animal by rt-pcr. sequence comparison of brain-derived amplicons showed that the virus was related to recent cdv field isolates. the closest homo ...19968861651
serosurvey for selected viral pathogens among sympatric species of the african large predator guild in northern botswana.the recent increase in the creation of transboundary protected areas and wildlife corridors between them lends importance to information on pathogen prevalence and transmission among wildlife species that will become connected. one such initiative is the kavango zambezi transfrontier conservation area of which botswana's okavango delta constitutes a major contribution for wildlife and ecosystems. between 2008 and 2011, we collected serum samples from 14 lions ( panthera leo ), four leopards ( pa ...201727763827
cross-species transmission of canine distemper virus-an update.canine distemper virus (cdv) is a pantropic morbillivirus with a worldwide distribution, which causes fatal disease in dogs. affected animals develop dyspnea, diarrhea, neurological signs and profound immunosuppression. systemic cdv infection, resembling distemper in domestic dogs, can be found also in wild canids (e.g. wolves, foxes), procyonids (e.g. raccoons, kinkajous), ailurids (e.g. red pandas), ursids (e.g. black bears, giant pandas), mustelids (e.g. ferrets, minks), viverrids (e.g. civet ...201528616465
rabies virus and canine distemper virus in wild and domestic carnivores in northern kenya: are domestic dogs the reservoir?rabies virus (rv) and canine distemper virus (cdv) can cause significant mortality in wild carnivore populations, and rv threatens human lives. we investigated serological patterns of exposure to cdv and rv in domestic dogs (canis familiaris), african wild dogs (lycaon pictus), black-backed jackals (canis mesomelas), spotted hyenas (crocuta crocuta), striped hyenas (hyaena hyaena) and african lions (panthera leo), over a 10-year period, in a kenyan rangeland to assess the role domestic dogs may ...201223459924
antibodies to canine and feline viruses in spotted hyenas (crocuta crocuta) in the masai mara national reserve.spotted hyenas (crocuta crocuta) are abundant predators in the serengeti ecosystem and interact with other species of wild carnivores and domestic animals in ways that could encourage disease transmission. hyenas also have a unique hierarchical social system that might affect the flow of pathogens. antibodies to canine distemper virus (cdv), feline immunodeficiency virus (fiv), feline panleukopenia virus/canine parvovirus (fplv/cpv), feline coronavirus/ feline infectious peritonitis virus (fecv/ ...200415137483
characterization of toll-like receptors 1-10 in spotted hyenas.previous research has shown that spotted hyenas (crocuta crocuta) regularly survive exposure to deadly pathogens such as rabies, canine distemper virus, and anthrax, suggesting that they have robust immune defenses. toll-like receptors (tlrs) recognize conserved molecular patterns and initiate a wide range of innate and adaptive immune responses. tlr genes are evolutionarily conserved, and assessing tlr expression in various tissues can provide insight into overall immunological organization and ...201424488231
genetic characterization of canine distemper virus in serengeti carnivores.the lion (panthera leo) population in the serengeti ecosystem was recently afflicted by a fatal epidemic involving neurological disease, encephalitis and pneumonia. the cause was identified as canine distemper virus (cdv). several other species in the serengeti were also affected. this report presents cdv h and p gene sequences isolated from serengeti lions (panthera leo), spotted hyenas (crocuta crocuta), bat-eared fox (otocyon megalotis) and domestic dog (canis familiaris). sequence analyses d ...19989839878
rabies, canine distemper, and canine parvovirus exposure in large carnivore communities from two zambian ecosystems.disease transmission within and among wild and domestic carnivores can have significant impacts on populations, particularly for threatened and endangered species. we used serology to evaluate potential exposure to rabies virus, canine distemper virus (cdv), and canine parvovirus (cpv) for populations of african lions (panthera leo), african wild dogs (lycaon pictus), and spotted hyenas (crocuta crocuta) in zambia's south luangwa national park (slnp) and liuwa plain national park (lpnp) as well ...201323805791
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