Publications

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the migration and development of filaroides hirthi larvae in dogs. 1979542320
fatal filaroides hirthi infection in a dog. 1978659319
filaroides hirthi hyperinfection associated with adrenal cortical carcinoma in a dog.an adrenal cortical carcinoma, verminous pneumonia and hepatic parasitic granulomas were found at necropsy in a 10-year-old castrated male dalmatian. filaroides hirthi hyperinfection due to endogenous cortisol production was diagnosed on the basis of clinical and clinicopathological evidence of hyperadrenocorticism, pathological findings and parasite identification.19873597854
filaroides hirthi infection in a dog.a 5- to 7-month old, female dog developed a cough and labored breathing. filaroides hirthi larvae were recovered from a fecal specimen by use of sodium nitrate flotation and direct saline solution mount. verminous pneumonia caused by f hirthi was diagnosed. the dog appeared to be immunocompetent, and responded to treatment with fenbendazole.19863744982
filaroides hirthi in a british bred beagle dog.filaroides hirthi was identified in large numbers in the lungs of a british bred beagle dog that had received 10 monthly intra-articular injections of a corticosteroid. the dog was terminally hyperpnoeic and eosinophil and reticulocyte counts were raised. at autopsy, the lungs failed to collapse and minute black and red foci were found throughout the lung parenchyma. these foci were identified histologically as parasites and focal haemorrhage. migrating larvae were found in the liver and mesente ...19854024445
filaroides hirthi: hyperinfective lungworm infection in immunosuppressed dogs.filaroides hirthi is a pulmonary parasite found primarily in beagle dogs. the modes of transmission and the life cycle of this parasite have been described recently, and the possibility of an autoinfectious cycle has been suggested. in this paper, we report two cases of experimentally immunosuppressed beagles (4 mg/day of prednisolone for over four months) in which massive disseminated f. hirthi infections developed. large numbers of f. hirthi adults were present in the lungs, and larvae were fo ...19846730225
filaroides hirthi in dogs. 19836838440
verminous pneumonia due to filaroides hirthi in a scottish terrier in spain.a previously healthy scottish terrier developed verminous pneumonia due to filaroides hirthi. the disease was diagnosed on the basis of cytology of a transtracheal wash, which contained 17 per cent eosinophils and a large number of parasite larvae. treatment with 50 mg/kg bodyweight fenbendazole daily for three weeks eliminated the parasites and improved the clinical condition of the dog.200516272546
identification of first-stage larvae of metastrongyles from dogs.by examining larvae from dogs in which the adult stages had been identified, the morphology of angiostrongylus vasorum, filaroides osleri, filaroides hirthi and crenosoma vulpis from samples of faeces or bronchoalveolar lavage was compared. the tail morphology of the four species was distinctive: a vasorum had a typical cuticular indentation and projection on the dorsal surface of the tail (referred to as the dorsal notch and dorsal spine, respectively) and a smaller indentation on the ventral s ...200919717830
filaroides hirthi verminous pneumonia in a west highland white terrier bred in ireland.a two-year-old west highland white terrier, which had failed to thrive from six months of age, presented with acute onset dyspnoea. radiography showed a diffuse pulmonary infiltrate throughout both lungs. haematological abnormalities were an absolute neutrophilia and eosinophilia. postmortem examination revealed uniform consolidation of both lungs which was defined histologically as a verminous granulomatous pneumonia. metastrongyle larvae, isolated from the pulmonary tissue, had the morphologic ...19979179820
lungworm infection in laboratory dogs reared in italy.lungworms, filaroides hirthi, were observed in histological lung sections in 4 out of 96 beagle dogs (4.2%) reared for experimental studies in italy. infected animals were 2 males and 2 females, 8 months old, with no clinical signs, while in another case a granulomatous lesion, possibly transmitted by this lungworm, was found. histopathological changes of lung induced by f. hirthi can mimic some drug-induced and neoplastic lesions, and therefore to cause misunderstanding during interpretation of ...19958532374
lungworm infection in a beagle colony: filaroides hirthi, a common but not well-known companion.116 beagle dogs of both sexes were examined for infection with filaroides hirthi within the framework of several toxicological studies. 98% of the animals demonstrated lung-worm-associated lesions. most of the macroscopic visible lesions can be subdivided into four groups, representing different histopathological pictures ranging from living worms, different types of granulomatous inflammation to tumorlike lesions. especially the latter is liable for several misinterpretations in toxicologic stu ...19948086787
filaroides hirthi in a dog: fatal hyperinfection suggestive of autoinfection.progressive dyspnea in a dog began 1 month after it had been hit by a car. radiographs revealed diffuse interstitial and alveolar pneumonia. large numbers of embryonated eggs were observed in bronchial washings; and many small nematodes, later identified as filaroides hirthi, were found in the fine needle aspirates of pulmonary tissue. numerous nematode larvae were demonstrated on fecal flotation. the severe hyperinfection strongly suggested autoinfection, probably associated with depressed immu ...19807358551
filaroides hirthi infection in two related dogs.filaroides hirthi infection was diagnosed in 2 related yorkshire terriers. dog 1 had a chronic nonproductive cough, but results of fecal flotation examination were negative. dog 2 was a 1-year-old female progeny of dog 1. both dogs came from the same kennel and were raised together for 8 weeks. dog 2 had generalized demodicosis accompanied by secondary bacterial infection and had been treated with corticosteroids. dog 2 also was given 68 micrograms of ivermectin, po, and then 50 mg of fenbendazo ...19883204055
filaroides hirthi: experimental transmission among beagle dogs through ingestion of first-stage larvae.four beagle dogs were found to be infected with sexually mature filaroides hirthi lungworms from 1 to 3 months after they ingested material containing first-stage larvae opens the theoretical possibility of autoinfection of which few nematode parasites are capable.1976982040
patency and transmission of filaroides hirthi infection.filaroides hirthi lungworm infection was diagnosed by the recovery of 1st-stage larvae from the faeces of dogs with heavy, artificially induced infections using zinc sulphate flotation. diagnosis of low-grade natural infections was infrequently achieved. zinc sulphate flotation was demonstrated to be about 100 times as efficient as the baermann technique in concentrating f. hirthi larvae from dog faeces. larvae recovered from faeces proved to be infective when fed to a pup and it was concluded t ...1977927891
anthelmintic activity of albendazole against filaroides hirthi lungworms in dogs.albendazole given at a dosage rate of 25 to 50 mg/kg twice daily for 5 days killed all but a small proportion and sterilized the few surviving filaroides hirthi worms in artificially infected beagle pups. extensive tissue reaction around the dead worms persisted for an undetermined length of time. however, albendazole treatment of mature stock should prove useful in preventing transmission of f hirthi infection to their offspring and thus provide an efficient means of control.1978727579
transmission and control of filaroides hirthi lungworm infection in dogs.transmission of filaroides hirthi among cagemate pups was demonstrated to occur through the ingestion of first-stage larvae in recently passed feces. it was suggested that coprophagia is the principal mechanism of transmission of f hirthi and that transmission from brood bitches to their litters occurs by this mechanism during and after the fourth or fifth week of the nursing period. medication of 15 infected brood bitches with two courses of albendazole at a dosage rate of 50 mg/kg of body weig ...1979475134
prevalence of angiostrongylus vasorum and crenosomo vulpis in dogs in bavaria.worldwide there is increasing awareness of canine lung worm infection in many geographic areas. especially the metastrongyloid nematode angiostrongylus (a.) vasorum is associated with a high morbidity and mortality rate in infected dogs. other pulmonary parasites in dogs include the common fox parasite crenosoma (c.) vulpis, and the pulmonary parasites filaroides (oslerus) osleri, filaroides hirthi, and the capillarid lungworms eucoleus aerophilus (capillaria aerophila) and eucoleus boehmi. aim ...201323367670
what is your diagnosis? filaroides hirthi infection. 200010759376
massive filaroides hirthi infestation associated with canine distemper in a puppy. 19979023910
control of filaroides hirthi infections in beagle dogs by ivermectin.the efficacy of ivermectin against filaroides hirthi was evaluated in a series of three trials using beagle dogs of a breeding colony known to be endemically infected with this lungworm. ivermectin was subcutaneously given at a dosage of 1 mg kg-1 bodyweight once to 40 (group a) or, at a one week interval, twice to 32 dogs (group b) 14-15 weeks prior to necropsy; another 40 dogs (group c) remained untreated. all animals were necropsied and lungs were digested using the pepsin-hydrochloride metho ...19968983152
control of filaroides hirthi in commercially reared beagle dogs.two commercial research beagle breeding colonies began a control program for filaroides hirthi. all stud dogs and all nonpregnant, nonlactating brood bitches were given two courses, 2-4 weeks apart, of 25 mg/kg body weight albendazole per os twice daily for 5 days. puppies of treated dams were isolated from puppies of nontreated dams. the proportions of infected puppies of puppies killed in 1979 were 45% and 78% from the two colonies. after 1979, the proportions were 0.2% and 24%. one colony may ...19827144116
filaroides hirthi sp. n. (nematoda: metastrongyloidea) from the lung of the dog.filaroides hirthi sp. n. is smaller than previously described species of the genus filaroides v. beneden, 1858, and differs from f. milksi whitlock, 1956, with which it is most likely to be confused, in having shorter, slightly stouter spicules with a broader proximal knob for attachment of the retractor muscles.19751127563
preliminary investigation of the life history of filaroides hirthi georgi and anderson, 1975.filaroides hirthi lungworm infection increased as a function of age among 47, 9 to 32 week old beagle pups at a commercial breeding establishment. probit analysis of these data yielded an estimate of 50% infection was by age 17.4 +/- 3.7 weeks. this parasite and/or its associated lesions remained in at least 40% of infected beagles at least 10 months after exposure to infection had ceased. reinfection rendered improbable by the nature of the new environment, a laboratory animal colony. repeated ...1976954439
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