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[on echinococcus multilocularis in southern germany ii. development of the larval stages and histopathological reactions in common vole, microtus arvalis (author's transl)]. 1977601851
[intermediate hosts of echinococcus multilocularis in northeastern france. description of lesions found in 3 naturally infested rodent species].the authors describe lesions of echinococcus multilocularis larvae found in one of 476 clethrionomys glareolus and one of 16 arvicola terrestris examined from lorraine and in four microtus arvalis from jura. the receptivity of each of these host-species is discussed.19863524402
[increased risk of infection by echinococcus multilocularis for people in the endemic "schwaebische alb" region?].the infestation by the larva of echinococcus multilocularis, also known as alveolar echinococcosis, is the most dangerous parasitic disease of man in middle europe. this is due to the location in the liver but still more so because of the proliferative and infiltrating growth of the larval tissue. the basic infective cycle of the parasite is a zoonosis between foxes as final hosts and small rodents such as common voles as intermediate hosts. man can be a false intermediate host and thus a carrie ...19853901604
[towards a strategy for the epidemiological study of alveolar echinococcosis. apropos of cases of infestation seen in microtus arvalis p. in the doubs (france)].the aim of the authors is to give some precisions about the relationship between the cycle of echinococcus multilocularis and the dynamics of the different potential hosts (rodents and carnivorous) existing on the area under study (sept-fontaines, doubs, france), by analysing the results of rodents trapping operation (mainly on microtus arvalis) some of it are infested by the parasite. for this purpose they include the parasite in a prey-predator system and show how the behavioural pattern of th ...19853909889
[detection of the larva of taenia multilocularis in 2 voles (microtus arvalis and clethrionomys glareolus) in a focus of alveolar echinococcosis in the massif central (france)].small wild rodents were collected and examined during 1983-1984 to investigate parasite-host relationships of echinococcus multilocularis in one habitat suitable for red foxes of auvergne (france). the natural infestation of the liver of two different voles, microtus arvalis and clethrionomys glareolus, by the larval stage of the cestode is recorded for the first time. in the both cases, the larvae were fully developed and numerous protoscolices were present with some calcareous corpuscules; the ...19846440675
a model for the control of echinococcus multilocularis in france.in some areas of france the prevalence of echinococcus multilocularis in foxes is as high as 50%, whereas less than one in a thousand voles (principally microtus arvalis) are infected. in these regions the control of rabies in foxes is achieved by using helicopters to spread bait containing oral vaccine in capsules. a mathematical model has been constructed in an attempt to determine if the addition of praziquantel to bait would be effective in eradicating e. multilocularis, or at least achieve ...19957732652
influence of environmental factors on the infectivity of echinococcus multilocularis eggs.the sensitivity of eggs of echinococcus multilocularis to environmental and controlled laboratory conditions was tested. egg material was exposed and the infectivity was subsequently monitored by in vitro activation and by oral infection of the natural host, microtus arvalis. to study the impact of environmental conditions in an endemic area of south-western germany, eggs were sealed into bags of nylon mesh and exposed to the natural climate during various seasons. the maximal survival time of e ...19957845716
is high prevalence of echinococcus multilocularis in wild and domestic animals associated with disease incidence in humans?we investigated a focus of highly endemic echinococcus multilocularis infection to assess persistence of high endemicity in rural rodents, explore potential for parasite transmission to domestic carnivores, and assess (serologically) putative exposure versus infection frequency in inhabitants of the region. from spring 1993 to spring 1998, the prevalence of e. multilocularis in rodents was 9% to 39% for arvicola terrestris and 10% to 21% for microtus arvalis. from june 1996 to october 1997, 6 (7 ...200111384517
echinococcus multilocularis: secondary poisoning of fox population during a vole outbreak reduces environmental contamination in a high endemicity area.this paper describes the role of fox population level on echinococcus multilocularis infection in foxes in a highly endemic area in eastern france. fox population level was monitored by spotlight survey at le souillot from 1989 to 2000, and from 1992 to 2000 at chemin, a control site located in a low endemic area. the infection level of the fox population was estimated at le souillot from winter 1995 to winter 1999 using a coproantigen elisa performed on faeces collected in the field. population ...200312906878
milbemycin oxime in a new formulation, combined with praziquantel, does not reduce the efficacy of praziquantel against echinococcus multilocularis in cats.twenty european domestic cats were each infected with 15,000 protoscoleces of echinococcus multilocularis extracted from metacestodes grown in experimentally infected common voles (microtus arvalis). sixteen days after infection, ten cats were treated with a broad-spectrum anthelmintic and acaricide comprising praziquantel and milbemycin oxime. five days later treated and untreated cats were euthanized and the intestine examined for e. multilocularis. five of ten untreated cats were infected wit ...200314627455
processes leading to a spatial aggregation of echinococcus multilocularis in its natural intermediate host microtus arvalis.the small fox tapeworm (echinococcus multilocularis) shows a heterogeneous spatial distribution in the intermediate host (microtus arvalis). to identify the ecological processes responsible for this heterogeneity, we developed a spatially explicit simulation model. the model combines individual-based (foxes, vulpes vulpes) and grid-based (voles) techniques to simulate the infections in both intermediate and definite host. if host populations are homogeneously mixed, the model reproduces field da ...200414711588
echinococcus multilocularis in belgium: prevalence in red foxes (vulpes vulpes) and in different species of potential intermediate hosts.echinococcus multilocularis causes a rare but potentially lethal zoonotic infection in humans. this tapeworm is known to be endemic in foxes in several countries of western and central europe. in western europe, the common vole (microtus arvalis) and the water vole (arvicola terrestris) are considered to be the most important intermediate host species of this cestode whereas the red fox is by far the most important final host. the purpose of this study was to provide data on the prevalences in w ...200818164551
extraintestinal helminths of the common vole (microtus arvalis) and the water vole (arvicola terrestris) in western austria (vorarlberg).between september and december 2004, a total of 411 voles (318 common voles and 93 water voles) were caught in the austrian province of vorarlberg (lustenau, hohenems, and dornbirn) and were examined by macroscopy, microscopy, and molecular biological analysis to determine the presence and extent of medically important extraintestinal helminths. the following extraintestinal helminth species were detected: taenia taeniaeformis (liver), calodium hepaticum (liver), and echinococcus multilocularis ...201020148339
predator dietary response to prey density variation and consequences for cestode transmission.the functional response of predators to prey density variations has previously been investigated in order to understand predation patterns. however, the consequences of functional response on parasite transmission remain largely unexplored. the rodents microtus arvalis and arvicola terrestris are the main prey of the red fox vulpes vulpes in eastern france. these species are intermediate and definitive hosts of the cestode echinococcus multilocularis. we explored the dietary and contamination re ...201020461413
a real-time multiplex-nested pcr system for coprological diagnosis of echinococcus multilocularis and host species.a hybridization probe-based real-time multiplex-nested pcr system was developed for the simultaneous detection of echinococcus multilocularis and host species directly from faecal samples. species identification was determined by melting curve analysis. specificity was assessed by using dna extracted from various cestodes (e. multilocularis, echinococcus granulosus (g1), echinococcus ortleppi, echinococcus canadensis (g6, g7), taenia crassiceps, taenia hydatigena, taenia mustelae, taenia pisifor ...201121327991
harmonizing methods for wildlife abundance estimation and pathogen detection in europe-a questionnaire survey on three selected host-pathogen combinations.the need for wildlife health surveillance as part of disease control in wildlife, domestic animals and humans on the global level is widely recognized. however, the objectives, methods and intensity of existing wildlife health surveillance programs vary greatly among european countries, resulting in a patchwork of data that are difficult to merge and compare. this survey aimed at evaluating the need and potential for data harmonization in wildlife health in europe. the specific objective was to ...201728202055
establishment and development of echinococcus multilocularis metacestodes in the common vole (microtus arvalis) after oral inoculation with parasite eggs.transmission of the zoonotic tapeworm, echinococcus multilocularis mainly occurs between the red fox (vulpes vulpes) and various species of vole. microtus arvalis is considered one of the key intermediate hosts in europe. we infected 21 m. arvalis aged 35 days (n=2), 56 days (n=6), 84 days (n=4) and 263 days (n=9) with 100 e. multilocularis eggs. four voles aged 263 days were euthanized at 6 weeks post inoculation (wpi) with the remainder euthanized 10 wpi for analysis of metacestode growth and ...201526279253
stability of the southern european border of echinococcus multilocularis in the alps: evidence that microtus arvalis is a limiting factor.summary the known range of the zoonotic fox tapeworm echinococcus multilocularis has expanded since the 1990s, and today this parasite is recorded in higher abundances throughout large parts of europe. this phenomenon is mostly attributed to the increasing european fox populations and their invasion of urban habitats. however, these factors alone are insufficient to explain the heterogeneous distribution of the parasite in europe. here, we analysed the spatial interrelationship of e. multilocula ...201424932666
nutrias and muskrats as bioindicators for the presence of echinococcus multilocularis in new endemic areas.nutrias (myocastor coypus) and muskrats (ondatra zibethicus) are large invasive semi-aquatic or aquatic rodents, naturalized throughout europe. they are regarded as pests, and can be infected with several pathogens and parasites transmissible to wildlife, livestock, pets and humans. as a rule, in europe the life cycle of the cestode echinococcus multilocularis involves red foxes (vulpes vulpes) as main definitive hosts and common voles as intermediate hosts. the suitability of nutrias and muskra ...201323725822
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