| development and assessment of human adenovirus type 11 as a gene transfer vector. | adenovirus vectors based on human serotype 5 (ad5) have successfully been used as gene transfer vectors in many gene therapy-based approaches to treat disease. despite their widespread application, many potential therapeutic applications are limited by the widespread prevalence of vector-neutralizing antibodies within the human population and the inability of ad5-based vectors to transduce important therapeutic target cell types. in an attempt to circumvent these problems, we have developed ad v ... | 2005 | 15795294 |